Search Results - "Raghu, Kozhiparambil Gopalan"

Recent advances on nanoparticle-based therapies for cardiovascular diseases by Soumya, Rema Sreenivasan, Raghu, Kozhiparambil Gopalan

“…•Nanoparticles based therapeutics for cardiovascular disease.•Application of nanoparticles in biomedical imaging for cardiovascular disease…”
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An Overview on Arsenic Trioxide-Induced Cardiotoxicity by Vineetha, Vadavanath Prabhakaran, Raghu, Kozhiparambil Gopalan

“…Arsenic trioxide (ATO) is among the first-line chemotherapeutic drugs used in oncological practice. It has shown substantial efficacy in treating patients with…”
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Protective effect of Boerhaavia diffusa L. against mitochondrial dysfunction in angiotensin II induced hypertrophy in H9c2 cardiomyoblast cells by Prathapan, Ayyappan, Vineetha, Vadavanath Prabhakaran, Raghu, Kozhiparambil Gopalan

“…Mitochondrial dysfunction plays a critical role in the development of cardiac hypertrophy and heart failure. So mitochondria are emerging as one of the…”
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Vanillic acid mitigates the impairments in glucose metabolism in HepG2 cells through BAD–GK interaction during hyperinsulinemia by Sreelekshmi, Mohan, Raghu, Kozhiparambil Gopalan

“…Glucokinase (GK), a key regulator of hepatic glucose metabolism in the liver and glucose sensor and mediator in the secretion of insulin in the pancreas, is…”
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Phloretin Alleviates Arsenic Trioxide-Induced Apoptosis of H9c2 Cardiomyoblasts via Downregulation in Ca2+/Calcineurin/NFATc Pathway and Inflammatory Cytokine Release by Vadavanath Prabhakaran, Vineetha, Kozhiparambil Gopalan, Raghu

“…Arsenic trioxide (ATO) is among the first-line chemotherapeutic drugs for treating acute promyelocytic leukemia patients, but its clinical use is hampered due…”
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Significance of mitochondria on cardiometabolic syndromes by Anupama, Nair, Sindhu, Ganapathy, Raghu, Kozhiparambil Gopalan

“…Metabolic syndromes (MS) are a cluster of disorders such as obesity, hypertension, dyslipidemia, and diabetes. Cardiometabolic syndrome (CMS), a branch of MS,…”
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Preparation and characterization of selenium incorporated guar gum nanoparticle and its interaction with H9c2 cells by Soumya, Rema Sreenivasan, Vineetha, Vadavanath Prabhakaran, Reshma, Premachandran Latha, Raghu, Kozhiparambil Gopalan

“…This study deals with the preparation and characterization of selenium incorporated guar gum nanoparticle (SGG), and its effect on H9c2 cardiomyoblast. Herein,…”
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In vitro antibacterial effects of combination of ciprofloxacin with compounds isolated from Streptomyces luteireticuli NIIST-D75 by Jesmina, Abdul Rasheed Safiya, Induja, D. K., Drissya, Thankappan, Sruthi, Chakiniplackal Rajan, Raghu, Kozhiparambil Gopalan, Nelson-Sathi, Shijulal, Kumar, Bhaskaran Nair Saraswathy Amma Dileep, Lankalapalli, Ravi S.

“…Three phenazines, 1-methoxyphenazine ( 1 ), methyl-6-methoxyphenazine-1-carboxylate ( 2 ), 1,6-dimethoxyphenazine ( 4 ), and a 2,3-dimethoxy benzamide ( 3 )…”
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Desmodium gangeticum (Linn.) DC. Exhibits Antihypertrophic Effect in Isoproterenol-Induced Cardiomyoblasts via Amelioration of Oxidative Stress and Mitochondrial Alterations by Sankar, Vandana, Pangayarselvi, Balasubramaniam, Prathapan, Ayyappan, Raghu, Kozhiparambil Gopalan

“…Cardiac hypertrophy occurs in response to increased workload, such as hypertension or valvular heart disease. Oxidative stress has been implicated in cardiac…”
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Attenuation of Oxidative Damage by Boerhaavia diffusa L. Against Different Neurotoxic Agents in Rat Brain Homogenate by Ayyappan, Prathapan, Palayyan, Salin Raj, Kozhiparambil Gopalan, Raghu

“…Due to a high rate of oxidative metabolic activity in the brain, intense production of reactive oxygen metabolite occurs, and the subsequent generation of free…”
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Joubert syndrome causing mutation in C2 domain of CC2D2A affects structural integrity of cilia and cellular signaling molecules by Jayarajan, Roopasree O., Chakraborty, Soura, Raghu, Kozhiparambil Gopalan, Purushothaman, Jayamurthy, Veleri, Shobi

