Search Results - "Radovica‐Spalvina, Ilze"

Lack of significant differences between gastrointestinal tract microbial population structure of Helicobacter pylori‐infected subjects before and 2 years after a single eradication event by Gudra, Dita, Pupola, Darta, Skenders, Girts, Leja, Marcis, Radovica‐Spalvina, Ilze, Gorskis, Henrihs, Vangravs, Reinis, Fridmanis, Davids

“…Background According to recent estimates 80% of Latvian population is infected with Helicobacter pylori thus their susceptibility to numerous gastric tract…”
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Comprehensive characterization of RNA cargo of extracellular vesicles in breast cancer patients undergoing neoadjuvant chemotherapy by Sadovska, Lilite, Zayakin, Pawel, Eglītis, Kristaps, Endzeliņš, Edgars, Radoviča-Spalviņa, Ilze, Avotiņa, Elīza, Auders, Jānis, Keiša, Laura, Liepniece-Karele, Inta, Leja, Mārcis, Eglītis, Jānis, Linē, Aija

“…Extracellular vesicles (EVs) are g7aining increased attention as carriers of cancer-derived molecules for liquid biopsies. Here, we studied the dynamics of EV…”
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Plasma and urinary extracellular vesicles as a source of RNA biomarkers for prostate cancer in liquid biopsies by Bajo-Santos, Cristina, Brokāne, Agnese, Zayakin, Pawel, Endzeliņš, Edgars, Soboļevska, Kristīne, Belovs, Alberts, Jansons, Juris, Sperga, Māris, Llorente, Alicia, Radoviča-Spalviņa, Ilze, Lietuvietis, Vilnis, Linē, Aija

“…Extracellular vesicles (EVs) have emerged as a very attractive source of cancer- derived RNA biomarkers for the early detection, prognosis and monitoring of…”
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Association of metformin administration with gut microbiome dysbiosis in healthy volunteers by Elbere, Ilze, Kalnina, Ineta, Silamikelis, Ivars, Konrade, Ilze, Zaharenko, Linda, Sekace, Kristine, Radovica-Spalvina, Ilze, Fridmanis, Davids, Gudra, Dita, Pirags, Valdis, Klovins, Janis

“…Metformin is a widely used first-line drug for treatment of type 2 diabetes. Despite its advantages, metformin has variable therapeutic effects,…”
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Ryegrass mottle virus complete genome determination and development of infectious cDNA by combining two methods- 3' RACE and RNA-Seq by Balke, Ina, Silamikelis, Ivars, Radovica-Spalvina, Ilze, Zeltina, Vilija, Resevica, Gunta, Fridmanis, Davids, Zeltins, Andris

“…Ryegrass mottle virus (RGMoV; genus: Sobemovirus) is a single-stranded positive RNA virus with a 30 nm viral particle size. It exhibits T = 3 symmetry with 180…”
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Metformin strongly affects transcriptome of peripheral blood cells in healthy individuals by Ustinova, Monta, Silamikelis, Ivars, Kalnina, Ineta, Ansone, Laura, Rovite, Vita, Elbere, Ilze, Radovica-Spalvina, Ilze, Fridmanis, Davids, Aladyeva, Jekaterina, Konrade, Ilze, Pirags, Valdis, Klovins, Janis

“…Metformin is a commonly used antihyperglycaemic agent for the treatment of type 2 diabetes mellitus. Nevertheless, the exact mechanisms of action, underlying…”
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Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals by Elbere, Ilze, Silamikelis, Ivars, Ustinova, Monta, Kalnina, Ineta, Zaharenko, Linda, Peculis, Raitis, Konrade, Ilze, Ciuculete, Diana Maria, Zhukovsky, Christina, Gudra, Dita, Radovica-Spalvina, Ilze, Fridmanis, Davids, Pirags, Valdis, Schiöth, Helgi B, Klovins, Janis

“…Metformin is a widely prescribed antihyperglycemic agent that has been also associated with multiple therapeutic effects in various diseases, including several…”
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A novel EDA variant causing X-linked hypohidrotic ectodermal dysplasia: Case report by Alksere, Baiba, Kornejeva, Liene, Grinfelde, Ieva, Dzalbs, Aigars, Enkure, Dace, Conka, Una, Andersone, Santa, Blumberga, Arita, Nikitina-Zake, Liene, Kangare, Liga, Radovica-Spalvina, Ilze, Vasiljeva, Inta, Gailite, Linda, Erenpreiss, Juris, Fodina, Violeta

“…Hereditary ectodermal dysplasias are a complex group of inherited disorders characterised by abnormalities in two or more ectodermal derivatives (skin, nails,…”
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Case report: recurrent pituitary adenoma has increased load of somatic variants by Peculis, Raitis, Balcere, Inga, Radovica-Spalvina, Ilze, Konrade, Ilze, Caune, Olivija, Megnis, Kaspars, Rovite, Vita, Stukens, Janis, Nazarovs, Jurijs, Breiksa, Austra, Kiecis, Aigars, Silamikelis, Ivars, Pirags, Valdis, Klovins, Janis

