Search Results - "Radulescu, Camelia"

PD-L1 testing in urothelial bladder cancer: essentials of clinical practice by Rouanne, Mathieu, Radulescu, Camélia, Adam, Julien, Allory, Yves

“…Purpose While immunotherapy has become an increasingly attractive strategy in patients with urothelial bladder cancer, the need for a biomarker to identify…”
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Tim-3 Expression on Tumor-Infiltrating PD-1 + CD8 + T Cells Correlates with Poor Clinical Outcome in Renal Cell Carcinoma by Granier, Clémence, Dariane, Charles, Combe, Pierre, Verkarre, Virginie, Urien, Saïk, Badoual, Cécile, Roussel, Hélène, Mandavit, Marion, Ravel, Patrice, Sibony, Mathilde, Biard, Lucie, Radulescu, Camélia, Vinatier, Emeline, Benhamouda, Nadine, Peyromaure, Michael, Oudard, Stéphane, Méjean, Arnaud, Timsit, Marc-Olivier, Gey, Alain, Tartour, Eric

“…Inhibitory receptors expressed by T cells mediate tolerance to tumor antigens, with coexpression of these receptors exacerbating this dysfunctional state…”
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BCG therapy downregulates HLA-I on malignant cells to subvert antitumor immune responses in bladder cancer by Rouanne, Mathieu, Adam, Julien, Radulescu, Camélia, Letourneur, Diane, Bredel, Delphine, Mouraud, Séverine, Goubet, Anne-Gaëlle, Leduc, Marion, Chen, Noah, Tan, Tuan Zea, Signolle, Nicolas, Bigorgne, Amélie, Dussiot, Michael, Tselikas, Lambros, Susini, Sandrine, Danlos, François-Xavier, Schneider, Anna K, Chabanon, Roman, Vacher, Sophie, Bièche, Ivan, Lebret, Thierry, Allory, Yves, Soria, Jean-Charles, Arpaia, Nicholas, Kroemer, Guido, Kepp, Oliver, Thiery, Jean Paul, Zitvogel, Laurence, Marabelle, Aurélien

“…Patients with high-risk, nonmuscle-invasive bladder cancer (NMIBC) frequently relapse after standard intravesical bacillus Calmette-Guérin (BCG) therapy and…”
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Stromal lymphocyte infiltration is associated with tumour invasion depth but is not prognostic in high-grade T1 bladder cancer by Rouanne, Mathieu, Betari, Reem, Radulescu, Camélia, Goubar, Aïcha, Signolle, Nicolas, Neuzillet, Yann, Allory, Yves, Marabelle, Aurélien, Adam, Julien, Lebret, Thierry

“…Assessment of tumour-infiltrating lymphocytes (TILs) can provide important prognostic information in various cancers and may be of value in predicting response…”
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A 16-gene assay to predict recurrence after surgery in localised renal cell carcinoma: development and validation studies by Rini, Brian, Prof, Goddard, Audrey, PhD, Knezevic, Dejan, PhD, Maddala, Tara, PhD, Zhou, Ming, MD, Aydin, Hakan, MD, Campbell, Steven, MD, Elson, Paul, PhD, Koscielny, Serge, PhD, Lopatin, Margarita, MS, Svedman, Christer, MD, Martini, Jean-Francois, PhD, Williams, J Andrew, PhD, Verkarre, Virginie, MD, Radulescu, Camelia, MD, Neuzillet, Yann, MD, Hemmerlé, Isabelle, BS, Timsit, Marc Olivier, MD, Tsiatis, Athanasios C, MD, Bonham, Michael, MD, Lebret, Thierry, Prof, Mejean, Arnaud, Prof, Escudier, Bernard, MD

“…Summary Background The likelihood of tumour recurrence after nephrectomy in localised clear cell renal cell carcinoma is well characterised by clinical and…”
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c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression by Sim, Wen Jing, Iyengar, Prasanna Vasudevan, Lama, Dilraj, Lui, Sarah Kit Leng, Ng, Hsien Chun, Haviv-Shapira, Lior, Domany, Eytan, Kappei, Dennis, Tan, Tuan Zea, Saei, Azad, Jaynes, Patrick William, Verma, Chandra Shekhar, Kumar, Alan Prem, Rouanne, Mathieu, Ha, Hong Koo, Radulescu, Camelia, ten Dijke, Peter, Eichhorn, Pieter Johan Adam, Thiery, Jean Paul

“…Treatment of muscle-invasive bladder cancer remains a major clinical challenge. Aberrant HGF/c-MET upregulation and activation is frequently observed in…”
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Plasmacytoid urothelial carcinoma (UC) are luminal tumors with similar CD8+ Tcell density and PD-L1 protein expression on immune cells as compared to conventional UC by Kossaï, Myriam, Radulescu, Camélia, Adam, Julien, Dziegielewski, Anaïs, Signolle, Nicolas, Sibony, Mathilde, Lebret, Thierry, Allory, Yves, Rouanne, Mathieu

