Search Results - "Raggio, C L"

Clinical, Genetic and Environmental Factors Associated with Congenital Vertebral Malformations by Giampietro, P.F., Raggio, C.L., Blank, R.D., McCarty, C., Broeckel, U., Pickart, M.A.

“…Congenital vertebral malformations (CVM) pose a significant health problem because they can be associated with spinal deformities, such as congenital scoliosis…”
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An analysis of PAX1 in the development of vertebral malformations by Giampietro, PF, Raggio, CL, Reynolds, CE, Shukla, SK, McPherson, E, Ghebranious, N, Jacobsen, FS, Kumar, V, Faciszewski, T, Pauli, RM, Rasmussen, K, Burmester, JK, Zaleski, C, Merchant, S, David, D, Weber, JL, Glurich, I, Blank, RD

“…Due to the sporadic occurrence of congenital vertebral malformations, traditional linkage approaches to identify genes associated with human vertebral…”
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Fourier transform infrared imaging spectroscopy (FT-IRIS) of mineralization in bisphosphonate-treated oim/oim mice by Camacho, N P, Carroll, P, Raggio, C L

“…Fourier transform infrared microscopy (FT-IRM) and imaging spectroscopy (FT-IRIS) are increasingly used to analyze the molecular components of mineralized…”
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The Material Basis for Reduced Mechanical Properties in oim Mice Bones by Camacho, Nancy P., Hou, Lindy, Toledano, Talya R., Ilg, W. Alex, Brayton, Cory F., Raggio, Cathleen L., Root, Leon, Boskey, Adele L.

“…Osteogenesis imperfecta (OI), a heritable disease caused by molecular defects in type I collagen, is characterized by skeletal deformities and brittle bones…”
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A controlled study of the effects of alendronate in a growing mouse model of osteogenesis imperfecta by Camacho, N P, Raggio, C L, Doty, S B, Root, L, Zraick, V, Ilg, W A, Toledano, T R, Boskey, A L

“…Recent studies have reported that bisphosphonates reduce fracture incidence and improve bone density in children with osteogenesis imperfecta (OI). However,…”
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Congenital and Idiopathic Scoliosis: Clinical and Genetic Aspects by Giampietro, Philip F, Blank, Robert D, Raggio, Cathleen L, Merchant, Sajid, Jacobsen, F Stig, Faciszewski, Thomas, Shukla, Sanjay K, Greenlee, Anne R, Reynolds, Cory, Schowalter, David B

“…Genetic and environmental factors influencing spinal development in lower vertebrates are likely to play a role in the abnormalities associated with human…”
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A genomic approach to scoliosis pathogenesis by Blank, R D, Raggio, C L, Giampietro, P F, Camacho, N P

“…Genetic predisposition contributes to scoliosis in humans. Two syndromes of primary scoliosis occur — congenital scoliosis, which presents at birth, often…”
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Identification of the oim mutation by dye terminator chemistry combined with automated direct DNA sequencing by Camacho, N P, Dow, D, Toledano, T R, Buckmeyer, J K, Gertner, J M, Brayton, C F, Raggio, C L, Root, L, Boskey, A L

“…The homozygous oim/oim mouse, a model of moderate-to-severe human osteogenesis imperfecta, contains a G-nucleotide deletion in the Cola-2 gene (the murine pro…”
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Synteny-defined candidate genes for congenital and idiopathic scoliosis by Giampietro, Philip F., Raggio, Cathleen L., Blank, Robert D.

“…Idiopathic scoliosis (IS) is a common but poorly understood syndrome. Congenital scoliosis (CS) is less common but comparably unexplored. Previous studies…”
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In vivo hydroxyapatite formation induced by lipids by Raggio, C.L., Boyan, B.D., Boskey, Adele L.

“…Proteolipids and complexed acidic phospholipids that cause in vitro hydroxyapatite formation, similarly cause hydroxyapatite deposition in 10‐μ pore Millipore…”
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Risedronate in children with osteogenesis imperfecta: a randomised, double-blind, placebo-controlled trial by Bishop, Nick, Prof, Adami, Silvano, MD, Ahmed, S Faisal, MD, Antón, Jordi, MD, Arundel, Paul, MD, Burren, Christine P, MD, Devogelaer, Jean-Pierre, MD, Hangartner, Thomas, PhD, Hosszú, Eva, MD, Lane, Joseph M, MD, Lorenc, Roman, MD, Mäkitie, Outi, MD, Munns, Craig F, MD, Paredes, Ana, MD, Pavlov, Helene, MD, Plotkin, Horacio, MD, Raggio, Cathleen L, MD, Reyes, Maria Loreto, MD, Schoenau, Eckhard, MD, Semler, Oliver, MD, Sillence, David O, MD, Steiner, Robert D, MD