“…Pituitary adenomas (PA) have an increased potential for relapse in one to 5 years after resection. In this study, we investigated the genetic differences in…”
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The effects of ibuprofen on activated sludge: Shift in bacterial community structure and resistance to ciprofloxacin by Davids, Madars, Gudra, Dita, Radovica-Spalvina, Ilze, Fridmanis, Davids, Bartkevics, Vadims, Muter, Olga

“…[Display omitted] •Ibuprofen (IBP) above 50mg/L inhibits an oxygen demand in the activated sludge (AS).•Selective pressure of IBP led to dominance of…”
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Removal of pharmaceuticals from municipal wastewaters at laboratory scale by treatment with activated sludge and biostimulation by Muter, Olga, P\erkons, Ingus, Selga, Turs, Berzins, Andrejs, Gudra, Dita, Radovica-Spalvina, Ilze, Fridmanis, Davids, Bartkevics, Vadims

“…Municipal wastewater containing 21 pharmaceutical compounds, as well as activated sludge obtained from the aeration tank of the same wastewater treatment plant…”
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Ryegrass mottle virus complete genome determination and development of infectious cDNA by combining two methods- 3' RACE and RNA-Seq by Ina Balke, Ivars Silamikelis, Ilze Radovica-Spalvina, Vilija Zeltina, Gunta Resevica, Davids Fridmanis, Andris Zeltins

“…Ryegrass mottle virus (RGMoV; genus: Sobemovirus) is a single-stranded positive RNA virus with a 30 nm viral particle size. It exhibits T = 3 symmetry with 180…”
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Single nucleotide polymorphisms in the intergenic region between metformin transporter OCT2 and OCT3 coding genes are associated with short-term response to metformin monotherapy in type 2 diabetes mellitus patients by Zaharenko, Linda, Kalnina, Ineta, Geldnere, Kristine, Konrade, Ilze, Grinberga, Solveiga, Židzik, Jozef, Javorský, Martin, Lejnieks, Aivars, Nikitina-Zake, Liene, Fridmanis, Davids, Peculis, Raitis, Radovica-Spalvina, Ilze, Hartmane, Dace, Pugovics, Osvalds, Tkáč, Ivan, Klimčáková, Lucia, Pīrāgs, Valdis, Klovins, Janis

“…Objective(s) High variability in clinical response to metformin is often observed in type 2 diabetes (T2D) patients, and it highlights the need for…”
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Next-generation-sequencing-based identification of familial hypercholesterolemia-related mutations in subjects with increased LDL-C levels in a latvian population by Radovica-Spalvina, Ilze, Latkovskis, Gustavs, Silamikelis, Ivars, Fridmanis, Davids, Elbere, Ilze, Ventins, Karlis, Ozola, Guna, Erglis, Andrejs, Klovins, Janis

“…Familial hypercholesterolemia (FH) is one of the commonest monogenic disorders, predominantly inherited as an autosomal dominant trait. When untreated, it…”
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Overview of Neuromuscular Disorder Molecular Diagnostic Experience for the Population of Latvia by Lace, Baiba, Micule, Ieva, Kenina, Viktorija, Setlere, Signe, Strautmanis, Jurgis, Kazaine, Inese, Taurina, Gita, Murmane, Daiga, Grinfelde, Ieva, Kornejeva, Liene, Krumina, Zita, Sterna, Olga, Radovica-Spalvina, Ilze, Vasiljeva, Inta, Gailite, Linda, Stavusis, Janis, Livcane, Diana, Kidere, Dita, Malniece, Ieva, Inashkina, Inna

“…Background and ObjectivesGenetic testing has become an integral part of health care, allowing the confirmation of thousands of hereditary diseases, including…”
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FIT test-systems for mega-scale gut microbiome testing by Gudra, Dita, Fridmanis, Davids, Klovins, Janis, Skenders, Girts, Silamikelis, Ivars, Radovica-Spalvina, Ilze, Peculis, Raitis, Kalnina, Ineta, Elbere, Ilze, Hultcrantz, Rolf, Leja, Marcis, Engstrand, Lars

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Extracellular Vesicles—A Source of RNA Biomarkers for the Detection of Breast Cancer in Liquid Biopsies by Zayakin, Pawel, Sadovska, Lilite, Eglītis, Kristaps, Romanchikova, Nadezhda, Radoviča-Spalviņa, Ilze, Endzeliņš, Edgars, Liepniece-Karele, Inta, Eglītis, Jānis, Linē, Aija

“…Over the past decade, extracellular vesicles (EVs) have emerged as a promising source of cancer-derived RNAs for liquid biopsies. However, blood contains a…”
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A novel EDA variant causing X-linked hypohidrotic ectodermal dysplasia: Case report by Alksere, Baiba, Kornejeva, Liene, Grinfelde, Ieva, Dzalbs, Aigars, Enkure, Dace, Conka, Una, Andersone, Santa, Blumberga, Arita, Nikitina-Zake, Liene, Kangare, Liga, Radovica-Spalvina, Ilze, Vasiljeva, Inta, Gailite, Linda, Erenpreiss, Juris, Fodina, Violeta

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