“…•Plasmacytoid urothelial carcinomas (UC) represent a rare and aggressive variant with poor outcome and a low sensitivity to chemotherapy.•Phenotypically,…”
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From arterial stiffness to kidney graft microvasculature: Mortality and graft survival within a cohort of 220 kidney transplant recipients by Cheddani, Lynda, Radulescu, Camélia, Chaignon, Michel, Karras, Alexandre, Neuzillet, Yann, Duong, Jean-Paul, Tabibzadeh, Nahid, Letavernier, Emmanuel, Delahousse, Michel, Haymann, Jean-Philippe

“…Aortic stiffness assessed by carotid-femoral pulse wave velocity (CF-PWV) is a predictor of mortality in several populations. However, little is known in…”
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Prostate Cancer Antigen 3 Score Accurately Predicts Tumour Volume and Might Help in Selecting Prostate Cancer Patients for Active Surveillance by Ploussard, Guillaume, Durand, Xavier, Xylinas, Evanguelos, Moutereau, Stéphane, Radulescu, Camélia, Forgue, Aurélien, Nicolaiew, Nathalie, Terry, Stéphane, Allory, Yves, Loric, Sylvain, Salomon, Laurent, Vacherot, Francis, de la Taille, Alexandre

“…Abstract Background The optimal selection of prostate cancer (PCa) patients for active surveillance (AS) is currently being debated. Objective To assess the…”
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Immune checkpoints are predominantly co-expressed by clonally expanded CD4 + FoxP3 + intratumoral T-cells in primary human cancers by Bredel, Delphine, Tihic, Edi, Mouraud, Séverine, Danlos, François-Xavier, Susini, Sandrine, Aglave, Marine, Alfaro, Alexia, Mohamed-Djalim, Chifaou, Rouanne, Mathieu, Halse, Héloise, Bigorgne, Amélie, Tselikas, Lambros, Dalle, Stéphane, Hartl, Dana M, Baudin, Eric, Guettier, Catherine, Vibert, Eric, Rosmorduc, Olivier, Robert, Caroline, Ferlicot, Sophie, Parier, Bastien, Albiges, Laurence, de Montpreville, Vincent Thomas, Besse, Benjamin, Mercier, Olaf, Even, Caroline, Breuskin, Ingrid, Classe, Marion, Radulescu, Camélia, Lebret, Thierry, Pautier, Patricia, Gouy, Sébastien, Scoazec, Jean-Yves, Zitvogel, Laurence, Marabelle, Aurélien, Bonvalet, Mélodie

“…In addition to anti-PD(L)1, anti-CTLA-4 and anti-LAG-3, novel immune checkpoint proteins (ICP)-targeted antibodies have recently failed to demonstrate…”
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Multiple recurrences and risk of disease progression in patients with primary low-grade (TaG1) non-muscle-invasive bladder cancer and with low and intermediate EORTC-risk score by Simon, Marie, Bosset, Pierre-Olivier, Rouanne, Mathieu, Benhamou, Simone, Radulescu, Camelia, Molinié, Vincent, Neuzillet, Yann, Paoletti, Xavier, Lebret, Thierry

“…To assess the prognostic value of multiple recurrences on the risk of progression in a large cohort of TaG1 bladder cancer of low and intermediate risk based…”
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Artificial intelligence to improve cytology performance in urothelial carcinoma diagnosis: results from validation phase of the French, multicenter, prospective VISIOCYT1 trial by Lebret, Thierry, Paoletti, Xavier, Pignot, Geraldine, Roumiguié, Mathieu, Colombel, Marc, Savareux, Laurent, Verhoest, Grégory, Guy, Laurent, Rigaud, Jérome, De Vergie, Stéphane, Poinas, Grégoire, Droupy, Stéphane, Kleinclauss, François, Courtade-Saïdi, Monique, Piaton, Eric, Radulescu, Camelia, Rioux-Leclercq, Nathalie, Kandel-Aznar, Christine, Renaudin, Karine, Cochand-Priollet, Béatrix, Allory, Yves, Nivet, Sébastien, Rouprêt, Morgan

“…Purpose Cytology and cystoscopy, the current gold standard for diagnosing urothelial carcinomas, have limits: cytology has high interobserver variability with…”
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A comparative study of peptide-based imaging agents [68Ga]Ga-PSMA-11, [68Ga]Ga-AMBA, [68Ga]Ga-NODAGA-RGD and [68Ga]Ga-DOTA-NT-20.3 in preclinical prostate tumour models by Zhang-Yin, Jules, Provost, Claire, Cancel-Tassin, Géraldine, Rusu, Timofei, Penent, Mallaurie, Radulescu, Camelia, Comperat, Eva, Cussenot, Olivier, Montravers, Françoise, Renard-Penna, Raphaële, Talbot, Jean-Noël, Prignon, Aurélie

