Search Results - "Ragan, T. J"
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The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure
Published in Nature communications (26-06-2020)“…MiDAC is one of seven distinct, large multi-protein complexes that recruit class I histone deacetylases to the genome to regulate gene expression. Despite…”
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Cell-Envelope Remodeling as a Determinant of Phenotypic Antibacterial Tolerance in Mycobacterium tuberculosis
Published in ACS infectious diseases (13-05-2016)“…The mechanisms that lead to phenotypic antibacterial tolerance in bacteria remain poorly understood. We investigate whether changes in NaCl concentration…”
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Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex
Published in Cell reports (Cambridge) (25-02-2020)“…The transcriptional corepressor complex CoREST is one of seven histone deacetylase complexes that regulate the genome through controlling chromatin…”
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Evidence for nitric oxide synthase inhibitor-sensitive and insensitive hippocampal synaptic potentiation
Published in Journal of neurophysiology (01-08-1992)“…1. Nitric oxide (NO) has been proposed as a retrograde messenger, mediating the postsynaptic to presynaptic transfer of the effects of conditioning…”
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Thermodynamically balanced inside‐out (TBIO) PCR‐based gene synthesis: a novel method of primer design for high‐fidelity assembly of longer gene sequences
Published in Nucleic acids research (15-11-2003)“…A novel thermodynamically‐balanced inside‐out (TBIO) method of primer design was developed and compared with a thermodynamically‐balanced conventional (TBC)…”
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The sensitivity of hippocampal long-term potentiation to nitric oxide synthase inhibitors is dependent upon the pattern of conditioning stimulation
Published in Neuroscience (01-12-1993)“…Inhibition of nitric oxide synthase prior to conditioning has been previously found to reduce levels of hippocampal long-term potentiation. In the present…”
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Effects of channel modulators on cloned large-conductance calcium-activated potassium channels
Published in Molecular pharmacology (01-07-1996)“…Through expression of the cloned mouse (mSlo) or human (hSlo) large-conductance (BK) Ca(2+)-activated K+ channel in Xenopus laevis oocytes and HEK 293 cells,…”
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Pharmacology of a mixed 5-hydroxytryptamine1A/dopamine agonist
Published in The Journal of pharmacology and experimental therapeutics (01-03-1994)“…U-67413B (4-hydroxydipropylaminodihydrophenalene) bound with high affinity to both 5-hydroxytryptamine (HT)1A and D2-dopamine (DA) receptor sites. U-67413B…”
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Excitation of noradrenergic cell firing by 5-hydroxytryptamine1A agonists correlates with dopamine antagonist properties
Published in The Journal of pharmacology and experimental therapeutics (01-03-1994)“…The 5-HT1A receptor agonists buspirone, 8-hydroxy-N,N-dipropyl-2-aminotetralin, gepirone and ipsapirone were evaluated for their receptor binding profiles and…”
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10
Achievement motivation and competition: perceptions and responses
Published in Medicine and science in sports (1978)“…This study investigated the influence of achievement motivation (Nach) on how individuals perceive an evaluative competition situation, whether they prefer to…”
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Reduced bicuculline response and GABAA agonist binding in aged rat hippocampus
Published in Neurobiology of aging (01-09-1994)“…Extracellular field recordings from CA1 pyramidal cells in the rat hippocampal slice preparation were used to examine the effects of age on gamma-aminobutyric…”
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SINGLE-DOSE TREATMENT OF ENTEROBIASIS—Use of a New Piperazine-Senna Preparation
Published in California medicine (01-12-1962)“…A preparation combining piperazine and senna was clinically tested among 31 families in which at least one member was found to be positive for enterobiasis by…”
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A Tool for Analyzing Implementation Fidelity of an Integrated Learning System
Published in Educational technology research and development (01-01-2000)“…One way to better understand the difficult instructional issues associated with the integration of computer technology in classrooms is to analyze the…”
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Phenotypic Alteration of a Human BK (hSlo) Channel by hSlobeta Subunit Coexpression: Changes in Blocker Sensitivity, Activation/Relaxation and Inactivation Kinetics, and Protein Kinase A Modulation
Published in The Journal of neuroscience (01-08-1996)“…A human homolog of the large-conductance calcium-activated potassium (BK) channel beta subunit (hSlobeta) was cloned, and its effects on a human BK channel…”
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