Search Results - "Rafacho, A"

Heterogeneity in the preferential diet of neotropical bats impacts the pancreatic islet mass and α and β cell distribution by Contini, M., Cruz, G.D., Althoff, S.F., Freitas, M.B., Taboga, S.R., Rafacho, A.

“…[Display omitted] •Frugivorous and nectarivorous bats have high islet density.•Insectivorous and hematophagous bats have low islet density.•Hematophagous bat…”
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Comparative study of endocrine pancreatic tissue in bats: Assessing variations among frugivorous, insectivorous, and nectarivorous diets by Contini, M., Beguelini, MR, Ruiz, TFR, Taboga, SR, Rafacho, A.

“…Whether the endocrine pancreas exhibits structural features to couple with dietary patterns is not fully explored. Considering the lack of data comparing…”
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Acute and chronic effects of the organophosphate malathion on the pancreatic α and β cell viability, cell structure, and voltage-gated K+ currents by Martins, J.R.N, Lopes, S., Hurtado, H.N., da Silva, F.N., Villard, D.R., Taboga, S.R., Souza, K.L.A, Quesada, I., Soriano, S., Rafacho, A.

“…Studies indicate that the pesticide malathion may have a role in diabetes. Herein, we determined the effects of different concentrations of malathion on…”
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Morphofunctional alterations in endocrine pancreas of short- and long-term dexamethasone-treated rats by Rafacho, A, Abrantes, J L F, Ribeiro, D L, Paula, F M, Pinto, M E, Boschero, A C, Bosqueiro, J R

“…Long-term dexamethasone therapy may induce peripheral insulin resistance (IR), which in turn elicits increased beta-cell function and proliferation. However,…”
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Glucose homoeostasis in rats exposed to acute intermittent hypoxia by Rafacho, A., Gonçalves-Neto, L. M., Ferreira, F. B. D., Protzek, A. O. P., Boschero, A. C., Nunes, E. A., Zoccal, D. B.

“…Aim Chronic exposure to intermittent hypoxia commonly induces the activation of sympathetic tonus and the disruption of glucose homoeostasis. However, the…”
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Higher insulin sensitivity and impaired insulin secretion in cachetic solid ehrlich tumour-bearing mice by Violato, N M, Rafacho, A, Boschero, A C, Bosqueiro, J R

“…Insulin secretion is mainly regulated by blood glucose concentration. On the other hand, changes in peripheral insulin sensitivity induce compensatory…”
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adaptive compensations in endocrine pancreas from glucocorticoid-treated rats are reversible after the interruption of treatment by Rafacho, A, Quallio, S, Ribeiro, D.L, Taboga, S.R, Paula, F.M.M, Boschero, A.C, Bosqueiro, J.R

“…Glucocorticoid administration induces insulin resistance (IR) and enhances islet mass and insulin secretion in rodents and humans. Here, we analysed whether…”
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Insulin and glucose sensitivity, insulin secretion and β-cell distribution in endocrine pancreas of the fruit bat Artibeus lituratus by Protzek, A.O.P., Rafacho, A., Viscelli, B.A., Bosqueiro, J.R., Cappelli, A.P., Paula, F.M.M., Boschero, A.C., Pinheiro, E.C.

“…The fruit bat Artibeus lituratus absorbs large amounts of glucose in short periods of time and maintains normoglycemia even after a prolonged starvation…”
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Reduced pancreatic beta-cell mass is associated with decreased FoxO1 and Erk1/2 protein phosphorylation in low-protein malnourished rats by Rafacho, A, Giozzet, V A G, Boschero, A C, Abrantes, J L F, Cestari, T M, Carneiro, E M, Bosqueiro, J R

“…A low-protein diet leads to functional and structural pancreatic islet alterations, including islet hypotrophy. Insulin-signaling pathways are involved in…”
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Dexamethasone-induced insulin resistance is associated with increased connexin 36 mRNA and protein expression in pancreatic rat islets by Rafacho, A, Roma, L P, Taboga, S R, Boschero, A C, Bosqueiro, J R

“…Augmented glucose-stimulated insulin secretion (GSIS) is an adaptive mechanism exhibited by pancreatic islets from insulin-resistant animal models. Gap…”
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Cellular changes in the prostatic stroma of glucocorticoid-treated rats by Ribeiro, D. L., Rafacho, A., Bosqueiro, J. R., Taboga, S. R., Góes, R. M.

“…Glucocorticoid hormones (GCs) have been widely used for the treatment of prostate cancer because of their inhibitory property against tumour growth. However,…”
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Glucocorticoid treatment and endocrine pancreas function: implications for glucose homeostasis, insulin resistance and diabetes by Rafacho, Alex, Ortsäter, Henrik, Nadal, Angel, Quesada, Ivan

“…Glucocorticoids (GCs) are broadly prescribed for numerous pathological conditions because of their anti-inflammatory, antiallergic and immunosuppressive…”
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Mixed-meal test reveals a worsen phenotypic flexibility correlated to central adiposity in clinically healthy young males by Corrêa, C.R., Filipini, R.E., Mazera, M.S., Rafacho, A., Nunes, E.A.

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Age- and gender-related changes in glucose homeostasis in glucocorticoid-treated rats by dos Santos, Cristiane, Ferreira, Francielle Batista D, Gonçalves-Neto, Luiz M, Taboga, Sebastião Roberto, Boschero, Antonio Carlos, Rafacho, Alex

“…The disruption to glucose homeostasis upon glucocorticoid (GC) treatment in adult male rats has not been fully characterized in older rats or in females. Thus,…”
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Liraglutide counteracts obesity and glucose intolerance in a mouse model of glucocorticoid-induced metabolic syndrome by Fransson, Liselotte, Dos Santos, Cristiane, Wolbert, Petra, Sjöholm, Ake, Rafacho, Alex, Ortsäter, Henrik

“…Glucocorticoid excess is commonly associated with diabetogenic effects, including insulin resistance and glucose intolerance. The effects of the long-term…”
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Insulin and glucose sensitivity, insulin secretion and b-cell distribution in endocrine pancreas of the fruit bat Artibeus lituratus by Protzek, AOP, Rafacho, A, Viscelli, BA, Bosqueiro, J R, Cappelli, AP, Paula, FMM, Boschero, A C, Pinheiro, E C

“…The fruit bat Artibeus lituratus absorbs large amounts of glucose in short periods of time and maintains normoglycemia even after a prolonged starvation…”
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