Search Results - "Raghavan, Sriram"

ResiDEM: Analytical Tool for Isomorphous Difference Electron Density Maps Utilizing Dynamic Residue Identification via Density Clustering by Srinivasa Raghavan, Sriram, Miyashita, Osamu

“…Time-resolved serial femtosecond crystallography (TR-SFX) of biological molecules captures the time-evolved dynamics of the residual motions across crystal…”
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Sanggenol B, a plant bioactive, as a safer alternative to tackle cancer by antagonising human FGFR by Nagaraj, Achyuta, Srinivasa Raghavan, Sriram, Niraikulam, Ayyadurai, Gautham, Namasivayam, Gunasekaran, Krishnasamy

“…Fibroblast Growth Receptor Factor (FGFR) are a family of proteins which are, in addition to their biological role, are involved in various pathological…”
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Biomimetic strategies to design metallic proteins for detoxification of hazardous heavy metal by J, Asuma Janeena, M, Ilamaran, A, George, S A, George, S, Sriram Raghavan, P, Surya Lakshmi, M, Aarthy, N R, Kamini, K, Gunasekaran, N, Ayyadurai

“…•Synthesis of copper binding proteins for treatment of copper containing wastewater.•Various congener metal binding proteins were designed and screened for…”
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Indexing and matching trajectories under inconsistent sampling rates by Ranu, Sayan, Deepak, P., Telang, Aditya D., Deshpande, Prasad, Raghavan, Sriram

“…Quantifying the similarity between two trajectories is a fundamental operation in analysis of spatio-temporal databases. While a number of distance functions…”
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SDN Security: Developing an organic escalation framework for operational automation on security incidents by Raghavan, Sriram, Raghavan, S. V.

“…The number of actions at a user’s disposal in the digital arena is on the rise; the number of technologies available to track users’ activities in an…”
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A facile method for high level dual expression of recombinant and congener protein in a single expression system by Ilamaran, M., Sriram Raghavan, S., Karthik, S., Sanjay Nalawade, Ketaki, Samvedna, S., Routray, W., Kamini, N.R., Saravanan, P., Ayyadurai, N.

“…Protein engineering is an emerging field for developing novel therapeutic proteins and commercial enzymes, along with a major impact on the global market. In…”
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Design and synthesis of novel tetrahydrofuran cyclic urea derivatives as androgen receptor antagonists by YARAGANI, MURALIKRISHNA, YADLAPALLI, PRASAD, RAGHAVAN, SRIRAM, AYYADURAI, NIRAIKULAM, CHINNUSAMY, SARAVANAN, MANDAVA, VENKATA BASAVESWARA RAO, KOTTAPALLI, RAJASEKHARA PRASAD

“…In order to improve the antiproliferative activity of androgen receptor (AR) antagonists, which used clinically for the treatment of prostate cancer that is a…”
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Epigallocatechin Gallate with Potent Anti-Helicobacter pylori Activity Binds Efficiently to Its Histone-like DNA Binding Protein by Raj, Ritu, Agarwal, Nipanshu, Raghavan, Sriram, Chakraborti, Tapati, Poluri, Krishna Mohan, Pande, Gaurav, Kumar, Dinesh

“…Helicobacter pylori (H. pylori)a human gastric pathogenforms a major risk factor for the development of various gastric pathologies such as chronic…”
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Side chain torsion dictates planarity and ionizability of green fluorescent protein's chromophore leading to spectral perturbations by Raghavan, S. Sriram, Niraikulam, Ayyadurai, Gunasekaran, Krishnasamy

“…Spectral characteristics of fluorescent proteins (FPs) are well studied, and through protein engineering, several FP variants constituting entire visible…”
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Exquisite binding interaction of 18β-Glycyrrhetinic acid with histone like DNA binding protein of Helicobacter pylori: A computational and experimental study by Raj, Ritu, Agarwal, Nipanshu, Raghavan, Sriram, Chakraborti, Tapati, Poluri, Krishna Mohan, Kumar, Dinesh

“…The Histone-like DNA binding protein is one of the most abundant nucleoid associated protein expressed by human gastric-pathogen, Helicobacter pylori (H…”
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Insights in the structural understanding of amyloidogenicity and mutation-led conformational dynamics of amyloid beta (Aβ) through molecular dynamics simulations and principal component analysis by Raghavan, Sriram Srinivasa, Iqbal, Saleem, Ayyadurai, Niraikulam, Gunasekaran, Krishnasamy

“…Abnormal protein aggregation in the nervous tissue leads to several neurodegenerative disorders like Alzheimer's disease (AD). In AD, accumulation of the…”
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Evaluation of action of steroid molecules on SARS-CoV-2 by inhibiting NSP-15, an endoribonuclease by Dhanabalan, Anantha Krishnan, Raghavan, Sriram Srinivasa, Rajendran, Selvakumar, Ramasamy, Velavan, Abdul, Shaik Abdul Azeez, Narayanasamy, Nandhagopal, Krishnasamy, Gunasekaran

“…Many countries in the world have recently experienced an outbreak of COVID-19, turned out to be a pandemic which significantly affected the world economy…”
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Electronic effect‐dependent intramolecular non‐covalent interactions on the activity of 4,4‐dimethylimidazolidin‐2‐one pharmacophore‐based androgen receptor antagonists by Yaragani, Muralikrishna, Yadlapalli, Prasad, Raghavan, Sriram, Giridhar, Thota, Mandava, Venkata Basaveswara Rao, Singh, Ravindra Vikram, Kottapalli, Rajasekhara Prasad, Chinnusamy, Saravanan

“…Because androgen receptor (AR) signalling is important for the development and progression of prostate cancer (PC), AR antagonists are utilized in clinical…”
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Excited State Electronic Interconversion and Structural Transformation of Engineered Red-Emitting Green Fluorescent Protein Mutant by Augustine, George, Raghavan, Sriram, NumbiRamudu, Kamini, Easwaramoorthi, Shanmugam, Shanmugam, Ganesh, Seetharani Murugaiyan, Jaimohan, Gunasekaran, Krishnasamy, Govind, Chinju, Karunakaran, Venugopal, Ayyadurai, Niraikulam

“…Red fluorescent proteins with a large Stokes shift offer a limited autofluorescence background and are used in deep tissue imaging. Here, by introducing the…”
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Identification of novel Nicotinamide Phosphoribosyltransferase (NAMPT) inhibitors using computational approaches by Kesherwani, Manish, Raghavan, Sriram, Gunasekaran, Krishnasamy, Velmurugan, Devadasan

“…Nicotinamide Phosphoribosyltransferase (NAMPT) is a rate-limiting enzyme in the biosynthesis of NAD. Cancer cells have elevated poly [ADP-Ribose] polymerase 1…”
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Digital forensic research: current state of the art by Raghavan, Sriram

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Evolving a communication hierarchy on coordinated tasks using adaptive mobile agents by Raghavan, Sriram, Raghavan, S. V.

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Managing risks of market price uncertainty for a microgrid operation by Raghavan, Sriram

“…After deregulation of electricity in the United States, the day-ahead and real-time markets allow load serving entities and generation companies to bid and…”
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Eliciting file relationships using metadata based associations for digital forensics by Raghavan, Sriram, Raghavan, S. V.

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Analytics using metadata associations for digital investigations by Raghavan, Sriram, Raghavan, S. V.

“…Rapid advancements in technology coupled with drastic reduction in cost of storage have resulted in tremendous increase in the volumes of stored data. As a…”
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