Search Results - "Radtke, Jared"

Autoantibodies directed against glutamate decarboxylase interfere with glucose‐stimulated insulin secretion in dispersed rat islets by Kamat, Varun, Radtke, Jared R., Hu, Qingxun, Wang, Wang, Sweet, Ian R., Hampe, Christiane S.

“…Islet autoantibodies, including autoantibodies directed against the 65kDa isoform of glutamate decarboxylase (GAD65Ab), are present in the majority of patients…”
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Monoclonal antibodies to 65kDa glutamate decarboxylase induce epitope specific effects on motor and cognitive functions in rats by Hampe, Christiane S, Petrosini, Laura, De Bartolo, Paola, Caporali, Paola, Cutuli, Debora, Laricchiuta, Daniela, Foti, Francesca, Radtke, Jared R, Vidova, Veronika, Honnorat, Jérôme, Manto, Mario

“…Stiff Person Syndrome (SPS) is a rare autoimmune movement disorder characterized by the presence of autoantibodies specific to the smaller isoform of glutamate…”
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GAD65 autoantibody characteristics in patients with co-occurring type 1 diabetes and epilepsy may help identify underlying epilepsy etiologies by Liimatainen, Suvi, Honnorat, Jerome, Pittock, Sean J, McKeon, Andrew, Manto, Mario, Radtke, Jared R, Hampe, Christiane S

“…Autoantibodies against the smaller isoform of glutamate decarboxylase (GAD65Ab) reflect autoimmune etiologies in Type 1 diabetes (T1D) and several neurological…”
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Effect of dietary palmitic and stearic acids on sucrose motivation and hypothalamic and striatal cell signals in the rat by Figlewicz, Dianne P, Jay, Jennifer, West, Constance H, Zavosh, Aryana, Hampe, Christiane S, Radtke, Jared R, Raskind, Murray A, Peskind, Elaine R

“…We have reported that motivation for sucrose is increased in rats fed a moderate (31%) mixed-fat diet for 4-6 wk. In this study, rats were fed diets containing…”
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Decline in titers of anti-idiotypic antibodies specific to autoantibodies to GAD65 (GAD65Ab) precedes development of GAD65Ab and type 1 diabetes by Larsson, Helena Elding, Jönsson, Ida, Lernmark, Ake, Ivarsson, Sten, Radtke, Jared R, Hampe, Christiane S

“…The humoral Idiotypic Network consisting of antibodies and their anti-idiotypic antibodies (anti-Id) can be temporarily upset by antigen exposure. In the…”
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A method for high-throughput functional imaging of single cells within heterogeneous cell preparations by Neal, Adam S., Rountree, Austin M., Radtke, Jared R., Yin, Jianzhu, Schwartz, Michael W., Hampe, Christiane S., Posner, Jonathan D., Cirulli, Vincenzo, Sweet, Ian R.

“…Functional characterization of individual cells within heterogeneous tissue preparations is challenging. Here, we report the development of a versatile imaging…”
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Anti-idiotypic antibody specific to GAD65 autoantibody prevents type 1 diabetes in the NOD mouse by Wang, Xin, Zhang, Aixia, Liu, Yu, Chen, Shi, Feng, Zhenqing, Shang, Wenbin, Maziarz, Marlena, Radtke, Jared, Hampe, Christiane S

“…Overt autoantibodies to the smaller isoform of glutamate decarboxylase (GAD65Ab) are a characteristic in patients with Type 1 diabetes (T1D). Anti-idiotypic…”
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High titers of autoantibodies to glutamate decarboxylase in type 1 diabetes patients: epitope analysis and inhibition of enzyme activity by Hampe, Christiane S, Maitland, Murray E, Gilliam, Lisa K, Phan, Thanh-H Thi, Sweet, Ian R, Radtke, Jared R, Bota, Vasile, Ransom, Bruce R, Hirsch, Irl B

“…Autoantibodies to glutamate decarboxylase (GAD65Ab) are found in patients with autoimmune neurological disorders or type 1 diabetes. The correct diagnosis of…”
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Laser microdissection and capture of pure cardiomyocytes and fibroblasts from infarcted heart regions: perceived hyperoxia induces p21 in peri-infarct myocytes by Kuhn, Donald E, Roy, Sashwati, Radtke, Jared, Khanna, Savita, Sen, Chandan K

“…Myocardial infarction caused by ischemia-reperfusion in the coronary vasculature is a focal event characterized by an infarct-core, bordering peri-infarct zone…”
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Data-Driven Phenotyping of Presymptomatic Type 1 Diabetes Using Longitudinal Autoantibody Profiles by Ghalwash, Mohamed, Anand, Vibha, Ng, Kenney, Dunne, Jessica L, Lou, Olivia, Lundgren, Markus, Hagopian, William A, Rewers, Marian, Ziegler, Anette-G, Veijola, Riitta

