Search Results - "Ragot, Kevin"

7-Ketocholesterol is increased in the plasma of X-ALD patients and induces peroxisomal modifications in microglial cells: Potential roles of 7-ketocholesterol in the pathophysiology of X-ALD by Nury, Thomas, Zarrouk, Amira, Ragot, Kévin, Debbabi, Meryam, Riedinger, Jean-Marc, Vejux, Anne, Aubourg, Patrick, Lizard, Gérard

“…[Display omitted] •Plasma levels of GSH, α-tocopherol, and docosahexaenoic acid are decreased in X-ALD.•7-Ketocholesterol, 7β- and 7α-hydroxycholesrol, and…”
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Absence of correlation between oxysterol accumulation in lipid raft microdomains, calcium increase, and apoptosis induction on 158N murine oligodendrocytes by Ragot, Kévin, Mackrill, John J., Zarrouk, Amira, Nury, Thomas, Aires, Virginie, Jacquin, Agnès, Athias, Anne, Barros, Jean-Paul Pais de, Véjux, Anne, Riedinger, Jean-Marc, Delmas, Dominique, Lizard, Gérard

“…The ability of oxysterols (7-ketocholesterol, 7β-hydroxycholesterol) to trigger a mode of cell death by apoptosis involving GSK-3 and caspase-3 activation is…”
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α-Tocopherol impairs 7-ketocholesterol-induced caspase-3-dependent apoptosis involving GSK-3 activation and Mcl-1 degradation on 158N murine oligodendrocytes by Ragot, Kévin, Delmas, Dominique, Athias, Anne, Nury, Thomas, Baarine, Mauhamad, Lizard, Gérard

“…► This manuscript described new data on the mechanism of action associated with 7-ketocholesterol-induced cell death by apoptosis on oligodendrocytes. ► It…”
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A moderate red wine intake improves blood lipid parameters and erythrocytes membrane fluidity in post myocardial infarct patients by Rifler, Jean-Pierre, Lorcerie, Fanny, Durand, Philippe, Delmas, Dominique, Ragot, Kévin, Limagne, Emeric, Mazué, Frédéric, Riedinger, Jean-Marc, d'Athis, Philippe, Hudelot, Bernard, Prost, Michel, Lizard, Gérard, Latruffe, Norbert

“…While the cardioprotective effect of moderate and regular wine consumption in primary prevention has been well documented, the goal of the present…”
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Glycogen synthase kinase 3 involvement in the excessive proinflammatory response to LPS in patients with decompensated cirrhosis by Coant, Nicolas, Simon-Rudler, Marika, Gustot, Thierry, Fasseu, Magali, Gandoura, Sonia, Ragot, Kévin, Abdel-Razek, Waël, Thabut, Dominique, Lettéron, Philippe, Ogier-Denis, Eric, Ouziel, Romy, Devière, Jacques, Lizard, Gérard, Tellier, Zéra, Lebrec, Didier, Moreau, Richard

“…Background & Aims In decompensated cirrhosis, the early innate immune response to the Toll-like receptor 4 (TLR4) agonist, lipopolysaccharides (LPS), is…”
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Performance evaluation of human cytokines profiles obtained by various multiplexed-based technologies underlines a need for standardization by Dupuy, Anne Marie, Kuster, Nils, Lizard, Gérard, Ragot, Kévin, Lehmann, Sylvain, Gallix, Benoît, Cristol, Jean Paul

“…Multiplexed methods permit simultaneous quantification of multiple cytokines. As several manufacturers offer reagents to quantify the same cytokines on a…”
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Incidence of Abcd1 level on the induction of cell death and organelle dysfunctions triggered by very long chain fatty acids and TNF-α on oligodendrocytes and astrocytes by Baarine, Mauhamad, Ragot, Kévin, Athias, Anne, Nury, Thomas, Kattan, Zilal, Genin, Emmanuelle C., Andreoletti, Pierre, Ménétrier, Franck, Riedinger, Jean-Marc, Bardou, Marc, Lizard, Gérard

“…► Effects of C24:0 and C26:0 on various types of oligodendrocytes and astrocytes: cell lines (158N murine oligodendrocytes, rat C6 glioma cells), rat primary…”
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CORRELATIONAL SELECTION ON PRO- AND ANTI-INFLAMMATORY EFFECTORS by Guerreiro, Romain, Besson, Anne A., Bellenger, Jérôme, Ragot, Kévin, Lizard, Gérard, Faivre, Bruno, Sorci, Gabriele

“…Parasites impose a permanent threat for hosts. As a consequence, immune defenses are important for host fitness. However, the immune response can also produce…”
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Impact of 7‐ketocholesterol and very long chain fatty acids on oligodendrocyte lipid membrane organization: Evaluation via LAURDAN and FAMIS spectral image analysis by Kahn, Edmond, Baarine, Mauhamad, Dauphin, Aurélien, Ragot, Kévin, Tissot, Nicolas, Seguin, Alix, Ménétrier, Franck, Kattan, Zilal, Bachelet, Claude‐Marie, Frouin, Frédérique, Lizard, Gérard

