Search Results - "Raeve, Hendrik De"

The role of DNA damage and repair in decitabine-mediated apoptosis in multiple myeloma by Maes, Ken, De Smedt, Eva, Lemaire, Miguel, De Raeve, Hendrik, Menu, Eline, Van Valckenborgh, Els, McClue, Steve, Vanderkerken, Karin, De Bruyne, Elke

“…DNA methyltransferase inhibitors (DNMTi) and histone deacetylase inhibitors (HDACi) are under investigation for the treatment of cancer, including the plasma…”
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Zoledronic Acid Treatment of 5T2MM‐Bearing Mice Inhibits the Development of Myeloma Bone Disease: Evidence for Decreased Osteolysis, Tumor Burden and Angiogenesis, and Increased Survival by Croucher, Peter I, De Raeve, Hendrik, Perry, Mark J, Hijzen, Anja, Shipman, Claire M, Lippitt, Jennifer, Green, Jonathan, Van Marck, Eric, Van Camp, Ben, Vanderkerken, Karin

“…Multiple myeloma is characterized by the growth of plasma cells in the bone marrow and the development of osteolytic bone disease. Myeloma cells are found…”
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Targeting angiogenesis in multiple myeloma by the VEGF and HGF blocking DARPin® protein MP0250: a preclinical study by Rao, Luigia, De Veirman, Kim, Giannico, Donato, Saltarella, Ilaria, Desantis, Vanessa, Frassanito, Maria Antonia, Solimando, Antonio Giovanni, Ribatti, Domenico, Prete, Marcella, Harstrick, Andreas, Fiedler, Ulrike, De Raeve, Hendrik, Racanelli, Vito, Vanderkerken, Karin, Vacca, Angelo

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Metachronous metastasis of renal cell carcinoma to the urinary bladder: a case report by De Groote, Ruben, Larcher, Alessandro, Goossens, Marijn, Hendrik, De Raeve, Kris, Van Der Steen, De Coninck, Vincent, De Naeyer, Geert, Schatteman, Peter, D’Hondt, Frederiek, Mottrie, Alexandre

“…We report a case of intravesical metastasis of a clear cell renal cell carcinoma. In renal cell carcinoma 16% of patients present with metastatic disease…”
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Exosomes play a role in multiple myeloma bone disease and tumor development by targeting osteoclasts and osteoblasts by Faict, Sylvia, Muller, Joséphine, De Veirman, Kim, De Bruyne, Elke, Maes, Ken, Vrancken, Louise, Heusschen, Roy, De Raeve, Hendrik, Schots, Rik, Vanderkerken, Karin, Caers, Jo, Menu, Eline

“…Progression of multiple myeloma (MM) is largely dependent on the bone marrow (BM) microenvironment wherein communication through different factors including…”
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Granulocytic myeloid-derived suppressor cells promote angiogenesis in the context of multiple myeloma by Binsfeld, Marilène, Muller, Joséphine, Lamour, Virginie, De Veirman, Kim, De Raeve, Hendrik, Bellahcène, Akeila, Van Valckenborgh, Els, Baron, Frédéric, Beguin, Yves, Caers, Jo, Heusschen, Roy

“…Multiple myeloma (MM) is a plasma cell malignancy characterized by the accumulation of tumor cells in the bone marrow (BM) and is associated with…”
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ER stress arm XBP1s plays a pivotal role in proteasome inhibition-induced bone formation by Zhang, Dan, De Veirman, Kim, Fan, Rong, Jian, Qiang, Zhang, Yuchen, Lei, Li, Evans, Holly, Wang, Yanmeng, Lei, Lei, Wang, Baiyan, Williamson, Ramone A, Chantry, Andrew, He, Pengcheng, Li, Ang, De Raeve, Hendrik, Vanderkerken, Karin, He, Aili, Hu, Jinsong

“…Bone destruction is a hallmark of multiple myeloma (MM). It has been reported that proteasome inhibitors (PIs) can reduce bone resorption and increase bone…”
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The anaphase-promoting complex/cyclosome: a new promising target in diffuse large B-cell lymphoma and mantle cell lymphoma by Maes, Anke, Maes, Ken, De Raeve, Hendrik, De Smedt, Eva, Vlummens, Philip, Szablewski, Vanessa, Devin, Julie, Faict, Sylvia, De Veirman, Kim, Menu, Eline, Offner, Fritz, Spaargaren, Marcel, Moreaux, Jérôme, Vanderkerken, Karin, Van Valckenborgh, Els, De Bruyne, Elke

“…Background The aggressive B-cell non-Hodgkin lymphomas diffuse large B-cell lymphoma (DLBCL) and mantle cell lymphoma (MCL) are characterised by a high…”
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Synergistic induction of apoptosis in multiple myeloma cells by bortezomib and hypoxia-activated prodrug TH-302, in vivo and in vitro by Hu, Jinsong, Van Valckenborgh, Els, Xu, Dehui, Menu, Eline, De Raeve, Hendrik, De Bruyne, Elke, De Bryune, Elke, Xu, Song, Van Camp, Ben, Handisides, Damian, Hart, Charles P, Vanderkerken, Karin

“…Recently, we showed that hypoxia is a critical microenvironmental factor in multiple myeloma, and that the hypoxia-activated prodrug TH-302 selectively targets…”
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Changing concepts of diagnostic criteria of myeloproliferative disorders and the molecular etiology and classification of myeloproliferative neoplasms: from Dameshek 1950 to Vainchenker 2005 and beyond by Michiels, Jan Jacques, Berneman, Zwi, Schroyens, Wilfried, De Raeve, Hendrik

