Search Results - "Raes, G."

Antigen-presenting cell-targeted lentiviral vectors do not support the development of productive T-cell effector responses: implications for in vivo targeted vaccine delivery by Goyvaerts, C, De Vlaeminck, Y, Escors, D, Lienenklaus, S, Keyaerts, M, Raes, G, Breckpot, K

“…Targeting transgene expression specifically to antigen-presenting cells (APCs) has been put forward as a promising strategy to direct the immune system towards…”
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Evaluation of single domain antibodies as nuclear tracers for imaging of the immune checkpoint receptor human lymphocyte activation gene-3 in cancer by Lecocq, Q., Debie, P., Puttemans, J., Awad, R. M., De Beck, L., Ertveldt, T., De Vlaeminck, Y., Goyvaerts, C., Raes, G., Keyaerts, M., Breckpot, K., Devoogdt, N.

“…Recent advancements in the field of immune-oncology have led to a significant increase in life expectancy of patients with diverse forms of cancer, such as…”
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Development of the Nanobody display technology to target lentiviral vectors to antigen-presenting cells by Goyvaerts, C, De Groeve, K, Dingemans, J, Van Lint, S, Robays, L, Heirman, C, Reiser, J, Zhang, X-Y, Thielemans, K, De Baetselier, P, Raes, G, Breckpot, K

“…Lentiviral vectors (LVs) provide unique opportunities for the development of immunotherapeutic strategies, as they transduce a variety of cells in situ ,…”
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Claudin-1, Claudin-2 and Claudin-11 Genes Differentially Associate with Distinct Types of Anti-inflammatory Macrophages In vitro and with Parasite- and Tumour-elicited Macrophages In vivo by Van den Bossche, J., Laoui, D., Morias, Y., Movahedi, K., Raes, G., De Baetselier, P., Van Ginderachter, J. A.

“…Macrophages altered by various Th2‐associated and anti‐inflammatory mediators – including IL‐4 and IL‐13 [inducing alternatively activated macrophages (AAMs)],…”
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Development of LAG-3 nanobodies as potent cancer imaging tracers by Lecocq, Q., Awad, R.M., Zeven, K., De Vlaeminck, Y., de Mey, W., Debie, P., Puttemans, J., Goyvaerts, C., Raes, G., Keyaerts, M., Devoogdt, N., Breckpot, K.

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Heterogeneity of macrophage activation in fish by Forlenza, Maria, Fink, Inge R., Raes, Geert, Wiegertjes, Geert F.

“…In this review, we focus on four different activation states of fish macrophages. In vitro, stimulation with microbial ligands induces the development of…”
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Estimation of the size of the chromosome 17p11.2 duplication in Charcot-Marie-Tooth neuropathy type 1a (CMT1a) by RAEYMAEKERS, P, TIMMERMAN, V, NELIS, E, VAN HUL, W, DE JONGHE, P, MARTIN, J.-J, VAN BROECKHOVEN, C

“…We aimed to estimate the size of the duplication using additional polymorphic DNA markers located in 17p11.2-p12. Two other 17p11.2 markers, pVAW412R3…”
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Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells by Raes, Geert, Van den Bergh, Rafaël, De Baetselier, Patrick, Ghassabeh, Gholamreza Hassanzadeh, Scotton, Chris, Locati, Massimo, Mantovani, Alberto, Sozzani, Silvano

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A locus-specific mutation database for the neural cell adhesion molecule L1CAM (Xq28) by Van Camp, Guy, Fransen, Erik, Vits, Lieve, Raes, Geert, Willems, Patrick J.

