Search Results - "Raemdonck, K."

Challenges and strategies for the delivery of biologics to the cornea by Wels, M., Roels, D., Raemdonck, K., De Smedt, S.C., Sauvage, F.

“…Biologics, like peptides, proteins and nucleic acids, have proven to be promising drugs for the treatment of numerous diseases. However, besides the off label…”
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Anxiety and depression risk in patients with allergic rhinitis: a systematic review and meta-analysis by Rodrigues, J., Franco-Pego, F., Sousa-Pinto, B., Bousquet, J., Raemdonck, K., Vaz, R.

“…Background: Allergic diseases appear to be associated with mood disorders. However, particularly regarding allergic rhinitis (AR), such association has not…”
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Prolonged gene silencing by combining siRNA nanogels and photochemical internalization by Raemdonck, K., Naeye, B., Høgset, A., Demeester, J., De Smedt, Stefaan C.

“…Small interfering RNAs (siRNAs) show potential for the treatment of a wide variety of pathologies with a known genetic origin through sequence-specific gene…”
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Autocrine CCL2, CXCL4, CXCL9 and CXCL10 signal in retinal endothelial cells and are enhanced in diabetic retinopathy by Nawaz, M.I., Van Raemdonck, K., Mohammad, G., Kangave, D., Van Damme, J., Abu El-Asrar, A.M., Struyf, S.

“…This study aimed at examining the presence and role of chemokines (angiogenic CCL2/MCP-1 and angiostatic CXCL4/PF-4, CXCL9/Mig, CXCL10/IP-10) in proliferative…”
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PEGylation of biodegradable dextran nanogels for siRNA delivery by Naeye, B., Raemdonck, K., Remaut, K., Sproat, B., Demeester, J., De Smedt, S.C.

“…Delivering intact small interfering RNA (siRNA) into the cytoplasm of targeted cells in vivo is considered a major obstacle in the development of clinically…”
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House dust mite induces direct airway inflammation in vivo: implications for future disease therapy? by DE ALBA, J, RAEMDONCK, K, DEKKAK, A, COLLINS, M, WONG, S, NIALS, A. T, KNOWLES, R. G, BELVISI, M. G, BIRRELL, M. A

“…House dust mite (HDM) is the major source of allergen in house dust and is strongly associated with the development of asthma. HDM can evoke a direct,…”
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Protein Release from Biodegradable Dextran Nanogels by Van Thienen, T. G, Raemdonck, K, Demeester, J, De Smedt, S. C

“…The use of drugs with intracellular targets will strongly depend on the availability of delivery systems that are able to deliver them to specific…”
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Protection of Oligonucleotides against Enzymatic Degradation by Pegylated and Nonpegylated Branched Polyethyleneimine by Remaut, K, Lucas, B, Raemdonck, K, Braeckmans, K, Demeester, J, De Smedt, S. C

“…Among the cationic polymers, polyethyleneimine (PEI) is a promising candidate for delivery of oligodeoxynucleotides (ODNs). In this study, we wondered whether…”
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Role of chemokines in diabetic retinopathy by Struyf, S., Mohammad, G., Imtiaz Nawaz, M., Van Raemdonck, K., De Hertogh, G., Van Damme, J., Abu El Asrar, A.

“…Summary We have detected altered expression of chemokines in the vitreous fluid of patients with proliferative diabetic retinopathy (PDR). In the early phase…”
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Interactions of siRNA loaded dextran nanogel with blood cells by Naeye, B., Raemdonck, K., Demeester, J., De Smedt, S.C.

