Search Results - "Radonjic‐Hoesli, Susanne"

Eosinophils in skin diseases by Radonjic-Hoesli, Susanne, Brüggen, Marie-Charlotte, Feldmeyer, Laurence, Simon, Hans-Uwe, Simon, Dagmar

“…Eosinophil infiltration is a common finding in a broad spectrum of skin diseases, despite the fact that the skin is devoid of eosinophils under physiologic…”
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Adhesion-induced eosinophil cytolysis requires the receptor-interacting protein kinase 3 (RIPK3)–mixed lineage kinase-like (MLKL) signaling pathway, which is counterregulated by autophagy by Radonjic-Hoesli, Susanne, MD, Wang, Xiaoliang, PhD, de Graauw, Elisabeth, MD, Stoeckle, Christina, PhD, Styp-Rekowska, Beata, PhD, Hlushchuk, Ruslan, PhD, Simon, Dagmar, MD, Spaeth, Peter J., PhD, Yousefi, Shida, PhD, Simon, Hans-Uwe, MD, PhD

“…Background Eosinophils are a subset of granulocytes that can be involved in the pathogenesis of different diseases, including allergy. Their effector functions…”
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Dupilumab‐associated ocular surface disease is characterized by a shift from Th2/Th17 toward Th1/Th17 inflammation by Thormann, Kathrin, Lüthi, Anne‐Sophie, Deniau, Felix, Heider, Anja, Cazzaniga, Simone, Radonjic‐Hoesli, Susanne, Lehmann, Mathias, Schlapbach, Christoph, Herzog, Elio L., Kreuzer, Marco, Zinkernagel, Martin S., Akdis, Cezmi A., Zysset‐Burri, Denise C., Simon, Hans‐Uwe, Simon, Dagmar

“…Background Dupilumab is used for the treatment of atopic dermatitis (AD). Approximately one third of AD patients develop a dupilumab‐associated ocular surface…”
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Dupilumab normalizes correlates of lysosomal function in atopic dermatitis by Bürgler, Christina, Dutoit, Danielle, Radonjic‐Hoesli, Susanne, Thormann, Kathrin, Lehmann, Mathias, Yousefi, Shida, Simon, Hans‐Uwe, Simon, Dagmar

“…Background Atopic dermatitis (AD) is characterized by skin barrier dysfunction and immune dysregulation. Autophagy, which is important for the epidermal…”
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PPAR-γ regulates the effector function of human T helper 9 cells by promoting glycolysis by Bertschi, Nicole L., Steck, Oliver, Luther, Fabian, Bazzini, Cecilia, von Meyenn, Leonhard, Schärli, Stefanie, Vallone, Angela, Felser, Andrea, Keller, Irene, Friedli, Olivier, Freigang, Stefan, Begré, Nadja, Radonjic-Hoesli, Susanne, Lamos, Cristina, Gabutti, Max Philip, Benzaquen, Michael, Laimer, Markus, Simon, Dagmar, Nuoffer, Jean-Marc, Schlapbach, Christoph

“…T helper 9 (T H 9) cells promote allergic tissue inflammation and express the type 2 cytokines, IL-9 and IL-13, as well as the transcription factor, PPAR-γ…”
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Toxicity of Eosinophil MBP Is Repressed by Intracellular Crystallization and Promoted by Extracellular Aggregation by Soragni, Alice, Yousefi, Shida, Stoeckle, Christina, Soriaga, Angela B., Sawaya, Michael R., Kozlowski, Evelyne, Schmid, Inès, Radonjic-Hoesli, Susanne, Boutet, Sebastien, Williams, Garth J., Messerschmidt, Marc, Seibert, M. Marvin, Cascio, Duilio, Zatsepin, Nadia A., Burghammer, Manfred, Riekel, Christian, Colletier, Jacques-Philippe, Riek, Roland, Eisenberg, David S., Simon, Hans-Uwe

“…Eosinophils are white blood cells that function in innate immunity and participate in the pathogenesis of various inflammatory and neoplastic disorders. Their…”
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Trajectories of humoral and cellular immunity and responses to a third dose of mRNA vaccines against SARS-CoV-2 in patients with a history of anti-CD20 therapy by Sidler, Daniel, Born, Alexander, Schietzel, Simeon, Horn, Michael P, Aeberli, Daniel, Amsler, Jennifer, Möller, Burkhard, Njue, Linet M, Medri, Cesare, Angelillo-Scherrer, Anne, Borradori, Luca, Seyed Jafari, S. Morteza, Radonjic-Hoesli, Susanne, Chan, Andrew, Hoepner, Robert, Bacher, Ulrike, Mani, Laila-Yasmin, Iype, Joseena Mariam, Suter-Riniker, Franziska, Staehelin, Cornelia, Nagler, Michael, Hirzel, Cedric, Maurer, Britta, Moor, Matthias B

“…BackgroundThe majority of patients with B-cell-depleting therapies show compromised vaccination-induced immune responses. Herein, we report on the trajectories…”
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Successful treatment of refractory folliculitis decalvans with apremilast by Fässler, Mirjam, Radonjic-Hoesli, Susanne, Feldmeyer, Laurence, Imstepf, Valentina, Pelloni, Lorenzo, Yawalkar, Nikhil, de Viragh, Pierre A.

