Search Results - "Rae, Giles A."

The antipyretic effect of dipyrone is unrelated to inhibition of PGE2 synthesis in the hypothalamus by Malvar, David do C, Soares, Denis M, Fabrício, Aline SC, Kanashiro, Alexandre, Machado, Renes R, Figueiredo, Maria J, Rae, Giles A, de Souza, Glória EP

“…BACKGROUND AND PURPOSE Bacterial lipopolysaccharide (LPS) induces fever through two parallel pathways; one, prostaglandin (PG)‐dependent and the other,…”
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Endothelins modulate inflammatory reaction in zymosan-induced arthritis: participation of LTB4, TNF-α, and CXCL-1 by Conte, Fernando de Paiva, Barja-Fidalgo, Christina, Verri, Jr, Waldiceu A, Cunha, Fernando Queiroz, Rae, Giles A, Penido, Carmen, Henriques, Maria das Graças M O

“…Endothelins (ETs) are involved in inflammatory events, including pain, fever, edema, and cell migration. ET‐1 levels are increased in plasma and synovial…”
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Mechanisms operated by endothelin ETA and ETB receptors in the trigeminal ganglion contribute to orofacial thermal hyperalgesia induced by infraorbital nerve constriction in rats by Chichorro, Juliana G, Zampronio, Aleksander R, Cabrini, Daniela A, Franco, Celia R.C, Rae, Giles A

“…Abstract Endothelins, acting through specific endothelin ETA and/or ETB receptors, participate in nociceptive processing in models of cancer, inflammatory and…”
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Endothelin-1 as a central mediator of LPS-induced fever in rats by Fabricio, Aline S.C., Rae, Giles A., D'Orléans-Juste, Pedro, Souza, Glória E.P.

“…Fever induced by E. coli lipopolysaccharide (LPS) in rats is substantially reduced by blockade of central endothelin ET B receptors. This study explores the…”
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Effects of endothelin ETA receptor antagonism on granulocyte and lymphocyte accumulation in LPS-induced inflammation by Sampaio, André L. F., Rae, Giles A., Henriques, Maria das Graças M. O.

“…Endothelin peptides play active roles in different aspects of inflammation. This study investigates the contribution of endogenous endothelins to…”
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Endothelin-1 (1-31) is an intermediate in the production of endothelin-1 after big endothelin-1 administration in vivo by FECTEAU, Marie-Hélène, HONORE, Jean-Claude, PLANTE, Mirco, LABONTE, Julie, RAE, Giles A, D'ORLEANS-JUSTE, Pedro

“…The precursor of endothelin-1, big endothelin-1, can be hydrolyzed by chymase to generate endothelin-1 (1-31) in vitro. In the present study, we explored the…”
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Cell viability and cytotoxicity of inkjet-printed flexible organic electrodes on parylene C by Mandelli, Jaqueline S., Koepp, Janice, Hama, Adel, Sanaur, Sébastien, Rae, Giles A., Rambo, Carlos R.

“…This study reports on the fabrication of biocompatible organic devices by means of inkjet printing with a novel combination of materials. The devices were…”
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Peripheral substance P and neurokinin-1 receptors have a role in inflammatory and neuropathic orofacial pain models by Teodoro, Fernanda C, Tronco Júnior, Marcos F, Zampronio, Aleksander R, Martini, Alessandra C, Rae, Giles A, Chichorro, Juliana G

“…Abstract There is accumulating evidence that substance P released from peripheral sensory neurons participates in inflammatory and neuropathic pain. In this…”
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Endocannabinoids, through opioids and prostaglandins, contribute to fever induced by key pyrogenic mediators by Fraga, Daniel, Zanoni, Cristiane I.S, Zampronio, Aleksander R, Parada, Carlos A, Rae, Giles A, Souza, Glória E.P

“…Highlights • Endocannabinoids participate in the fever induced by TNF, IL-1β, IL-6, CRF and ET-1. • Endocannabinoids are not involved in the fever induced by…”
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The antipyretic effect of dipyrone is unrelated to inhibition of PGE 2 synthesis in the hypothalamus by Malvar, David do C, Soares, Denis M, Fabrício, Aline SC, Kanashiro, Alexandre, Machado, Renes R, Figueiredo, Maria J, Rae, Giles A, de Souza, Glória EP

