Search Results - "Radosavljevic, Gordana D"
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Interleukin‐33/ST2 axis promotes breast cancer growth and metastases by facilitating intratumoral accumulation of immunosuppressive and innate lymphoid cells
Published in International journal of cancer (01-04-2014)“…The role of IL‐33/ST2 pathway in antitumor immunity is unclear. Using 4T1 breast cancer model we demonstrate time‐dependent increase of endogenous IL‐33 at…”
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Galectin-3 Deficiency Accelerates High-Fat Diet―Induced Obesity and Amplifies Inflammation in Adipose Tissue and Pancreatic Islets
Published in Diabetes (New York, N.Y.) (01-06-2013)“…Obesity-induced diabetes is associated with low-grade inflammation in adipose tissue and macrophage infiltration of islets. We show that ablation of galectin-3…”
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The Potential of Frog Skin-Derived Peptides for Development into Therapeutically-Valuable Immunomodulatory Agents
Published in Molecules (Basel, Switzerland) (13-12-2017)“…The aim of this article is to review the immunoregulatory actions of frog skin-derived peptides in order to assess their potential as candidates for…”
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Contrasting Roles of the Galectin-3 in the Schizophrenia Onset, Clinical Presentation, and Somatic Comorbidity
Published in Current topics in medicinal chemistry (01-01-2021)“…The role of the Galectin-3 (Gal-3) has already been explored in various somatic diseases, considering its engagement in infection, acute and chronic…”
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Synthesis, characterization, DNA/BSA-binding affinity and biological activity of dinuclear palladium(II) complexes with aromatic N-heterocyclic bridging ligand
Published in Journal of coordination chemistry (17-04-2024)“…Dinuclear palladium(II) complexes, [{Pd(en)Cl} 2 (μ-L)](NO 3 ) 2 (L is bridging ligand pirazine (Pd1), pyrimidine (Pd2), pyridazine (Pd3), phenazine (Pd4) and…”
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6
IL-33 receptor (ST2) deficiency downregulates myeloid precursors, inflammatory NK and dendritic cells in early phase of sepsis
Published in Journal of biomedical science (12-07-2018)“…Sepsis is a life-threatening disease mediated by profound disturbances in systemic inflammatory response to infection. IL-33 is multifunctional regulator of…”
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Influence of antipsychotics on metabolic syndrome risk in patients with schizophrenia
Published in Frontiers in psychiatry (25-07-2022)“…Objective Many studies so far have shown that antipsychotic therapy may have an effect on the development of metabolic syndrome in patients diagnosed with…”
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IL-33/ST2 axis in innate and acquired immunity to tumors
Published in Oncoimmunology (01-03-2012)“…Interleukin-33, a ligand for ST2/T1, has an important role in allergy, autoimmunity and inflammation. The role of IL-33/ST2 axis in cancer is not elucidated…”
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Interleukin-33 pretreatment promotes metastatic growth of murine melanoma by reducing the cytotoxic capacity of CD8+ T cells and enhancing regulatory T cells
Published in Cancer Immunology, Immunotherapy (01-08-2020)“…Interleukin-33 (IL-33) regulates innate and acquired immune response to pathogens, self-antigens and tumors. IL-33 effects on tumors depend on the dose and…”
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Characterization, modes of interactions with DNA/BSA biomolecules and anti-tumor activity of newly synthesized dinuclear platinum(II) complexes with pyridazine bridging ligand
Published in Journal of biological inorganic chemistry (01-02-2024)“…Platinum-based drugs are widely recognized efficient anti-tumor agents, but faced with multiple undesirable effects. Here, four dinuclear platinum(II)…”
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The organic ester O,O' -diethyl-( S,S )-ethylenediamine- N,N' -di-2-(3-cyclohexyl)propanoate dihydrochloride attenuates murine breast cancer growth and metastasis
Published in Oncotarget (15-06-2018)“…Pharmacological treatment of cancer is mostly limited by drug-toxicity and resistance. It has been noticed that new organic ester ligand, diethyl-(…”
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The role of regulatory T cells in the modulation of anti-tumor immune response
Published in Srpski arhiv za celokupno lekarstvo (01-03-2013)“…Regulatory T cells (Treg) represent a subset of CD4+T cells whose function is to suppress immune responses. Treg lymphocytes can be divided into two subsets:…”
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The Zn( S -pr-thiosal) 2 complex attenuates murine breast cancer growth by inducing apoptosis and G1/S cell cycle arrest
Published in Future medicinal chemistry (01-05-2020)“…We investigated the antitumor effects of zinc(II) complex with -propyl thiosalicylic acid [Zn( -pr-thiosal) ] in 4T1 murine breast cancer model. The Zn(…”
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An analog of the host-defense peptide hymenochirin-1B with potent broad-spectrum activity against multidrug-resistant bacteria and immunomodulatory properties
Published in Peptides (New York, N.Y. : 1980) (01-12-2013)“…•[E6k,D9k]hymenochirin-1B is active against MRSA and multidrug-resistant Acinetobacter baumannii and Stenotrophomonas maltophilia.•The peptide is active…”
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Angiogenic and lymphangiogenic profiles in histological variants of papillary thyroid carcinoma
Published in Polskie archiwum medycyny wewne̦trznej (30-06-2017)“…Papillary thyroid carcinoma (PTC) is a well‑differentiated tumor that occurs in several histological variants whose biological behaviors remain unclear…”
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The frog skin host-defense peptide frenatin 2.1S enhances recruitment, activation and tumoricidal capacity of NK cells
Published in Peptides (New York, N.Y. : 1980) (01-07-2017)“…•The frog skin-derived frenatin 2.1S promotes recruitment of cytotoxic NK cells.•Frenatin 2.1S enhances activational state and tumoricidal capacities of NK…”
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In vivo administration of the frog skin peptide frenatin 2.1S induces immunostimulatory phenotypes of mouse mononuclear cells
Published in Peptides (New York, N.Y. : 1980) (01-09-2015)“…•Frenatin 2.1S enhances activation state and homing capacity of mouse peritoneal Th1 type lymphocytes and NKT cells.•Frenatin 2.1S increases the percentage of…”
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Circulating and tissue galectin-1 and galectin-3 in colorectal carcinoma: association with clinicopathological parameters, serum CEA, IL-17 and IL23
Published in Journal of B.U. ON. (01-07-2016)“…Galectins are modulators of many processes critical for tumor progression and metastasis but their clinical significance is still unclear. The objective of…”
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Clinical significance of Cyclin D1, FGF3 and p21 protein expression in laryngeal squamous cell carcinoma
Published in Journal of B.U. ON. (01-10-2014)“…Laryngeal squamous cell carcinoma (LSCC) represents one of the most common cancers of the head and neck and the search for molecular markers is required for…”
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Galectin-3 is a regulator of metaflammation in adipose tissue and pancreatic islets
Published in Adipocyte (22-10-2013)“…The cells of the innate and adaptive immune systems have been implicated in the development of obesity-induced metaflammation and metabolic disorders including…”
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