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Matrix systems for siRNA delivery by Naeye, B, Raemdonck, K, Remaut, K, Demeester, J, De Smedt, S C

“…Over the last decade, considerable effort has been put in the implementation of RNA interference (RNAi) as a treatment for various disorders. As RNAi occurs in…”
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WS01.6 The rational design of nanomedicines for chronic pulmonary infection treatment: Does size really matter? by Forier, K, Messiaen, A.-S, Raemdonck, K, Nelis, H, De Smedt, S.C, Demeester, J, Coenye, T, Braeckmans, K

“…Objectives Several studies showed that encapsulating antibiotics in nanoparticles can improve the killing of biofilm bacteria. To ensure maximal delivery of…”
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Myofibroblasts in proliferative diabetic retinopathy can originate from infiltrating fibrocytes and through endothelial‐to‐mesenchymal transition (EndoMT) by Abu El Asrar, A., De Hertogh, G., van den Eynde, K., Alam, K., Van Raemdonck, K., Opdenakker, G., Van Damme, J., Geboes, K., Struyf, S.

“…Purpose The fibrovascular epiretinal membranes from patients with proliferative diabetic retinopathy (PDR) are characterized by the accumulation of a large…”
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Myofibroblasts in proliferative diabetic retinopathy can originate from infiltrating fibrocytes and through endothelial‐to‐mesenchymal transition (EndoMT) by Abu El Asrar, A., De Hertogh, G., van den Eynde, K., Alam, K., Van Raemdonck, K., Opdenakker, G., Van Damme, J., Geboes, K., Struyf, S.

“…Purpose The fibrovascular epiretinal membranes from patients with proliferative diabetic retinopathy (PDR) are characterized by the accumulation of a large…”
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Biodegradable dextran nanogels as functional carriers for the intracellular delivery of small interfering RNA by Raemdonck, K., Naeye, B., Høgset, A., Demeester, J., De Smedt, S.C.

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Can we better understand the intracellular behavior of DNA nanoparticles by fluorescence correlation spectroscopy? by Remaut, K., Lucas, B., Raemdonck, K., Braeckmans, K., Demeester, J., De Smedt, S.C.

“…The use of non-viral gene carriers to deliver small nucleic acids like antisense oligonucleotides (ODNs) and small interfering RNA (siRNA) remains an…”
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WS15.6 Development of nanomedicines for the treatment of pulmonary biofilm infections: Insights from advanced fluorescence microscopy studies by Forier, K, Messiaen, A.-S, Risseeuw, M, Van Calenbergh, S, Deschout, H, Raemdonck, K, Nelis, H, Danhier, F, Préat, V, De Baets, F, De Smedt, S, Demeester, J, Coenye, T, Braeckmans, K

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Risk analysis system for the transport of hazardous materials by Van Raemdonck, Koen, Macharis, Cathy, Mairesse, Olivier

“…In this paper, a literature study on risk analysis systems for the transport of hazardous materials was conducted. The insights that resulted from this…”
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PRE-FORMATION LOADING OF EXTRACELLULAR VESICLES WITH EXOGENOUS MOLECULES BY PHOTOPORATION by Ramon, J., Pinheiro, C., Vandendriessche, C., Lozano-Andrés, E., Arkesteijn, G.J., De Keersmaecker, H., Punj, D., Fraire, J., Geeurickx, E., Wauben, M.H., Vandenbroucke, R.E., Hendrix, A., Stremersch, S., De Smedt, S.C., Raemdonck, K., Braeckmans, K.

“…While initially thought that the function of extracellular vesicles (EVs) was merely waste disposal from cells, their crucial role in intercellular…”
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C98 HOT THINGS: INFLAMMATION, REMODELING, AND SYSTEMIC DISEASE IN PULMONARY HYPERTENSION: Himf/hmgb1 Signaling Axis Mediates Vascular Inflammation In The Pathogenesis Of Pulmonary Hypertension by Lin, Q, Fan, C, Yamaji-Kegan, K, Skinner, J T, Van Raemdonck, K, Fang, X, Johns, R A

“…Methods: The in vivo hypoxia-induced PH model with wild-type and HIMF-deficient mice, and the in vitro cell culture with the hRETN-treated THP-1 differentiated…”
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