“…Peptide-based imaging agents targeting prostate-specific membrane antigen (PSMA) have revolutionized the evaluation of biochemical recurrence of prostate…”
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Sexual steroids in serum and prostatic tissue of human non‐cancerous prostate (STERPROSER trial) by Neuzillet, Yann, Raynaud, Jean‐Pierre, Radulescu, Camélia, Fiet, Jean, Giton, Franck, Dreyfus, Jean‐François, Ghoneim, Tarek P., Lebret, Thierry, Botto, Henry

“…Background The specific involvement of the sex steroids in the growth of the prostatic tissue remains unclear. Sex steroid concentrations in plasma and in…”
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The value of urinary prostate cancer gene 3 (PCA3) scores in predicting pathological features at radical prostatectomy by Durand, Xavier, Xylinas, Evanguelos, Radulescu, Camelia, Haus‐Cheymol, Rachel, Moutereau, Stephane, Ploussard, Gillaume, Forgues, Aurelien, Robert, Grégoire, Vacherot, Francis, Loric, Sylvain, Allory, Yves, Ruffion, Alain, de la Taille, Alexandre

“…Study Type – Diagnostic (exploratory cohort) Level of Evidence 2b What's known on the subject? and What does the study add? PCA3 scores correlate to numerous…”
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Aggressiveness of Localized Prostate Cancer: the Key Value of Testosterone Deficiency Evaluated by Both Total and Bioavailable Testosterone: AndroCan Study Results by Neuzillet, Yann, Raynaud, Jean-Pierre, Dreyfus, Jean-François, Radulescu, Camélia, Rouanne, Mathieu, Schneider, Marc, Krish, Sylvie, Rouprêt, Morgan, Drouin, Sarah J., Comperat, Eva, Galiano, Marc, Cathelineau, Xavier, Validire, Pierre, Molinié, Vincent, Fiet, Jean, Giton, Franck, Lebret, Thierry, Botto, Henry

“…Failure rates after first-line treatment of localized prostate cancer (PCa) treatment remain high. Improvements to patient selection and identification of…”
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Author Correction: c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression by Sim, Wen Jing, Iyengar, Prasanna Vasudevan, Lama, Dilraj, Lui, Sarah Kit Leng, Ng, Hsien Chun, Haviv-Shapira, Lior, Domany, Eytan, Kappei, Dennis, Tan, Tuan Zea, Saei, Azad, Jaynes, Patrick William, Verma, Chandra Shekhar, Kumar, Alan Prem, Rouanne, Mathieu, Ha, Hong Koo, Radulescu, Camelia, ten Dijke, Peter, Eichhorn, Pieter Johan Adam, Thiery, Jean Paul

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Neuroendocrine Carcinoma of the Urinary Bladder: A Large, Retrospective Study From the French Genito-Urinary Tumor Group by Sroussi, Marine, Elaidi, Reza, Fléchon, Aude, Lorcet, Marianne, Borchiellini, Delphine, Tardy, Magalie P., Gravis, Gwenaelle, Guérin, Mathilde, Laguerre, Brigitte, Estrade, Florian, Delva, Rémi, Barthélémy, Phillipe, Loriot, Yohann, Lavaud, Pernelle, Lebret, Thierry, Neuzillet, Yann, Penel, Nicolas, Houede, Nadine, Pouessel, Damien, Rousseau, Benoit, Mussat, Elodie, Gross-Goupil, Marine, Culine, Stéphane, Gauthier, Hélène, Gobert, Aurélien, Roupret, Morgan, Huillard, Olivier, Tartas, Sophie, Radulescu, Camélia, Allory, Yves, Oudard, Stéphane

“…Neuroendocrine carcinoma of the urinary bladder (NCUB) is rare, accounting for < 1% of bladder cancer cases, with scarce reported data available. We…”
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Positive surgical margins after radical prostatectomy: What should we care about? by Pettenati, Caroline, Neuzillet, Yann, Radulescu, Camelia, Hervé, Jean-Marie, Molinié, Vincent, Lebret, Thierry

“…Purpose Positive surgical margins (PSMs) after radical prostatectomy (RP) are a known factor associated with biochemical recurrence (BCR) and raise the issue…”
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Assessment of diagnostic gain with hexaminolevulinate (HAL) in the setting of newly diagnosed non–muscle-invasive bladder cancer with positive results on urine cytology by Neuzillet, Yann, M.D., Ph.D, Methorst, Charlotte, M.D, Schneider, Marc, M.D, Lebret, Thierry, M.D., Ph.D, Rouanne, Mathieu, M.D, Radulescu, Camelia, M.D, Molinie, Vincent, M.D., Ph.D, Dreyfus, Jean-François, M.D., Ph.D, Pelcat, Veronique, Botto, Henry, M.D

“…Abstract Objective In accordance with the European Association of Urology guidelines, a second transurethral resection of the bladder (TURB) is recommended for…”
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