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Are blood cytokines reliable biomarkers of allergic disease diagnosis and treatment responses? by Radonjic-Hoesli, Susanne, Pavlov, Nikolay, Simon, Hans-Uwe, Simon, Dagmar

“…With the development of targeted therapies for allergic diseases, the need for biomarkers supporting disease diagnosis and management has increased. Recent…”
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Urticaria and Angioedema: an Update on Classification and Pathogenesis by Radonjic-Hoesli, Susanne, Hofmeier, Kathrin Scherer, Micaletto, Sara, Schmid-Grendelmeier, Peter, Bircher, Andreas, Simon, Dagmar

“…Urticaria is a common, mast cell-driven disease presenting with wheals or angioedema or both. In the last years, urticaria has increasingly attracted notice to…”
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IL-9 sensitizes human Th2 cells to pro-inflammatory IL-18 signals in atopic dermatitis by Schärli, Stefanie, Luther, Fabian, Di Domizio, Jeremy, Hillig, Christina, Radonjic-Hoesli, Susanne, Thormann, Kathrin, Simon, Dagmar, Møller Rønnstad, Amalie Thorsti, Ruge, Iben Frier, Fritz, Blaine G., Bjarnsholt, Thomas, Vallone, Angela, Kezic, Sanja, Menden, Michael P., Roesner, Lennart M., Werfel, Thomas, Thyssen, Jacob P., Eyerich, Stefanie, Gilliet, Michel, Bertschi, Nicole L., Schlapbach, Christoph

“…[Display omitted] T helper 2 (Th2) cells crucially contribute to the pathogenesis of atopic dermatitis (AD) by secreting high levels of IL-13 and IL-22. Yet,…”
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Novel Targeted Therapies for Eosinophil-Associated Diseases and Allergy by Radonjic-Hoesli, Susanne, Valent, Peter, Klion, Amy D, Wechsler, Michael E, Simon, Hans-Uwe

“…Eosinophil-associated diseases often present with life-threatening manifestations and/or chronic organ damage. Currently available therapeutic options are…”
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Characteristics of Dermatological Patients With Blood Eosinophilia: A Retrospective Analysis of 453 Patients by Radonjic-Hoesli, Susanne, Martignoni, Zora, Cazzaniga, Simone, Furrer, Dominique Isabel, Simon, Hans-Uwe, Bürgler, Christina, Simon, Dagmar

“…Skin diseases associated with blood or tissue eosinophilia are common. Because these have various clinical manifestations, making the correct diagnosis can be…”
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Tu1114 Familial Eosinophilic Esophagitis (EoE) Uncovers a New EoE-Like Syndrome Without Tissue Eosinophilia by Straumann, Alex, Blanchard, Carine, Bussmann, Christian, Radonjic-Hoesli, Susanne, Hruz, Petr, Safroneeva, Ekaterina, Schoepfer, Alain, Simon, Dagmar, Simon, Hans-Uwe

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Eosinophils by Radonjic-Hösli, Susanne, Simon, Hans-Uwe

“…In 1846, T. Wharton-Jones described a coarsely granular stage in the development of granulocytic cells in animal and human blood. Shortly thereafter, Max…”
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Toxicity of Eosinophil MBP Is Repressed by Intracellular Crystallization and Promoted by Extracellular Aggregation by Soragni, Alice, Yousefi, Shida, Stoeckle, Christina, Soriaga, Angela B., Sawaya, Michael R., Kozlowski, Evelyne, Schmid, Inès, Radonjic-Hoesli, Susanne, Boutet, Sebastien, Williams, Garth J., Messerschmidt, Marc, Seibert, M.  Marvin, Cascio, Duilio, Zatsepin, Nadia A., Burghammer, Manfred, Riekel, Christian, Colletier, Jacques-Philippe, Riek, Roland, Eisenberg, David S., Simon, Hans-Uwe

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Toxicity of Eosinophil MBP Is Repressed by Intracellular Crystallization and Promoted by Extracellular Aggregation by Soragni, Alice, Yousefi, Shida, Stoeckle, Christina, Soriaga, Angela B., Sawaya, Michael R., Kozlowski, Evelyne, Schmid, Inès, Radonjic-Hoesli, Susanne, Boutet, Sebastien, Williams, Garth J., Messerschmidt, Marc, Seibert, M. Marvin, Cascio, Duilio, Zatsepin, Nadia A., Burghammer, Manfred, Riekel, Christian, Colletier, Jacques-Philippe, Riek, Roland, Eisenberg, David S., Simon, Hans-Uwe

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Successful treatment of refractory folliculitis decalvans with apremilast by Fässler, Mirjam, Radonjic-Hoesli, Susanne, Feldmeyer, Laurence, Imstepf, Valentina, Pelloni, Lorenzo, Yawalkar, Nikhil, de Viragh, Pierre A

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