Search Results - "Rafferty, S P"

Responses of alkaline phosphatase activity to phosphorus stress in Daphnia magna by McCarthy, S D S, Rafferty, S P, Frost, P C

“…We examined how alkaline phosphatase (AP) activity within the bodies and in the materials released by the crustacean Daphnia magna responds to variable algal…”
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Design and synthesis of 4H-3,1-benzoxazin-4-ones as potent alternate substrate inhibitors of human leukocyte elastase by Krantz, Allen, Spencer, Robin W, Tam, Tim F, Liak, Teng Jiam, Copp, Leslie J, Thomas, Everton M, Rafferty, Steven P

“…4H-3,1-Benzoxazin-4-ones are alternate substrate inhibitors of the serine proteinase human leukocyte elastase (HL elastase) and form acyl enzyme intermediates…”
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Inhibition of Hemoglobin Expression by Heterologous Production of Nitric Oxide Synthase in the K562 Erythroleukemic Cell Line by Rafferty, Steven P., Domachowske, Joseph B., Malech, Harry L.

“…Recent studies have indicated that nitric oxide may affect iron metabolism through disruption of the iron-sulfur complex of iron regulatory protein-1, a…”
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Nitric Oxide Alters the Expression of γ-Globin, H-Ferritin, and Transferrin Receptor in Human K562 Cells at the Posttranscriptional Level by Domachowske, Joseph B., Rafferty, Steven P., Singhania, Neil, Mardiney, Michael, Malech, Harry L.

“…Cellular iron metabolism is altered during chronic inflammatory states, leading to reticuloendothelial iron sequestration and an associated anemia. To study…”
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Electrochemical, kinetic, and circular dichroic consequences of mutations at position 82 of yeast iso-1-cytochrome c by Rafferty, Steven P, Pearce, Linda L, Barker, Paul D, Guillemette, J. Guy, Kay, Cyril M, Smith, Michael, Mauk, A. Grant

“…Replacement of Phe-82 in yeast iso-1-cytochrome c with Tyr, Leu, Ile, Ser, Ala, and Gly produces a gradation of effects on (1) the reduction potential of the…”
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Electrospray ionization tandem mass spectrometric study of salt cluster ions. Part 1- Investigations of alkali metal chloride and sodium salt cluster ions by Hao, Chunyan, March, Raymond E., Croley, Timothy R., Smith, Jeffrey C., Rafferty, Steven P.

“…Salt cluster ions of alkali metal chlorides ACl (A = Li+, Na+, K+, Rb+ and Cs+) and sodium salts NaB (B = I−, HCOO−, CH3COO−, NO2−, and NO3−), formed by…”
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A Structural Role for Tryptophan 188 of Inducible Nitric Oxide Synthase by Wilson, Derek J., Rafferty, Steven P.

“…All nitric oxide synthase (NOS) isotypes bear a conserved tryptophan that stacks against the proximal face of the heme cofactor. Recently two hyperactive…”
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Endogenously produced nitric oxide increases tumor necrosis factor-α production in transfected human U937 cells by YAN, L, WANG, S, RAFFERTY, S. P, WESLEY, R. A, DANNER, R. L

“…Various functions of human phagocytes are modulated by nitric oxide (NO). We transfected the human U937 monoblastoid cell line with an expression vector…”
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Stoichiometric Arginine Binding in the Oxygenase Domain of Inducible Nitric Oxide Synthase Requires a Single Molecule of Tetrahydrobiopterin per Dimer by Rafferty, Steven P., Boyington, Jeffrey C., Kulansky, Rachel, Sun, Peter D., Malech, Harry L.

“…In addition to its catalytic roles, the nitric oxide synthase (NOS) cofactor tetrahydrobiopterin (H4B) is required for substrate binding and for stabilization…”
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Genetic correction of p67phox deficient chronic granulomatous disease using peripheral blood progenitor cells as a target for retrovirus mediated gene transfer by WEIL, W. M, LINTON, G. F, WHITING-THEOBALD, N, VOWELLS, S. J, RAFFERTY, S. P, LI, F, MALECH, H. L

“…Chronic granulomatous disease (CGD) can result from any of four single gene defects involving the components of the superoxide (O-2) generating phagocyte…”
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Mechanistic and Structural Contributions of Critical Surface and Internal Residues to Cytochrome c Electron Transfer Reactivity by Rafferty, Steven P, Guillemette, J. Guy, Berghuis, Albert M, Smith, Michael, Brayer, Gary D, Mauk, A. Grant

“…The influence of mutations in two conserved regions of yeast iso-1-cytochrome c believed to be critical to the mechanism of cytochrome c electron transfer…”
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Application of the intramolecular Schmidt reaction to the asymmetric synthesis of (-)-indolizidine 209B from pulegone by AUBE, J, RAFFERTY, P. S, MILLIGAN, G. L

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Kinetic Unfolding Mechanism of the Inducible Nitric Oxide Synthase Oxygenase Domain Determined by Time-Resolved Electrospray Mass Spectrometry by Wilson, Derek J, Rafferty, Steven P, Konermann, Lars

“…The inducible nitric oxide synthase core oxygen domain (iNOSCOD) is a homodimeric protein complex of ca. 100 kDa. In this work, the subunit disassembly and…”
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Inhibition of hemoglobin expression by heterologous production of nitric oxide synthase in the K562 erythroleukemic cell line by Rafferty, SP, Domachowske, JB, Malech, HL

“…Recent studies have indicated that nitric oxide may affect iron metabolism through disruption of the iron-sulfur complex of iron regulatory protein-1, a…”
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Role of the Heme Propionates in the Interaction of Heme with Apomyoglobin and Apocytochrome b5 by HUNTER, Christie L., LLOYD, Emma, ELTIS, Lindsay D., RAFFERTY, Steven P., LEE, Hung, SMITH, Michael, MAUK, A. Grant

“…The heme propionate groups of both myoglobin (Mb) and cytochrome b5 form hydrogen bonds with nearby surface amino acids residues that are believed to stabilize…”
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Collisional cooling enhances the ability to observe non-covalent interactions within the inducible nitric oxide synthase oxygenase domain: dimerization, complexation, and dissociation by Smith, Jeffrey C, Siu, K.W.Michael, Rafferty, Steven P

“…The investigation of protein quaternary structure, protein-cofactor, and protein–ligand interactions by mass spectrometry is often limited by the fragility of…”
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Endogenously Produced Nitric Oxide Increases Tumor Necrosis Factor-α Production in Transfected Human U937 Cells by Yan, Liang, Wang, Shuibang, Rafferty, Steven P., Wesley, Robert A., Danner, Robert L.

“…Various functions of human phagocytes are modulated by nitric oxide (NO). We transfected the human U937 monoblastoid cell line with an expression vector…”
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Azide binding and active site dynamics of position-82 variants of ferricytochrome c by Rafferty, Steven P., Srnith, Michael, Mauk, A.Grant

“…Azide binding to wild-type and five position-82 variants of yeast iso-l-ferricytochrome c has been studied by spectrophotometric titrations and stopped-flow…”
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Religion and Greater Ireland: Christianity and Irish Global Networks 1750-1950 [McGill-Queen's Studies in the History of Religion, Series 2, vol. 73] by Rafferty, Oliver P.

“…Irish religious experience could never quite escape the tension produced by Irish political realities. [...]Myrtle Hill, in her chapter on Irish women in…”
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