Search Results - "Radossi, P"

Multiplex ligation‐dependent probe amplification as first mutation screening for large deletions and duplications in haemophilia by Belvini, D., Salviato, R., Radossi, P., Tagariello, G.

“…Introduction Molecular characterization has shown a wide mutational spectrum underlying haemophilia A (HA) and haemophilia B (HB). Different molecular assays…”
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Non-Compartment and compartmental pharmacokinetics, efficacy, and safety of Kedrion FIX concentrate by Castaman, G., Borchiellini, A., Santagostino, E., Radossi, P., Aksu, S., Yilmaz, M., Serban, M., Uscatescu, V., Truica, C., Fasulo, M.R., Mancuso, M.E., Paladino, E., Valpreda, A., Guarnieri, C., Macchia, R., Scarpellini, M., Mathew, P., Morfini, M.

“…An open-label phase II, multicenter clinical trial was conducted at 11  Haemophilia Centres in  Italy, Romania, and Turkey, to evaluate the pharmacokinetics…”
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Comorbidities in persons with haemophilia aged 60 years or more compared with age‐matched people from the general population by Marchesini, E., Oliovecchio, E., Coppola, A., Santagostino, E., Radossi, P., Castaman, G., Valdrè, L., Santoro, C., Tagliaferri, A., Ettorre, C., Zanon, E., Barillari, G., Cantori, I., Caimi, T. M., Sottilotta, G., Iorio, A., Mannucci, P. M.

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Effects of secondary prophylaxis started in adolescent and adult haemophiliacs by TAGLIAFERRI, A., FRANCHINI, M., COPPOLA, A., RIVOLTA, G. F., SANTORO, C., ROSSETTI, G., FEOLA, G., ZANON, E., DRAGANI, A., IANNACCARO, P., RADOSSI, P., MANNUCCI, P. M.

“…While primary prophylaxis is a well‐established and recommended method of care delivery for children with severe haemophilia, fewer studies have documented the…”
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Correlation between FIX genotype and pharmacokinetics of Nonacog alpha according to a multicentre Italian study by Morfini, M., Dragani, A., Paladino, E., Radossi, P., Di Minno, G., Mazzucconi, M. G., Rossetti, G., Barillari, G., Napolitano, M., Tagariello, G.

“…Introduction Pharmacokinetic (PK) studies on recombinant FIX concentrate, Nonacog alpha, were conducted with different sampling time designs which gave rise to…”
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Total ankle replacement for end-stage arthropathy in patients with haemophilia by RADOSSI, P., BISSON, R., MUNARI, F., RISATO, R., TASSINARI, C., SARTORI, R., TAGARIELLO, G.

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F8 gene mutation profile and ITT response in a cohort of Italian haemophilia A patients with inhibitors by SALVIATO, R., BELVINI, D., RADOSSI, P., SARTORI, R., PIEROBON, F., ZANOTTO, D., ZANON, E., CASTAMAN, G., GANDINI, G., TAGARIELLO, G.

“…Anti factor VIII (FVIII) antibodies represent the main complication of replacement therapy in severe cases of haemophilia and most patients with inhibitor have…”
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Factor VIII gene intron 1 inversion: lower than expected prevalence in Italian haemophiliac severe patients by Salviato, R., Belvini, D., Radossi, P., Tagariello, G.

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One-stage replacement of infected knee prosthesis in a patient with haemophilia A and high titre of inhibitors by SARTORI, R., BISSON, R., BAARS, G. W., PETRIS, U., RADOSSI, P., RISATO, R., TASSINARI, C., TAGARIELLO, G.

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Prenatal diagnosis of haemophilia A by using intron 1 inversion detection by SALVIATO, R., BELVINI, D., ZANOTTO, D., DI GAETANO, R., RADOSSI, P., SARTORI, R., TASSINARI, C., TAGARIELLO, G.

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Concurrent total hip and knee replacements in a patient with haemophilia with inhibitors using recombinant factor VIIa by continuous infusion by Tagariello, G., Bisson, R., Radossi, P., Petris, U., Zanardo, G., De Biasi, E., Risato, R., Polese, F., Davoli, P. G.

“…The introduction of activated recombinant factor VIIa (rFVIIa) has allowed elective surgery to be safely performed in haemophiliacs with inhibitors. The main…”
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Persistence of parvovirus B19 DNA in synovium of patients with haemophilic arthritis by Zakrzewska, K., Azzi, A., De Biasi, E., Radossi, P., De Santis, R., Davoli, P.G., Tagariello, G.

“…A progressive arthropathy develops commonly in haemophiliacs and its pathogenesis is not fully understood. Human parvovirus B19 has been associated with…”
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Intra-articular rifamycin in haemophilic arthropathy by Radossi, P., Baggio, R., Petris, U., Biasi, E. De, Risato, R., Davoli, P. G., Tagariello, G.

“…Synoviorthesis is the intra‐articular injection of chemical or radioactive substances able to produce fibrosis of hypertrophied synovium, which has proved…”
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High incidence of anti-FVIII antibodies against non-coagulant epitopes in haemophilia A patients: a possible role for the half-life of transfused FVIII by Dazzi, F, Tison, T, Vianello, F, Radossi, P, Zerbinati, P, Carraro, P, Poletti, A, Girolami, A

“…The occurrence of antibodies (Abs) capable of inhibiting factor VIII (FVIII) coagulant activity is a severe complication in haemophilia A, leading to the…”
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Hepatitis C virus quasispecies in the natural course of HCV-related disease in patients with haemophilia by Tagariello, G., Gerotto, M., Pontisso, P., Belvini, D., Salviato, R., Radossi, P., Alberti, A.

“…Patients with haemophilia show high prevalence of hepatitis C infection but low rate of progressive liver disease when they are not co‐infected with HIV. The…”
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Large FVIII gene deletion confers very high risk of inhibitor development in three related severe haemophiliacs by SALVIATO, R., BELVINI, D., ARE, A., RADOSSI, P., TAGARIELLO, G.

“…Haemophilia A displays a broad heterogeneity of genetic defects and of clinical severity. Inhibitor development is the main complication of replacement therapy…”
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Recombinant FVIIa (NovoSeven) continuous infusion and total hip replacement in patients with haemophilia and high titre of inhibitors to FVIII: experience of two cases by Tagariello, G, De Biasi, E, Gajo, G B, Risato, R, Radossi, P, Davoli, P G, Traldi, A

“…In this report we describe our experience of total hip replacement in two patients with severe haemophilia A and high titres of inhibitors to FVIII. We used…”
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Rapid prenatal diagnosis of haemophilia by Belvini, D., Salviato, R., Are, A., Radossi, P., Tagariello, G.

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Homozygous patients with APC resistance may remain paucisymptomatic or asymptomatic during oral contraception by Girolami, A, Simioni, P, Girolami, B, Radossi, P

“…The effect of oral contraceptive therapy was studied in five patients with homozygous activated protein C resistance. Patients with this congenital…”
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Mortality and causes of death in Italian persons with haemophilia, 1990-2007 by TAGLIAFERRI, A., RIVOLTA, G. F., IORIO, A., OLIOVECCHIO, E., MANCUSO, M. E., MORFINI, M., ROCINO, A., MAZZUCCONI, M. G., FRANCHINI, M.

“…Although a number of studies have analysed so far the causes of death and the life expectancy in haemophilic populations, no investigations have been conducted…”
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