Mechanical and Imaging Properties of a Clinical-Grade Kidney Phantom Based on Polydimethylsiloxane and Elastomer

Mechanical and Imaging Properties of a Clinical-Grade Kidney Phantom Based on Polydimethylsiloxane and Elastomer

Medical imaging phantoms are considered critical in mimicking the properties of human tissue for calibration, training, surgical planning, and simulation purposes. Hence, the stability and accuracy of the imaging phantom play a significant role in diagnostic imaging. This study aimed to evaluate the...

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Bibliographic Details
Published in:Polymers Vol. 14; no. 3; p. 535
Main Authors: Kamal, Izdihar, Razak, Hairil Rashmizal Abdul, Abdul Karim, Muhammad Khalis, Mashohor, Syamsiah, Liew, Josephine Ying Chyi, Low, Yiin Jian, Zaaba, Nur Atiqah, Norkhairunnisa, Mazlan, Rafi, Nur Athirah Syima Mohd
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 28-01-2022
MDPI
Subjects:
Anthropomorphism
Atomic properties
Attenuation
Cardiovascular disease
compression strength
Compression tests
Compressive strength
Computed tomography
CT number
Dynamic stability
effective atomic number
Elastomers
Evaluation
Human tissues
imaging properties
Kidney diseases
kidney phantom
Kidneys
Medical imaging
Noise
Polydimethylsiloxane
Quality standards
Radiation
Scanners
Silicone resins
Software
Stability analysis
Tomography
United States > US
effective atomic number
imaging properties
compression strength
CT number
kidney phantom
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Summary:Medical imaging phantoms are considered critical in mimicking the properties of human tissue for calibration, training, surgical planning, and simulation purposes. Hence, the stability and accuracy of the imaging phantom play a significant role in diagnostic imaging. This study aimed to evaluate the influence of hydrogen silicone (HS) and water (H O) on the compression strength, radiation attenuation properties, and computed tomography (CT) number of the blended Polydimethylsiloxane (PDMS) samples, and to verify the best material to simulate kidney tissue. Four samples with different compositions were studied, including samples S1, S2, S3, and S4, which consisted of PDMS 100%, HS/PDMS 20:80, H O/PDMS 20:80, and HS/H O/PDMS 20:40:40, respectively. The stability of the samples was assessed using compression testing, and the attenuation properties of sample S2 were evaluated. The effective atomic number of S2 showed a similar pattern to the human kidney tissue at 1.50 × 10 to 1 MeV. With the use of a 120 kVp X-ray beam, the CT number quantified for S2, as well measured 40 HU, and had the highest contrast-to-noise ratio (CNR) value. Therefore, the S2 sample formulation exhibited the potential to mimic the human kidney, as it has a similar dynamic and is higher in terms of stability as a medical phantom.
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ISSN:2073-4360
2073-4360
DOI:10.3390/polym14030535