“…Cilia are organelles extend from cells to sense external signals for tuning intracellular signaling for optimal cellular functioning. They have evolved sensory…”
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Phloretin Alleviates Arsenic Trioxide-Induced Apoptosis of H9c2 Cardiomyoblasts via Downregulation in Ca.sup.2+/Calcineurin/NFATc Pathway and Inflammatory Cytokine Release by Vadavanath Prabhakaran, Vineetha, Kozhiparambil Gopalan, Raghu

“…Arsenic trioxide (ATO) is among the first-line chemotherapeutic drugs for treating acute promyelocytic leukemia patients, but its clinical use is hampered due…”
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Phloretin ameliorates arsenic trioxide induced mitochondrial dysfunction in H9c2 cardiomyoblasts mediated via alterations in membrane permeability and ETC complexes by Vineetha, Vadavanath Prabhakaran, Soumya, Rema Sreenivasan, Raghu, Kozhiparambil Gopalan

“…Arsenic trioxide (ATO), though a very effective drug for the treatment of acute promyelocytic leukemia, leads to cardiotoxicity. As mitochondria are the center…”
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An in vitro study reveals the anti-obesity effects of 7- methoxy-3-methyl-5-((E)-prop-1-enyl)-2-(3,4,5-trimethoxyphenyl)-2,3-dihydrobenzofuran from Myristica fragrans by Shyni, Gangadharan Leela, Sajin, Kaithathara Francis, Mangalam, Sivasankaran Nair, Raghu, Kozhiparambil Gopalan

“…Adipogenesis, the maturation process of preadipocytes, is closely associated with the development of obesity and other complex metabolic syndromes. Herein, we…”
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Phloretin Alleviates Arsenic Trioxide-Induced Apoptosis of H9c2 Cardiomyoblasts via Downregulation in Ca 2+ /Calcineurin/NFATc Pathway and Inflammatory Cytokine Release by Vadavanath Prabhakaran, Vineetha, Kozhiparambil Gopalan, Raghu

“…Arsenic trioxide (ATO) is among the first-line chemotherapeutic drugs for treating acute promyelocytic leukemia patients, but its clinical use is hampered due…”
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Symplocos cochinchinensis enhances insulin sensitivity via the down regulation of lipogenesis and insulin resistance in high energy diet rat model by Antu, Kalathookunnel Antony, Riya, Mariam Philip, Nair, Anupama, Mishra, Arvind, Srivastava, Arvind K., Raghu, Kozhiparambil Gopalan

“…This plant has been utilized in Indian system of medicine for treatment of diabetes. This is clearly evident from the composition of Ayurvedic preparation for…”
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Production and characterization of PHB from a novel isolate Comamonas sp. from a dairy effluent sample and its application in cell culture by Prabisha, Thunoli Payyanvalappil, Sindhu, Raveendran, Binod, Parameswaran, Sankar, Vandana, Raghu, Kozhiparambil Gopalan, Pandey, Ashok

“…•First report on PHB nanomatrices and solid walled matrices from Comamonas sp.•Both matrices showed almost 100% survival of H9c2 cells.•Under optimized…”
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Curcumin improves hypoxia induced dysfunctions in 3T3-L1 adipocytes by protecting mitochondria and down regulating inflammation by Priyanka, Ariyapalli, Anusree, Sasidharan Suseela, Nisha, Vijayakumar Marykutty, Raghu, Kozhiparambil Gopalan

“…Obesity induced metabolic syndrome is increasing worldwide at an alarming rate. It is characterized by excessive expansion of white adipose tissue which leads…”
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in vitro study reveals nutraceutical properties of Ananas comosus (L.) Merr. var. Mauritius fruit residue beneficial to diabetes by Riya, Mariam Philip, Antu, Kalathookunnel Antony, Vinu, Thankamony, Chandrakanth, Karuvakandy Chandrasekharan, Anilkumar, Karunakaran Sasikala, Raghu, Kozhiparambil Gopalan

“…BACKGROUND: Rapid urbanisation and nutritional transition is fuelling the increased global incidence of type 2 diabetes. Pineapple fruit residue was explored…”
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Polyphenol-rich apple (Malus domestica L.) peel extract attenuates arsenic trioxide induced cardiotoxicity in H9c2 cells via its antioxidant activity by Vineetha, Vadavanath Prabhakaran, Girija, Seetharaman, Soumya, Rema Sreenivasan, Raghu, Kozhiparambil Gopalan

“…Evidences suggest that apple peel has a wide range of polyphenols having antioxidant activity and its consumption has been linked with improved health…”
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