“…Summary Background Children with osteogenesis imperfecta are often treated with intravenous bisphosphonates. We aimed to assess the safety and efficacy of…”
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Changes in the bone tissue lipids in persons with steroid- and alcohol-induced osteonecrosis by Boskey, A L, Raggio, C L, Bullough, P G, Kinnett, J G

“…The lipids associated with osteonecrotic bone have a higher cholesterol content than those associated with normal (nondiseased) or osteoarthritic bone. A study…”
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The Effect of Stontium Ranelate on Fracture Reduction in Osteogenesis Imperfecta is Comparable to Recent Bisphosphonate Data by Raggio, Cathleen L, Pleshko, Nancy, Boskey, Adele L

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Alendronate Treatment of the Brtl Osteogenesis Imperfecta Mouse Improves Femoral Geometry and Load Response Before Fracture but Decreases Predicted Material Properties and Has Detrimental Effects on Osteoblasts and Bone Formation by Uveges, Thomas E, Kozloff, Kenneth M, Ty, Jennifer M, Ledgard, Felicia, Raggio, Cathleen L, Gronowicz, Gloria, Goldstein, Steven A, Marini, Joan C

“…Long courses of bisphosphonates are widely administered to children with osteogenesis imperfecta (OI), although bisphosphonates do not block mutant collagen…”
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Osteogenesis imperfecta: potential therapeutic approaches by Rousseau, Maxime, Retrouvey, Jean-Marc

“…Osteogenesis imperfecta (OI) is a genetic disorder that is usually caused by disturbed production of collagen type I. Depending on its severity in the patient,…”
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A Multicenter Observational Cohort Study to Evaluate the Effects of Bisphosphonate Exposure on Bone Mineral Density and Other Health Outcomes in Osteogenesis Imperfecta by Bains, Jaskaran S, Carter, Erin M, Citron, Kate P, Boskey, Adele L, Shapiro, Jay R, Steiner, Robert D, Smith, Peter A, Bober, Michael B, Hart, Tracy, Cuthbertson, David, Krischer, Jeff, Byers, Peter H, Pepin, Melanie, Durigova, Michaela, Glorieux, Francis H, Rauch, Frank, Sliepka, Joseph M, Sutton, V Reid, Lee, Brendan, Nagamani, Sandesh CS, Raggio, Cathleen L

“…Osteogenesis imperfecta (OI) is characterized by low bone mass and bone fragility. Using data from a large cohort of individuals with OI from the Osteogenesis…”
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A Missense T(Brachyury) Mutation Contributes to Vertebral Malformations by Ghebranious, Nader, Blank, Robert D, Raggio, Cathleen L, Staubli, Justin, McPherson, Elizabeth, Ivacic, Lynn, Rasmussen, Kristen, Jacobsen, F Stig, Faciszewski, Thomas, Burmester, James K, Pauli, Richard M, Boachie‐Adjei, Oheneba, Glurich, Ingrid, Giampietro, Philip F

“…No major susceptibility genes for sporadically occurring congenital vertebral malformations (CVM) in humans have been identified to date. Body patterning genes…”
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Differential effects of alendronate treatment on bone from growing osteogenesis imperfecta and wild-type mouse by Misof, Barbara M., Roschger, Paul, Baldini, Todd, Raggio, Cathleen L., Zraick, Vivien, Root, Leon, Boskey, Adele L., Klaushofer, Klaus, Fratzl, Peter, Camacho, Nancy P.

“…Bisphosphonates have been reported to decrease the number of fractures in children with osteogenesis imperfecta (OI). The current study sought to further…”
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Short Report: An analysis of PAX1 in the development of vertebral malformations by Giampietro, P F, Raggio, CL, Reynolds, CE, Shukla, S K, McPherson, E, Ghebranious, N, Jacobsen, F S, Kumar, V, Faciszewski, T, Pauli, R M, Rasmussen, K, Burmester, J K, Zaleski, C, Merchant, S, David, D, Weber, J L, Glurich, I, Blank, R D

“…Due to the sporadic occurrence of congenital vertebral malformations, traditional linkage approaches to identify genes associated with human vertebral…”
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