Search Results - "Ragot, Thierry"

Aluminum particles generated during millisecond electric pulse application enhance adenovirus-mediated gene transfer in L929 cells by Tesse, Angela, André, Franck M., Ragot, Thierry

“…Gene electrotransfer is an attractive method of non-viral gene delivery. However, the mechanism of DNA penetration across the plasma membrane is widely…”
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Detrimental arterial inflammatory effect of microparticles circulating in preeclamptic women: ex vivo evaluation in human arteries by Boisramé-Helms, Julie, Meziani, Ferhat, Sananès, Nicolas, Boisramé, Thomas, Langer, Bruno, Schneider, Francis, Ragot, Thierry, Andriantsitohaina, Ramaroson, Tesse, Angela

“…Elevated plasmatic levels of lympho‐monocyte and platelet microparticles (MPs) have been reported in preeclampsia. Previous studies suggest that MPs could…”
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PPARδ Activity in Cardiovascular Diseases: A Potential Pharmacological Target by Tesse, Angela, Andriantsitohaina, Ramaroson, Ragot, Thierry

“…Activation of peroxisome proliferator-activated receptors (PPARs), and particularly of PPARα and PPARγ, using selective agonists, is currently used in the…”
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Efficient adenovirus-mediated transfer of a human minidystrophin gene to skeletal muscle of mdx mice by Ragot, Thierry, Vincent, Nathalie, Chafey, Philippe, Vigne, Emmanuelle, Gilgenkrantz, Hélène, Coutont, Dominque, Cartaud, Jean, Briand, Pascale, Kaplant, Jean-Claude, Perricaude, Michel, Kahn, Axel

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361. Metallic Particles Generated During Electric Pulses Enhance Adenovirus-Mediated Gene Transfer by Ragot, Thierry, Azan, Antoine, Mir, Lluis M.

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Abstract 2656: Muscle wasting in head and neck carcinomas: Investigations on the underlying transcriptional reprogrammation by Hachicha, Héla, Pirozhkova, Iryna, Gelin, Aurore, Bidault, François, Rouffiac, Valérie, Dayris, Thibault, Ragot, Thierry, Breuskin, Ingrid, Even, Caroline, Gorphe, Philippe, Busson, Pierre

“…Abstract Introduction: Cancer cachexia is a multifactorial syndrome associated with a skeletal muscle atrophy that affects at least 55% of patients bearing…”
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Apoptosis induction by combination of drugs or a conjugated molecule associating non-steroidal anti-inflammatory and nitric oxide donor effects in medullary thyroid cancer models: implication of the tumor suppressor p73 by Ragot, Thierry, Provost, Claire, Prignon, Aurélie, Cohen, Régis, Lepoivre, Michel, Lausson, Sylvie

“…Medullary thyroid cancer (MTC) is a C-cell neoplasm. Surgery remains its main treatment. Promising therapies based on tyrosine kinase inhibitors demand careful…”
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Cyclooxygenase-2-Derived Prostacyclin Protective Role on Endotoxin-Induced Mouse Cardiomyocyte Mortality by Panaro, Maria Antonietta, Pricci, Maria, Meziani, Ferhat, Ragot, Thierry, Andriantsitohaina, Ramaroson, Mitolo, Vincenzo, Tesse, Angela

“…Cardiovascular dysfunction characterizes septic shock, inducing multiple organ failure and a high mortality rate. In the heart, it has been shown an…”
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PPAR[delta] Activity in Cardiovascular Diseases: A Potential Pharmacological Target by Tesse, Angela, Ramaroson Andriantsitohaina, Ragot, Thierry

“…Activation of peroxisome proliferator-activated receptors (PPARs), and particularly of PPARα and PPARγ , using selective agonists, is currently used in the…”
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PPARγ activity in cardiovascular diseases: a potential pharmacological target by Tesse, Angela, Andriantsitohaina, Ramaroson, Ragot, Thierry

“…Activation of peroxisome proliferator-activated receptors (PPARs), and particularly of PPARα and PPARγ, using selective agonists, is currently used in the…”
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Efficient adenovirus-mediated transfer of a human minidystrophin gene to skeletal muscle of mdx mice by Ragot, T, Vincent, N, Chafey, P, Vigne, E, Gilgenkrantz, H, Couton, D, Cartaud, J, Briand, P, Kaplan, J C, Perricaudet, M

