Search Results - "Rafael Silva-Rocha"
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The private life of environmental bacteria: pollutant biodegradation at the single cell level
Published in Environmental microbiology (01-03-2014)“…Summary Bacteria display considerable cell‐to‐cell heterogeneity in a number of genetic and physiological traits. Stochastic differences in regulatory patterns…”
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The art of vector engineering: towards the construction of next‐generation genetic tools
Published in Microbial biotechnology (01-01-2019)“…Summary When recombinant DNA technology was developed more than 40 years ago, no one could have imagined the impact it would have on both society and the…”
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Chromatin profiling reveals heterogeneity in clinical isolates of the human pathogen Aspergillus fumigatus
Published in PLoS genetics (10-01-2022)“…Invasive Pulmonary Aspergillosis, which is caused by the filamentous fungus Aspergillus fumigatus, is a life-threatening infection for immunosuppressed…”
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4
Transcriptional regulation of central carbon metabolism in Pseudomonas aeruginosa
Published in Microbial biotechnology (01-01-2020)“…Summary Microbes such as Pseudomonas aeruginosa are often challenged by rapidly changing nutritional environments. In order to adapt to these shifts in…”
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Stochasticity of TOL plasmid catabolic promoters sets a bimodal expression regime in Pseudomonas putida mt-2 exposed to m-xylene
Published in Molecular microbiology (01-10-2012)“…Summary The expression dynamics of the catabolic promoters of the TOL plasmid pWW0 has been examined in single cells of Pseudomonas putida mt‐2 exposed to…”
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Pre‐mRNA splicing is modulated by antifungal drugs in the filamentous fungus Neurospora crassa
Published in FEBS open bio (01-04-2016)“…For this study, we sought to identify pre‐mRNA processing events modulated by changes in extracellular pH, inorganic phosphate, and antifungal drugs. We…”
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Recent Progress on Systems and Synthetic Biology Approaches to Engineer Fungi As Microbial Cell Factories
Published in Current genomics (01-04-2016)“…Filamentous fungi are remarkable organisms naturally specialized in deconstructing plant biomass and this feature has a tremendous potential for biofuel…”
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The Standard European Vector Architecture (SEVA): a coherent platform for the analysis and deployment of complex prokaryotic phenotypes
Published in Nucleic acids research (01-01-2013)“…The 'Standard European Vector Architecture' database (SEVA-DB, http://seva.cnb.csic.es) was conceived as a user-friendly, web-based resource and a material…”
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ChiMera: an easy to use pipeline for bacterial genome based metabolic network reconstruction, evaluation and visualization
Published in BMC bioinformatics (30-11-2022)“…Genome-scale metabolic reconstruction tools have been developed in the last decades. They have helped to reconstruct eukaryotic and prokaryotic metabolic…”
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Systems-Wide Dissection of Organic Acid Assimilation in Pseudomonas aeruginosa Reveals a Novel Path To Underground Metabolism
Published in mBio (20-12-2022)“…The human pathogen Pseudomonas aeruginosa (Pa) is one of the most frequent and severe causes of nosocomial infection. This organism is also a major cause of…”
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Galectin-3 impacts Cryptococcus neoformans infection through direct antifungal effects
Published in Nature communications (06-12-2017)“…Cryptococcus neoformans is an encapsulated fungal pathogen that causes cryptococcosis, which is a major opportunistic infection in immunosuppressed…”
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Citrus rootstocks influence the population densities of pest mites
Published in Ciência rural (01-01-2016)“…Citrus are attacked by pest mites such as the citrus rust mite Phyllocoptruta oleivora (Ashmead) (Acari: Eriophyidae) and the spider mite Tetranychus mexicanus…”
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Identification and functional analysis of novel protein-encoding sequences related to stress-resistance
Published in Frontiers in microbiology (28-09-2023)“…Currently, industrial bioproducts are less competitive than chemically produced goods due to the shortcomings of conventional microbial hosts. Thus, is…”
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A toolset of constitutive promoters for metabolic engineering of Rhodosporidium toruloides
Published in Microbial cell factories (29-06-2019)“…Rhodosporidium toruloides is a promising host for the production of bioproducts from lignocellulosic biomass. A key prerequisite for efficient pathway…”
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Seasonal variation of pest mite populations in relation to citrus scion cultivars in northeastern Brazil
Published in Acta agronomica (Palmira) (01-04-2017)“…Pest populations in a given agroecosystem may be influenced by several abiotic and biotic variables, including the host plant cultivar. We compared the…”
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Aspergillus fumigatus protein phosphatase PpzA is involved in iron assimilation, secondary metabolite production, and virulence
Published in Cellular microbiology (01-12-2017)“…Summary Metal restriction imposed by mammalian hosts during an infection is a common mechanism of defence to reduce or avoid the pathogen infection. Metals are…”
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Benchmarking Bacterial Promoter Prediction Tools: Potentialities and Limitations
Published in mSystems (25-08-2020)“…The promoter region is a key element required for the production of RNA in bacteria. While new high-throughput technology allows massively parallel mapping of…”
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The Duality of the MAPK Signaling Pathway in the Control of Metabolic Processes and Cellulase Production in Trichoderma reesei
Published in Scientific reports (08-10-2018)“…In this study, through global transcriptional analysis by RNA-Sequencing, we identified the main changes in gene expression that occurred in two functional…”
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Mining novel cis -regulatory elements from the emergent host Rhodosporidium toruloides using transcriptomic data
Published in Frontiers in microbiology (06-01-2023)“…The demand for robust microbial cell factories that produce valuable biomaterials while resisting stresses imposed by current bioprocesses is rapidly growing…”
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Aspergillus fumigatus High Osmolarity Glycerol Mitogen Activated Protein Kinases SakA and MpkC Physically Interact During Osmotic and Cell Wall Stresses
Published in Frontiers in microbiology (07-05-2019)“…, a saprophytic filamentous fungus, is a serious opportunistic pathogen of mammals and it is the primary causal agent of invasive aspergillosis (IA). Mitogen…”
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