Search Results - "Rafols, Pere"
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Gold Nanoparticle-Assisted Black Silicon Substrates for Mass Spectrometry Imaging Applications
Published in ACS nano (23-06-2020)“…Mass spectrometry imaging (MSI) based on matrix-assisted laser desorption ionization (MALDI) is widely used in proteomics. However, matrix-free technologies…”
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Perspective on Multimodal Imaging Techniques Coupling Mass Spectrometry and Vibrational Spectroscopy: Picturing the Best of Both Worlds
Published in Analytical chemistry (Washington) (27-04-2021)“…Studies on complex biological phenomena often combine two or more imaging techniques to collect high-quality comprehensive data directly in situ, preserving…”
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SALDI-MS and SERS Multimodal Imaging: One Nanostructured Substrate to Rule Them Both
Published in Analytical chemistry (Washington) (15-02-2022)“…Imaging techniques based on mass spectrometry or spectroscopy methods inform in situ about the chemical composition of biological tissues or organisms, but…”
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What are we imaging? Software tools and experimental strategies for annotation and identification of small molecules in mass spectrometry imaging
Published in Mass spectrometry reviews (01-09-2023)“…Mass spectrometry imaging (MSI) has become a widespread analytical technique to perform nonlabeled spatial molecular identification. The Achilles' heel of MSI…”
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rMSIannotation: A peak annotation tool for mass spectrometry imaging based on the analysis of isotopic intensity ratios
Published in Analytica chimica acta (01-08-2021)“…Mass spectrometry imaging (MSI) consist of spatially located spectra with thousands of peaks. Only a fraction of these peaks corresponds to unique monoisotopic…”
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Raman2imzML converts Raman imaging data into the standard mass spectrometry imaging format
Published in BMC bioinformatics (09-10-2020)“…Multimodal imaging that combines mass spectrometry imaging (MSI) with Raman imaging is a rapidly developing multidisciplinary analytical method used by a…”
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Unravelling the metabolic alterations of liver damage induced by thirdhand smoke
Published in Environment international (01-01-2021)“…•Exposure to thirdhand smoke largely alters liver metabolism of male mice.•Our multiplatform metabolomics approach provided a wide metabolite annotation.•Mass…”
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Assessing the potential of sputtered gold nanolayers in mass spectrometry imaging for metabolomics applications
Published in PloS one (12-12-2018)“…Mass spectrometry imaging (MSI) is a molecular imaging technique that maps the distribution of molecules in biological tissues with high spatial resolution…”
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Novel automated workflow for spectral alignment and mass calibration in MS imaging using a sputtered Ag nanolayer
Published in Analytica chimica acta (31-08-2018)“…Mass spectrometry imaging (MSI) is a technique that can map analyte spatial distribution directly onto a tissue section. This enables the spatial correlation…”
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Lipidomics Reveals Myocardial Lipid Composition in a Murine Model of Insulin Resistance Induced by a High-Fat Diet
Published in International journal of molecular sciences (26-02-2024)“…Ectopic fat accumulation in non-adipose tissues is closely related to diabetes-related myocardial dysfunction. Nevertheless, the complete picture of the lipid…”
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Signal preprocessing, multivariate analysis and software tools for MA(LDI)‐TOF mass spectrometry imaging for biological applications
Published in Mass spectrometry reviews (01-05-2018)“…Mass spectrometry imaging (MSI) is a label‐free analytical technique capable of molecularly characterizing biological samples, including tissues and cell…”
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rMSIproc: an R package for mass spectrometry imaging data processing
Published in Bioinformatics (01-06-2020)“…Abstract Summary Mass spectrometry imaging (MSI) can reveal biochemical information directly from a tissue section. MSI generates a large quantity of complex…”
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rMSI: an R package for MS imaging data handling and visualization
Published in Bioinformatics (Oxford, England) (01-08-2017)“…R platform provides some packages that are useful to process mass spectrometry imaging (MSI) data; however, none of them provide an easy to use graphical user…”
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rMSIfragment: improving MALDI-MSI lipidomics through automated in-source fragment annotation
Published in Journal of cheminformatics (15-09-2023)“…Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging (MALDI-MSI) spatially resolves the chemical composition of tissues. Lipids are of…”
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rMSIcleanup: an open-source tool for matrix-related peak annotation in mass spectrometry imaging and its application to silver-assisted laser desorption/ionization
Published in Journal of cheminformatics (22-07-2020)“…Mass spectrometry imaging (MSI) has become a mature, widespread analytical technique to perform non-targeted spatial metabolomics. However, the compounds used…”
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Hepatic Lipidomics and Molecular Imaging in a Murine Non-Alcoholic Fatty Liver Disease Model: Insights into Molecular Mechanisms
Published in Biomolecules (Basel, Switzerland) (03-09-2020)“…An imbalance between hepatic fatty acid uptake and removal results in ectopic fat accumulation, which leads to non-alcoholic fatty liver disease (NAFLD). The…”
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Silicon‐Based Laser Desorption Ionization Mass Spectrometry for the Analysis of Biomolecules: A Progress Report
Published in Advanced functional materials (01-11-2019)“…Matrix‐assisted laser desorption/ionization mass spectrometry (MALDI‐MS) is widely used in the biomedical field for the label‐free analysis of molecules such…”
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rMSIKeyIon: An Ion Filtering R Package for Untargeted Analysis of Metabolomic LDI-MS Images
Published in Metabolites (02-08-2019)“…Many MALDI-MS imaging experiments make a case versus control studies of different tissue regions in order to highlight significant compounds affected by the…”
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