“…Duchenne progressive muscular dystrophy is a lethal and common X-linked genetic disease caused by the absence of dystrophin, a 427K protein encoded by a 14…”
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Medullary thyroid carcinoma arises in the absence of prolactin signaling by KEDZIA, Cécile, LACROIX, Ludovic, AMEUR, Nabahet, RAGOT, Thierry, KELLY, Paul A, CAILLOU, Bernard, BINART, Nadine

“…Prolactin, a pituitary hormone, exerts pleiotropic effects in various cells. These effects are mediated by a membrane receptor highly expressed in many…”
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Percutaneous intracoronary delivery of SERCA gene increases myocardial function: a tissue Doppler imaging echocardiographic study by Logeart, Damien, Vinet, Laurent, Ragot, Thierry, Heimburger, Michèle, Louedec, Liliane, Michel, Jean-Baptiste, Escoubet, Brigitte, Mercadier, Jean-Jacques

“…The aim of this study was to examine the efficiency of adenovirus-mediated overexpression of sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA1a) gene in a…”
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Long-term correction of mouse dystrophic degeneration by adenovirus-mediated transfer of a minidystrophin gene by Grégoire, Anne, Couton, Dominique, Chafey, Philippe, Briand, Pascale, Vincent, Nathalie, Ragot, Thierry, Kaplan, Jean-Claude, Perricaudet, Michel, Kahn, Axel, Gilgenkrantz, Hélè

“…Duchene muscular dystrophy (DMD) is a fatal progressive X-linked muscle disorder, caused by mutations in the dystrophin gene. We have investigated…”
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Phase I Study of a Recombinant Adenovirus-Mediated Gene Transfer in Lung Cancer Patients by Tursz, Thomas, Le Cesne, Axel, Baldeyrou, Pierre, Gautier, Eric, Opolon, Paule, Schatz, Christian, Pavirani, Andrea, Courtney, Michael, Lamy, Didier, Ragot, Thierry, Saulnier, Patrick, Andremont, Antoine, Monier, Roger, Perricaudet, Michel, Le Chevalier, Thierry

“…Background Despite vigorous efforts at curbing tobacco consumption and aggressive combined-modality treatment programs, both the incidence of and the mortality…”
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Arterial gene transfer to rabbit endothelial and smooth muscle cells using percutaneous delivery of an adenoviral vector by Steg, P G, Feldman, L J, Scoazec, J Y, Tahlil, O, Barry, J J, Boulechfar, S, Ragot, T, Isner, J M, Perricaudet, M

“…Previous investigations in live animals convincingly established that arterial gene transfer, while feasible, was compromised by a low transfection efficiency…”
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Adenoviral SERCA1a gene transfer to adult rat ventricular myocytes induces physiological changes in calcium handling by CHOSSAT, Nathalie, GRISCELLI, Frank, JOURDON, Philippe, LOGEART, Damien, RAGOT, Thierry, HEIMBURGER, Michèle, PERRICAUDET, Michel, LOMPRE, Anne-Marie, HATEM, Stéphane, MERCADIER, Jean-Jacques

“…We examined the functional consequences of expressing adult rabbit fast skeletal sarcoplasmic reticulum (SR) Ca(2+)-ATPase (SERCA1a) in isolated adult rat…”
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Complete recovery of mice from a pre-established tumor by direct intratumoral delivery of an adenovirus vector harboring the murine IL-2 gene by Cordier, L, Duffour, M T, Sabourin, J C, Lee, M G, Cabannes, J, Ragot, T, Perricaudet, M, Haddada, H

“…Direct introduction of exogenous genes into pre-existent tumors could provide an effective therapeutic approach for treatment of localized tumors. In this…”
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Adenoviral interleukin-2 gene transfer into P815 tumor cells abrogates tumorigenicity and induces antitumoral immunity in mice by Haddada, H, Ragot, T, Cordier, L, Duffour, M T, Perricaudet, M

“…The murine mastocytoma cell line P815 was used as a model to evaluate the effect on its tumorigenic capacity following interleukin-2 (IL-2) gene transfer into…”
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Heart-specific targeting of beta-galactosidase by the ventricle-specific cardiac myosin light chain 2 promoter using adenovirus vectors by Griscelli, F, Gilardi-Hebenstreit, P, Hanania, N, Franz, W M, Opolon, P, Perricaudet, M, Ragot, T

“…Adenoviruses are attractive vectors for gene transfer into cardiac muscle. However, their promiscuous tissue tropism, which leads to an ectopic expression of…”
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