Search Results - "Raffi, Hajamohideen"
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Validation of Uromodulin as a Candidate Gene for Human Essential Hypertension
Published in Hypertension (Dallas, Tex. 1979) (01-03-2014)“…A recent genome-wide association study identified a locus on chromosome 16 in the promoter region of the uromodulin (UMOD) gene that is associated with…”
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Activation of the Bumetanide-sensitive Na+,K+,2Cl− Cotransporter (NKCC2) Is Facilitated by Tamm-Horsfall Protein in a Chloride-sensitive Manner
Published in The Journal of biological chemistry (26-08-2011)“…Active transport of NaCl across thick ascending limb (TAL) epithelium is accomplished by Na+,K+,2Cl− cotransporter (NKCC2). The activity of NKCC2 is determined…”
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Tamm-horsfall protein protects against urinary tract infection by proteus mirabilis
Published in The Journal of urology (01-05-2009)“…Proteus mirabilis is a common cause of urinary tract infection. We determined the role of Tamm-Horsfall protein as a host defense factor against the cystitis…”
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Renal effects of Tamm-Horsfall protein (uromodulin) deficiency in mice
Published in American journal of physiology. Renal physiology (01-03-2005)“…The Tamm-Horsfall protein (THP; uromodulin), the dominant protein in normal urine, is produced exclusively in the thick ascending limb of Henle's loop. THP…”
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Tamm-Horsfall protein facilitates catheter associated urinary tract infection
Published in BMC research notes (26-09-2012)“…Urinary catheters are associated, commonly with bacteriuria and frequently with urinary tract infection. Tamm-Horsfall Protein (THP) is urine's most abundant…”
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Tamm-Horsfall protein acts as a general host-defense factor against bacterial cystitis
Published in American journal of nephrology (01-11-2005)“…Tamm-Horsfall protein (THP) is urine's most abundant protein, but its biological function has remained elusive. Recently, THP-deficient (THP(-/-)) mice were…”
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Tamm-Horsfall protein knockout mice have increased stress induced micturition
Published in Neurourology and urodynamics (01-01-2009)Get full text
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