“…To characterize distinct islet autoantibody profiles preceding stage 3 type 1 diabetes. The T1DI (Type 1 Diabetes Intelligence) study combined data from 1,845…”
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Refining the Definition of Stage 1 Type 1 Diabetes: An Ontology-Driven Analysis of the Heterogeneity of Multiple Islet Autoimmunity by Frohnert, Brigitte I, Ghalwash, Mohamed, Li, Ying, Ng, Kenney, Dunne, Jessica L, Lundgren, Markus, Hagopian, William, Lou, Olivia, Winkler, Christiane, Toppari, Jorma, Veijola, Riitta, Anand, Vibha

“…To estimate the risk of progression to stage 3 type 1 diabetes based on varying definitions of multiple islet autoantibody positivity (mIA). Type 1 Diabetes…”
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Prevalence and Regional Distribution of Autoantibodies Against GAD65Ab in a European Population Without Diabetes: The EPIC-InterAct Study by Rolandsson, Olov, Hampe, Christiane S, Wennberg, Patrik, Radtke, Jared, Langenberg, Claudia, Wareham, Nicholas

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Control of Insulin Secretion by Cytochrome c and Calcium Signaling in Islets with Impaired Metabolism by Rountree, Austin M., Neal, Adam S., Lisowski, Mark, Rizzo, Norma, Radtke, Jared, White, Sarah, Luciani, Dan S., Kim, Francis, Hampe, Christiane S., Sweet, Ian R.

“…The aim of the study was to assess the relative control of insulin secretion rate (ISR) by calcium influx and signaling from cytochrome c in islets where, as…”
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Masked and Overt Autoantibodies Specific to the DPD Epitope of 65-kDa Glutamate Decarboxylase (GAD65-DPD) Are Associated With Preserved β-Cell Functional Reserve in Ketosis-Prone Diabetes by Oak, Shilpa, Gaur, Lakshmi K, Radtke, Jared, Patel, Roshni, Iyer, Dinakar, Ram, Nalini, Gaba, Ruchi, Balasubramanyam, Ashok, Hampe, Christiane S

“…Context: Ketosis-prone diabetes (KPD), defined by presentation with diabetic ketoacidosis (DKA), comprises 4 subgroups based on the presence or absence of…”
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Decline in Titers of Anti-Idiotypic Antibodies Specific to Autoantibodies to GAD65 by Larsson, Helena Elding, Jönsson, Ida, Lernmark, Åke, Ivarsson, Sten, Radtke, Jared R, Hampe, Christiane S

“…The humoral Idiotypic Network consisting of antibodies and their anti-idiotypic antibodies (anti-Id) can be temporarily upset by antigen exposure. In the…”
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Characterization of the structural and functional changes in the myocardium following focal ischemia-reperfusion injury by Ojha, Navdeep, Roy, Sashwati, Radtke, Jared, Simonetti, Orlando, Gnyawali, Surya, Zweier, Jay L, Kuppusamy, Periannan, Sen, Chandan K

“…High-resolution (11.7 T) cardiac magnetic resonance imaging (MRI) and histological approaches have been employed in tandem to characterize the secondary damage…”
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ZnT8 autoantibody titers in type 1 diabetes patients decline rapidly after clinical onset by Vaziri-Sani, Fariba, Oak, Shilpa, Radtke, Jared, Lernmark, ke, Lynch, Kristian, Agardh, Carl.-D., Cilio, Corrado M., Lethagen, sa L., Örtqvist, Eva, Landin-Olsson, Mona, Törn, Carina, Hampe, Christiane S.

“…Autoantibodies to the islet-specific zinc transporter isoform 8 (ZnT8) are detected in the majority of type 1 diabetes patients prior to and at clinical…”
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Laser microdissection and pressure-catapulting technique to study gene expression in the reoxygenated myocardium by Kuhn, Donald E, Roy, Sashwati, Radtke, Jared, Gupta, Sudip, Sen, Chandan K

“…For focal events such as myocardial infarction, it is important to dissect infarction-induced biological responses as a function of space with respect to the…”
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Comparison of three assays for the detection of GAD65Ab-specific anti-idiotypic antibodies by Oak, Shilpa, Radtke, Jared, Landin-Olsson, Mona, Törn, Carina, Lernmark, Ake, Hampe, Christiane S.

“…Anti-idiotypic antibodies (anti-Id) to autoantibodies are present in several autoimmune diseases and are hypothesized to have regulatory function. Recently we…”
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Decline in Titers of Anti-Idiotypic Antibodies Specific to Autoantibodies to GAD65 (GAD65Ab) Precedes Development of GAD65Ab and Type 1 Diabetes. e65173 by Larsson, Helena Elding, Jonsson, Ida, Lernmark, Aake, Ivarsson, Sten, Radtke, Jared R, Hampe, Christiane S

“…The humoral Idiotypic Network consisting of antibodies and their anti-idiotypic antibodies (anti-Id) can be temporarily upset by antigen exposure. In the…”
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