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Alternatively activated macrophages during parasite infections by Noël, Wim, Raes, Geert, Hassanzadeh Ghassabeh, Gholamreza, De Baetselier, Patrick, Beschin, Alain

“…Depending on the cytokine environment, macrophages can differentiate into distinct subsets that perform specific immunological roles. In this regard, the…”
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Alternatively activated macrophages in protozoan infections by Raes, Geert, Beschin, Alain, Ghassabeh, Gholamreza Hassanzadeh, De Baetselier, Patrick

“…A type 1 cytokine-dependent pro-inflammatory response inducing classically activated macrophages is crucial for parasite control during protozoan infections…”
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Active antitumor immunotherapy, with or without B7-mediated costimulation, increases tumor progression in an immunogenic murine T cell lymphoma model by Raes, G, Van Ginderachter, J, Liu, Y Q, Brys, L, Thielemans, K, De Baetselier, P, Geldhof, A

“…BW-Sp3 is a BW-5147-derived T cell lymphoma with limited immunogenicity since, despite regression of the majority of subcutaneous tumors, an important fraction…”
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Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages by Raes, Geert, De Baetselier, Patrick, Noël, Wim, Beschin, Alain, Brombacher, Frank, Hassanzadeh Gh, Gholamreza

“…Alternatively activated macrophages (aaMφ) display molecular and biological characteristics that differ from those of classically activated macrophages (caMφ)…”
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Effects of altered antigen processing on T-cell responses toward murine T-lymphomas by Raes, G, Van Ginderachter, J, Devoogdt, N, Geldhof, A, De Baetselier, P

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Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation by Raes, G, Brys, L, Dahal, B K, Brandt, J, Grooten, J, Brombacher, F, Vanham, G, Noel, W, Bogaert, P, Boonefaes, T, Kindt, A, Van den Bergh, R, Leenen, PJM, De Baetselier, P, Ghassabeh, G H

“…Molecular markers, especially surface markers associated with type II, cytokine‐dependent, alternatively activated macrophages (aaMF), remain scarce. Besides…”
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Reactive Oxygen Species and 12/15-Lipoxygenase Contribute to the Antiproliferative Capacity of Alternatively Activated Myeloid Cells Elicited during Helminth Infection by Brys, Lea, Beschin, Alain, Raes, Geert, Ghassabeh, Gholamreza Hassanzadeh, Noel, Wim, Brandt, Jef, Brombacher, Frank, Baetselier, Patrick De

“…Understanding the role of CD11b(+)GR-1(+) myeloid suppressor cells in the immune suppression and immunoregulation associated with a variety of diseases may…”
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The Man and Machine Robot Orchestra at Logos by Maes, Laura, Raes, Godfried-Willem, Rogers, Troy

“…This article provides an overview of the various automata of the Man and Machine robot orchestra found at the Logos Foundation in Ghent, Belgium. The…”
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African trypanosomosis: From immune escape and immunopathology to immune intervention by Stijlemans, Benoît, Guilliams, Martin, Raes, Geert, Beschin, Alain, Magez, Stefan, De Baetselier, Patrick

“…African trypanosomes can cause prolonged chronic infections through a mechanism of antigen variation whereby they manipulate the humoral immune system of their…”
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Nitric Oxide-Independent CTL Suppression during Tumor Progression: Association with Arginase-Producing (M2) Myeloid Cells by Liu, Yuanqing, Van Ginderachter, Jo A, Brys, Lea, De Baetselier, Patrick, Raes, Geert, Geldhof, Anja B

“…Most of the mice bearing a s.c. BW-Sp3 lymphoma tumor mount a CD8(+) T cell-mediated response resulting in tumor regression. Nonetheless, tumor progression…”
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The dermal microenvironment induces the expression of the alternative activation marker CD301/mMGL in mononuclear phagocytes, independent of IL-4/IL-13 signaling by Dupasquier, Marcel, Stoitzner, Patrizia, Wan, Hui, Cerqueira, Denise, Van Oudenaren, Adri, Voerman, Jane S. A., Denda‐Nagai, Kaori, Irimura, Tatsuro, Raes, Geert, Romani, Nikolaus, Leenen, Pieter J. M.

“…Recently, we have shown that mononuclear phagocytes comprise the majority of interstitial cells in the mouse dermis, as indicated by their phenotypic and…”
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