“…The Polycythemia Vera Study Group (PVSG) and WHO classifications distinguished the Philadelphia (Ph(1)) chromosome-positive chronic myeloid leukemia from the…”
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Role of CCR1 and CCR5 in homing and growth of multiple myeloma and in the development of osteolytic lesions: a study in the 5TMM model by Menu, Eline, De Leenheer, Evy, De Raeve, Hendrik, Coulton, Les, Imanishi, Takeshi, Miyashita, Kazuyuki, Van Valckenborgh, Els, Van Riet, Ivan, Van Camp, Ben, Horuk, Richard, Croucher, Peter, Vanderkerken, Karin

“…Multiple myeloma (MM) is a plasma cell malignancy, characterized by the localization of the MM cells in the bone marrow (BM), where they proliferate and induce…”
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Reproducibility of Histologic Classification in Nonfibrotic Myeloproliferative Neoplasia by KOOPMANS, Suzanne M, BOT, Freek J, LAM, King H, VAN MARION, Arienne M. W, DE RAEVE, Hendrik, HEBEDA, Konnie M

“…Early phases of polycythemia vera, essential thrombocythemia, and primary myelofibrosis (PMF) can be difficult to distinguish by morphologic studies alone…”
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Targeting the IGF‐1R using picropodophyllin in the therapeutical 5T2MM mouse model of multiple myeloma: Beneficial effects on tumor growth, angiogenesis, bone disease and survival by Menu, Eline, Jernberg‐Wiklund, Helena, De Raeve, Hendrik, De Leenheer, Evy, Coulton, Les, Gallagher, Orla, Van Valckenborgh, Els, Larsson, Olle, Axelson, Magnus, Nilsson, Kenneth, Van Camp, Ben, Croucher, Peter, Vanderkerken, Karin

“…During the last decade, a central role for insulin‐like growth factor 1 (IGF‐1) in the pathophysiology of multiple myeloma (MM) has been well established…”
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Extension of 2016 World Health Organization (WHO) Classification into a New Set of Clinical, Laboratory, Molecular, and Pathological Criteria for the Diagnosis of Myeloproliferative Neoplasms: From Dameshek to Vainchenker, Green, and Kralovics by Michiels, Jan Jacques, De Raeve, Hendrik, Valster, Francisca, Potters, Vincent, Kim, Yonggoo, Kim, Myungshin

“…Improved Clinical, Laboratory, Molecular, and Pathological (CLMP) 2017 criteria for myeloproliferative neoplasms (MPN) define the JAK2V617F trilinear MPNs as a…”
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Clinical and laboratory features, pathobiology of platelet-mediated thrombosis and bleeding complications, and the molecular etiology of essential thrombocythemia and polycythemia vera: therapeutic implications by Michiels, Jan J, Berneman, Zwi, Van Bockstaele, Dirk, van der Planken, Marc, De Raeve, Hendrik, Schroyens, Wilfried

“…Microvascular disturbances in essential thrombocythemia (ET) and polycythemia vera (PV), including erythromelalgia, and atypical and typical transient…”
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An unexpected complication of chronic myelomonocytic leukemia: severe renal failure due to malignant tubulo-interstitial cell infiltration by Spapen, Jerrold, Fostier, Karel, De Raeve, Hendrik, Janssens, Peter, Spapen, Herbert

“…Acute renal failure may complicate the course of a hematologic malignancy but is a highly unusual finding in patients with chronic myelomonocytic leukemia…”
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WHO bone marrow features and European clinical, molecular, and pathological (ECMP) criteria for the diagnosis of myeloproliferative disorders by Michiels, Jan Jacques, De Raeve, Hendrik, Hebeda, Konnie, Lam, King H, Berneman, Zwi, Schroyens, Wilfried, Schwarz, Jiri

“…Abstract The bone marrow criteria defined by the World Health Organization (WHO) are based on characteristic increase and clustering of morphologically…”
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Eosinophilic Fasciitis: an Atypical Presentation of a Rare Disease by Poradosu, Sabrina, Vanderlinden, Esther, Michotte, Alex, De Raeve, Hendrik, Allard, Sabine

“…Objectives: We report an atypical presentation of eosinophilic fasciitis and provide a concise overview of the literature. Materials and Methods: Clinical and…”
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The European Clinical, Molecular, and Pathological (ECMP) Criteria and the 2007/2008 Revisions of the World Health Organization for the Diagnosis, Classification, and Staging of Prefibrotic Myeloproliferative Neoplasms Carrying the JAK2V617F Mutation by Michiels, Jan Jacques, Kate, Fibo Ten, Lam, King H., Schroyens, Wilfried, Berneman, Zwi, De Raeve, Hendrik

“…Objective: The prefibrotic stages of JAK2V617F essential thrombocythemia (ET) and JAK2V617F polycythemia vera (PV) can easily be diagnosed clinically without…”
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Recurrent Myasthenia Gravis Due to a Pleural Implant 3 Years After Radical Thymectomy by Heyman, Stijn R.G., MD, De Raeve, Hendrik, MD, PhD, Mercelis, Rudy, MD, PhD, De Pooter, Christel, MD, PhD, Van Schil, Paul, MD, PhD

“…Although recurrence of a thymoma is rare, pleural dissemination or local relapses have been described. We present a patient who underwent complete thymectomy…”
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