Search Results - "Rae Bevan"

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    Clinical Pharmacokinetics of Ganciclovir in Patients with Normal and Impaired Renal Function by Sommadossi, Jean-Pierre, Rae Bevan, Teck Ling, Lee, Frank, Barbara Mastre, Melvin D. Chaplin, Clinton Nerenberg, Stuart Koretz, William C. Buhles, Jr

    Published in Reviews of infectious diseases (01-07-1988)
    “…The pharmacokinetics of ganciclovir was evaluated in 21 patients with life- or sight-threatening cytomegalovirus infections. Thirteen patients had normal renal…”
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    Journal Article
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    Catabolism of 3'-azido-3'-deoxythymidine in hepatocytes and liver microsomes, with evidence of formation of 3'-amino-3'-deoxythymidine, a highly toxic catabolite for human bone marrow cells by Cretton, E M, Xie, M Y, Bevan, R J, Goudgaon, N M, Schinazi, R F, Sommadossi, J P

    Published in Molecular pharmacology (01-02-1991)
    “…Metabolic studies in humans have demonstrated that 3'-azido-3'-deoxythymidine (AZT) is primarily eliminated as its 5'-O-glucuronide (GAZT). However, no…”
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    Journal Article