Search Results - "Ragazzi, Eugenio"
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The Pentose Phosphate Pathway and Its Involvement in Cisplatin Resistance
Published in International journal of molecular sciences (31-01-2020)“…Cisplatin is the first-line treatment for different types of solid tumors, such as ovarian, testicular, bladder, cervical, head and neck, lung, and esophageal…”
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Mitochondrial Involvement in Cisplatin Resistance
Published in International journal of molecular sciences (10-07-2019)“…Cisplatin is one of the worldwide anticancer drugs and, despite its toxicity and frequent recurrence of resistance phenomena, it still remains the only…”
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Selected Plant-Derived Polyphenols as Potential Therapeutic Agents for Peripheral Artery Disease: Molecular Mechanisms, Efficacy and Safety
Published in Molecules (Basel, Switzerland) (01-10-2022)“…Vascular diseases, such as peripheral artery disease (PAD), are associated with diabetes mellitus and a higher risk of cardiovascular disease and even death…”
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Long-term HbA1c variability and macro-/micro-vascular complications in type 2 diabetes mellitus: a meta-analysis update
Published in Acta diabetologica (01-06-2023)“…Aims The aim of the present study was to evaluate, by means of a meta-analysis approach, whether new available data, appeared on qualified literature, can…”
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Telemedicine and its acceptance by patients with type 2 diabetes mellitus at a single care center during the COVID-19 emergency: A cross-sectional observational study
Published in PloS one (15-02-2023)“…When Italy was placed under lockdown to contain the COVID-19 pandemic from 9 March to 18 May 2020, alternative approaches to delivering care-such as…”
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In silico evaluation of the interaction between ACE2 and SARS-CoV-2 Spike protein in a hyperglycemic environment
Published in Scientific reports (24-11-2021)“…The worse outcome of COVID-19 in people with diabetes mellitus could be related to the non-enzymatic glycation of human ACE2, leading to a more susceptible…”
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Cholesterol Metabolic Reprogramming in Cancer and Its Pharmacological Modulation as Therapeutic Strategy
Published in Frontiers in oncology (24-05-2021)“…Cholesterol is a ubiquitous sterol with many biological functions, which are crucial for proper cellular signaling and physiology. Indeed, cholesterol is…”
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Anti-α-Glucosidase and Antiglycation Activities of α-Mangostin and New Xanthenone Derivatives: Enzymatic Kinetics and Mechanistic Insights through In Vitro Studies
Published in Molecules (Basel, Switzerland) (15-01-2022)“…Diabetes mellitus is characterized by chronic hyperglycemia that promotes ROS formation, causing severe oxidative stress. Furthermore, prolonged hyperglycemia…”
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Clinical Evidence of Interaction between Nutraceutical Supplementation and Platinum-based Chemotherapy
Published in Current medicinal chemistry (01-01-2023)“…Platinum agents, which include cisplatin, oxaliplatin and carboplatin, are chemotherapeutic drugs that represent the first-line treatment for different types…”
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Antiviral effects of Glycyrrhiza species
Published in Phytotherapy research (01-02-2008)“…Historical sources for the use of Glycyrrhiza species include ancient manuscripts from China, India and Greece. They all mention its use for symptoms of viral…”
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Is eGFR Slope a Novel Predictor of Chronic Complications of Type 2 Diabetes Mellitus? A Systematic Review and Meta-Analysis
Published in Journal of diabetes research (17-01-2024)“…Background. Diabetic kidney disease affects approximately 40% of patients with type 2 diabetes mellitus (T2DM) and is associated with an increased risk of…”
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AMBER DROPLETS IN THE SOUTHERN ALPS (NE ITALY): A LINK BETWEEN THEIR OCCURRENCES AND MAIN HUMID EPISODES IN THE TRIASSIC
Published in Rivista italiana di paleontologia e stratigrafia (01-03-2022)“…The Anisian amber from the “Voltzia beds” of the Recoaro area, produced by Voltzia recubariensis, represents the most ancient Triassic amber known so far. The…”
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Something about amber: Fictive temperature and glass transition temperature of extremely old glasses from copal to Triassic amber
Published in Polymer (Guilford) (13-12-2013)“…In previous work we successfully used a stable Dominican amber to investigate the sub-glass transition dynamics of an organic glass with extremely low fictive…”
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Omicron Variant of SARS-CoV-2 Virus: In Silico Evaluation of the Possible Impact on People Affected by Diabetes Mellitus
Published in Frontiers in endocrinology (Lausanne) (07-03-2022)“…The Omicron variant of SARS-CoV-2 (Spike mutant B.1.1.529) carrying more than 30-point mutations in its structure, of which 15 are localized in the…”
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Amber, a Stone of Sun for Ancient Medicines
Published in Acta medico-historica Rigensia (01-12-2016)“…Amber, a gem that has been very appreciated since antiquity, was used also as an amulet and a medicine. All the most outstanding medical treati ses of the past…”
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Arthropods in amber from the Triassic Period
Published in Proceedings of the National Academy of Sciences - PNAS (11-09-2012)“…The occurrence of arthropods in amber exclusively from the Cretaceous and Cenozoic is widely regarded to be a result of the production and preservation of…”
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Effect of a New Formulation of Nutraceuticals as an Add-On to Metformin Monotherapy for Patients with Type 2 Diabetes and Suboptimal Glycemic Control: A Randomized Controlled Trial
Published in Nutrients (01-07-2021)“…The aim of the study was to evaluate the overall biohumoral and metabolic effects of a 12-week add-on therapy consisting of a new nutraceutical formulation…”
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Luteolin and Vernodalol as Bioactive Compounds of Leaf and Root Vernonia amygdalina Extracts: Effects on α-Glucosidase, Glycation, ROS, Cell Viability, and In Silico ADMET Parameters
Published in Pharmaceutics (19-05-2023)“…The aqueous decoctions of (VA) leaves and roots are widely used in traditional African medicine as an antidiabetic remedy. The amount of luteolin and…”
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Anti-diabetic combination therapy with pioglitazone or glimepiride added to metformin on the AGE-RAGE axis: a randomized prospective study
Published in Frontiers in endocrinology (Lausanne) (11-08-2023)“…Introduction The ratio between advanced glycation end products (AGEs) and soluble form of receptor (s-RAGE) has been proposed as a risk marker for renal and…”
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Multiplexed MRM-based proteomics for identification of circulating proteins as biomarkers of cardiovascular damage progression associated with diabetes mellitus
Published in Cardiovascular diabetology (20-01-2024)“…Type 2 diabetes mellitus (T2DM) increases the risk of coronary heart disease (CHD) by 2-4 fold, and is associated with endothelial dysfunction, dyslipidaemia,…”
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