Search Results - "Radovani, Ernest"
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C2H2 zinc finger proteins greatly expand the human regulatory lexicon
Published in Nature biotechnology (01-05-2015)“…Comprehensive analysis of the binding specificities of C2H2 zinc finger proteins reveals their DNA recognition code. Cys2-His2 zinc finger (C2H2-ZF) proteins…”
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Multiparameter functional diversity of human C2H2 zinc finger proteins
Published in Genome research (01-12-2016)“…C2H2 zinc finger proteins represent the largest and most enigmatic class of human transcription factors. Their C2H2-ZF arrays are highly variable, indicating…”
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3
Regulation of histone gene transcription in yeast
Published in Cellular and molecular life sciences : CMLS (01-02-2014)“…Histones are the primary protein component of chromatin, the mixture of DNA and proteins that packages the genetic material in eukaryotes. Large amounts of…”
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The Carboxyl Terminus of Rtt109 Functions in Chaperone Control of Histone Acetylation
Published in Eukaryotic Cell (01-05-2013)“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Identification of a BET Family Bromodomain/Casein Kinase II/TAF-Containing Complex as a Regulator of Mitotic Condensin Function
Published in Cell reports (Cambridge) (01-03-2014)“…Condensin is a central regulator of mitotic genome structure with mutants showing poorly condensed chromosomes and profound segregation defects. Here, we…”
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Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors
Published in Molecular cell (02-02-2017)“…Networks of coordinated alternative splicing (AS) events play critical roles in development and disease. However, a comprehensive knowledge of the factors that…”
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A structural approach reveals how neighbouring C2H2 zinc fingers influence DNA binding specificity
Published in Nucleic acids research (30-10-2015)“…Development of an accurate protein-DNA recognition code that can predict DNA specificity from protein sequence is a central problem in biology. C2H2 zinc…”
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The amino acid sensor GCN2 suppresses terminal oligopyrimidine (TOP) mRNA translation via La-related protein 1 (LARP1)
Published in The Journal of biological chemistry (01-09-2022)“…La-related protein 1 (LARP1) has been identified as a key translational inhibitor of terminal oligopyrimidine (TOP) mRNAs downstream of the nutrient sensing…”
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Protein-protein and Protein-DNA Interactions of the Human C2H2 Zinc Finger Proteins
Published 01-01-2019“…TFs (transcription factors) bind DNA in a sequence specific manner and regulate transcription. Humans encode ∼1600 TFs, which have been identified almost…”
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Dissertation -
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Conserved Asf1–importin β physical interaction in growth and sexual development in the ciliate Tetrahymena thermophila
Published in Journal of proteomics (06-12-2013)“…How the eukaryotic cell specifies distinct chromatin domains is a central problem in molecular biology. The ciliate protozoan Tetrahymena thermophila features…”
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Journal Article