Search Results - "Rady, Islam"
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Urolithin A induces cell cycle arrest and apoptosis by inhibiting Bcl-2, increasing p53-p21 proteins and reactive oxygen species production in colorectal cancer cells
Published in Cell stress & chaperones (01-05-2021)“…Colorectal cancer (CRC) is the second most common gastrointestinal cancer globally. Prevention of tumor cell proliferation and metastasis is vital for…”
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Graviola (Annona muricata) Exerts Anti-Proliferative, Anti-Clonogenic and Pro-Apoptotic Effects in Human Non-Melanoma Skin Cancer UW-BCC1 and A431 Cells In Vitro: Involvement of Hedgehog Signaling
Published in International journal of molecular sciences (16-06-2018)“…Non-melanoma skin cancers (NMSCs) are the leading cause of skin cancer-related morbidity and mortality. Effective strategies are needed to control NMSC…”
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Two Red Sea Sponge Extracts (Negombata magnifica and Callyspongia siphonella) Induced Anticancer and Antimicrobial Activity
Published in Applied sciences (01-02-2022)“…Bioactive compounds extracted from marine organisms showed several biological activities. The present study is an extension of our earlier studies where we…”
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DFT Calculations, Pro-Apoptotic Effects, and Anti-Infective Investigations of Alkaloids Isolated from the Stem Bark Extract of Enantia chlorantha
Published in Drugs and drug candidates (07-03-2024)“…Fractionation of the stem bark of Enantia chlorantha Oliv yields three alkaloids, palmatine (1), jatrorrhizine (2), columbamine (3), and β-Sitosterol (4). In…”
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Bioactive Dietary VDR Ligands Regulate Genes Encoding Biomarkers of Skin Repair That Are Associated with Risk for Psoriasis
Published in Nutrients (04-02-2018)“…Treatment with 1,25-dihydroxyvitamin D₃ (1,25D) improves psoriasis symptoms, possibly by inducing the expression of late cornified envelope ( )3 genes involved…”
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Melittin, a major peptide component of bee venom, and its conjugates in cancer therapy
Published in Cancer letters (28-08-2017)“…Abstract Melittin (MEL), a major peptide component of bee venom, is an attractive candidate for cancer therapy. This agent has shown a variety of anti-cancer…”
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Abstract 3725: Pre-clinical evaluation of prostate specific membrane antigen (PSMA) nanobioconjugate encapsulating green tea polyphenol EGCG for prostate cancer
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract For prostate cancer green tea constituent (-)-epigallocatechin-3-gallate (EGCG) has shown promise in preclinical, geographical and epidemiological…”
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Targeted nanoparticles encapsulating (−)-epigallocatechin-3-gallate for prostate cancer prevention and therapy
Published in Scientific reports (01-02-2017)“…Earlier we introduced the concept of ‘ nanochemoprevention ’ i.e. the use of nanotechnology to improve the outcome of cancer chemoprevention. Here, we extended…”
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Abstract 4502: Aptamer conjugated prostate specific membrane antigen (PSMA) targeting nanobees for prostate cancer prevention and therapy
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Melittin (MEL), a major peptide component of bee venom (BV), has shown chemopreventive as well as chemotherapeutic effects against many cancers in…”
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Urolithin A affects cellular migration and modulates matrix metalloproteinase expression in colorectal cancer cells
Published in Cell biochemistry and function (01-04-2024)“…Colorectal cancer (CRC) is the world's second most common gastrointestinal malignancy. Preventing tumor cell proliferation and dissemination is critical for…”
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Abstract 5808: Hedgehog pathway inhibitors itraconazole and cyclopamine produce synergistic suppression of Pten deficient prostate cancer
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Hedgehog (Hh) signaling plays an important role in prostate development and is also a characteristic feature of prostate cancer (PCa). The ability of…”
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Anticancer Properties of Graviola (Annona muricata): A Comprehensive Mechanistic Review
Published in Oxidative medicine and cellular longevity (01-01-2018)“…Graviola (Annona muricata) is a small deciduous tropical evergreen fruit tree, belonging to the Annonaceae family, and is widely grown and distributed in…”
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Antiproliferative Activity, Proapoptotic Effect, and Cell Cycle Arrest in Human Cancer Cells of Some Marine Natural Product Extract
Published in Oxidative medicine and cellular longevity (2020)“…Bioactive constituents of numerous marine organisms have been investigated recently for their preclinical and clinical anticancer activity. Three marine…”
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