“…BACKGROUND AND PURPOSE Bacterial lipopolysaccharide (LPS) induces fever through two parallel pathways; one, prostaglandin (PG)‐dependent and the other,…”
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Contribution of peripheral endothelin ETA and ETB receptors in neuropathic pain induced by spinal nerve ligation in rats by Werner, Maria Fernanda P, Trevisani, Marcello, Campi, Barbara, André, Eunice, Geppetti, Pierangelo, Rae, Giles A

“…Abstract Endothelins (ETs) contribute to the sensory changes seen in animals models of inflammatory, cancer and diabetic neuropathic pain, but little is known…”
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Roles of endothelin ETA and ETB receptors in nociception and chemical, thermal and mechanical hyperalgesia induced by endothelin-1 in the rat hindpaw by MOTTA, Emerson M, CHICHORRO, Juliana G, D'ORLEANS-JUSTE, Pedro, RAE, Giles A

“…Evidence on the relative roles of endothelin ET(A) and ET(B) receptors in mediating the nociceptive and hyperalgesic actions of endothelin-1 is still…”
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Effects of endothelin-1 on capsaicin-induced nociception in mice by Piovezan, Anna P, D'Orléans-Juste, Pedro, Tonussi, Carlos R, Rae, Giles A

“…The influence of endothelin-1 on nociception induced by capsaicin was assessed in the mouse hindpaw. Local endothelin-1 injection (1 to 20 pmol/paw) 30 min…”
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Cardiovascular responses to sciatic nerve stimulation are blocked by paratrigeminal nucleus lesion by Yu, Yun-Guo, Caous, Cristofer A, Balan, Antonio C, Rae, Giles A, Lindsey, Charles J

“…The paratrigeminal nucleus (Pa5) receives primary sensory inputs from the vagus, glossopharyngeal, and trigeminal nerves and has efferent projections to the…”
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Involvement of PGE2 and RANTES in Staphylococcus aureus-induced fever in rats by Martins, Juliano M, Longhi-Balbinot, Daniela T, Soares, Denis M, Figueiredo, Maria José, Malvar, David do C, de Melo, Miriam C C, Rae, Giles A, Souza, Glória E P

“…This study investigated the involvement of prostaglandins and regulated on activation, normal T cell expressed and secreted (RANTES), in fever induced by live…”
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GABAA signalling is involved in N/OFQ anxiolytic-like effects but not in nocistatin anxiogenic-like action as evaluated in the mouse elevated plus maze by GAUIOLI, Elaine C, DUARTE, Filipe S, GUERRINI, Remo, CALA, Girolamo, RAE, Giles A, DE LIMA, Thereza C. M

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GABA A signalling is involved in N/OFQ anxiolytic-like effects but not in nocistatin anxiogenic-like action as evaluated in the mouse elevated plus maze by Gavioli, Elaine C., Duarte, Filipe S., Guerrini, Remo, Calo, Girolamo, Rae, Giles A., M. De Lima, Thereza C.

“…Nociceptin/orphanin FQ (N/OFQ) and nocistatin are two neuropeptides originated from the same precursor prepronociceptin/orphanin FQ (ppN/OFQ). N/OFQ is the…”
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Central injections of nocistatin or its C‐terminal hexapeptide exert anxiogenic‐like effect on behaviour of mice in the plus‐maze test by Gavioli, Elaine C, Rae, Giles A, Calo', Girolamo, Guerrini, Remo, De Lima, Thereza C M

“…Nocistatin (NST) antagonizes several actions of nociceptin/orphanin FQ (N/OFQ), but acts on distinct receptors. As N/OFQ exerts anxiolytic‐like actions in…”
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Endothelin‐1‐induced ETA receptor‐mediated nociception, hyperalgesia and oedema in the mouse hind‐paw: modulation by simultaneous ETB receptor activation by Piovezan, Anna P, D'Orléans‐Juste, Pedro, Souza, Glória E P, Rae, Giles A

“…Endothelin‐1 causes ETA receptor‐mediated enhancement of capsaicin‐induced nociception in mice. We have assessed if this hyperalgesic effect of endothelin‐1 is…”
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Endothelins contribute towards nociception induced by antigen in ovalbumin‐sensitised mice by Piovezan, Anna P, D'Orléans‐Juste, Pedro, Frighetto, Monica, Souza, Glória E P, Henriques, Maria G M O, Rae, Giles A

“…The contribution of endogenous endothelins to nociceptive responses elicited by ovalbumin (OVA) in the hind‐paw of mice sensitised to this antigen (50 μg OVA+5…”
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