“…In the context of multiple sclerosis and X‐linked adrenoleukodystrophy, 7‐ketocholesterol (7KC) and very long chain fatty acids (C24:0, C26:0) are supposed to…”
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Phase I study of OM-174, a lipid A analogue, with assessment of immunological response, in patients with refractory solid tumors by Isambert, Nicolas, Fumoleau, Pierre, Paul, Catherine, Ferrand, Christophe, Zanetta, Sylvie, Bauer, Jacques, Ragot, Kevin, Lizard, Gérard, Jeannin, Jean-François, Bardou, Marc

“…Lipids A, the lipophilic partial structure of lipopolysaccharides, induce regression of several tumor types in animal models. Rather than exerting direct…”
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Parental experience of a risky environment leads to improved offspring growth rate by Besson, Anne A, Guerreiro, Romain, Bellenger, Jérôme, Ragot, Kevin, Faivre, Bruno, Sorci, Gabriele

“…Parasites (or diseases) are a major selective force for the evolution of life history traits and parasite-host evolution. Mothers can show a variety of…”
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Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: cytoprotective effects and prevention of VEGF secretion by resveratrol by Dugas, B., Charbonnier, S., Baarine, M., Ragot, K., Delmas, D., Ménétrier, F., Lherminier, J., Malvitte, L., Khalfaoui, T., Bron, A., Creuzot-Garcher, C., Latruffe, N., Lizard, Gérard

“…Background and aims Oxysterols are assumed to play important roles in age-related macular degeneration, a major cause of blindness. So we characterized the…”
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The Inflammatory Response in Acyl-CoA Oxidase 1 Deficiency (Pseudoneonatal Adrenoleukodystrophy) by El Hajj, H. I, Vluggens, A, Andreoletti, P, Ragot, K, Mandard, S, Kersten, S, Waterham, H. R, Lizard, G, Wanders, R. J. A, Reddy, J. K, Cherkaoui-Malki, Mustapha

“…Among several peroxisomal neurodegenerative disorders, the pseudoneonatal adrenoleukodystrophy (P-NALD) is characterized by the acyl-coenzyme A oxidase 1…”
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Peroxisomal and mitochondrial status of two murine oligodendrocytic cell lines (158N, 158JP): potential models for the study of peroxisomal disorders associated with dysmyelination processes by Baarine, Mauhamad, Ragot, Kevin, Genin, Emmanuelle C., El Hajj, Hammam, Trompier, Doriane, Andreoletti, Pierre, Ghandour, M. Said, Menetrier, Franck, Cherkaoui‐Malki, Mustapha, Savary, Stephane, Lizard, Gerard

“…In some neurodegenerative disorders (leukodystrophies) characterized by myelin alterations, the defect of peroxisomal functions on myelin‐producing cells…”
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Analysis of the capture and influence of nanoparticles on the cytotoxic effects of 7-ketocholesterol on cardiac cells: investigation by flow cytometry and by dynamic and spectral imaging microscopy associated with factor analysis of medical image sequences by Kahn, Edmond, Pelloux, Sophie, Baarine, Mauhamad, Khalfaoui, Taoufik, Ragot, Kévin, Frouin, Frédérique, Riedinger, Jean-Marc, Tourneur, Yves, Lizard, Gérard

“…To evaluate the capture of nanoparticles (quantum dots [QDs], fluorospheres) by nonbeating mouse cardiac cells (HL1-NB) cultured without or with…”
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Peroxisomal and mitochondrial status of two murine oligodendrocytic cell lines (158N, 158JP): potential models for the study of peroxisomal disorders associated with dysmyelination processes: Peroxisomal and Mitochondrial Status of Two Differentiated Murine Oligodendrocytic Cell Lines (158N, 158JP) by Baarine, Mauhamad, Ragot, Kevin, Genin, Emmanuelle C., El Hajj, Hammam, Trompier, Doriane, Andreoletti, Pierre, Ghandour, M Said, Ménétrier, Franck, Cherkaoui-Malki, Mustapha, Savary, Stéphane, Lizard, Gérard

“…In some neurodegenerative disorders (leukodystrophies) characterized by myelin alterations, the defect of peroxisomal functions on myelin-producing cells…”
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A moderate red wine intake improves blood lipid parameters and erythrocytes membrane fluidity in post myocardial infarct patients by Rifler, Jean-Pierre, Lorcerie, Fanny, Durand, Philippe, Delmas, Dominique, Ragot, Kévin, Limagne, Emeric, Mazué, Frédéric, Riedinger, Jean-Marc, d'Athis, Philippe, Hudelot, Bernard, Prost, Michel, Lizard, Gérard, Latruffe, Norbert

“…While the cardioprotective effect of moderate and regular wine consumption in primary prevention has been well documented, the goal of the present…”
Get full text