Search Results - "Radoja, S"

Tumor-Infiltrating Macrophages Induce Apoptosis in Activated CD8+ T Cells by a Mechanism Requiring Cell Contact and Mediated by Both the Cell-Associated Form of TNF and Nitric Oxide by Saio, Masanao, Radoja, Sasa, Marino, Mike, Frey, Alan B

“…We have investigated the ability of different cells present in murine tumors to induce apoptosis of activated CD8(+) T cells in vitro. Tumor cells do not…”
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CD8+ Tumor-Infiltrating T Cells Are Deficient in Perforin-Mediated Cytolytic Activity Due to Defective Microtubule-Organizing Center Mobilization and Lytic Granule Exocytosis by Radoja, Sasa, Saio, Masanao, Schaer, David, Koneru, Mythili, Vukmanovic, Stanislav, Frey, Alan B

“…Tumor-infiltrating lymphocytes (TIL) are well known to be functionally impaired typified by the inability to lyse cognate tumor cells in vitro. We have…”
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Cancer-induced defective cytotoxic T lymphocyte effector function: another mechanism how antigenic tumors escape immune-mediated killing by Radoja, S, Frey, A B

“…The notion that a deficit in immune cell functions permits tumor growth has received experimental support with the discovery of several different biochemical…”
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T-cell receptor signaling events triggering granule exocytosis by Radoja, Sasa, Frey, Alan B, Vukmanovic, Stanislav

“…T-cell receptor (TCR) engagement by antigen results in proliferation, differentiation and cytokine secretion. In the CD8+ T-cell subset, TCR triggering also…”
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CD8+ Tumor-Infiltrating Lymphocytes Are Primed for Fas-Mediated Activation-Induced Cell Death But Are Not Apoptotic In Situ by Radoja, Sasa, Saio, Masanao, Frey, Alan B

“…Induction of Fas-mediated activation-induced cell death in antitumor T cells has been hypothesized to permit tumor escape from immune destruction. Several…”
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Activation of primary T lymphocytes results in lysosome development and polarized granule exocytosis in CD4 super(+) and CD8 super(+) subsets, whereas expression of lytic molecules confers cytotoxicity to CD8 super(+) T cells by Shen, D T, Ma, JSY, Mather, J, Vukmanovic, S, Radoja, S

“…Lytic granule exocytosis is the major cytotoxic mechanism used by CD8 super(+) cytotoxic lymphocytes. CD8 super(+) T cells acquire this effector function in…”
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Mice Bearing Late-Stage Tumors Have Normal Functional Systemic T Cell Responses In Vitro and In Vivo by Radoja, Sasa, Rao, T. Dharma, Hillman, Deborah, Frey, Alan B

“…Immune suppression in tumor-bearing hosts is considered to be one factor causally associated with the growth of antigenic tumors. Support for this hypothesis…”
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Tumor-Infiltrating Macrophages Induce Apoptosis in Activated CD8 super(+) T Cells by a Mechanism Requiring Cell Contact and Mediated by Both the Cell- Associated Form of TNF and Nitric Oxide by Saio, M, Radoja, S, Marino, M, Frey, AB

“…We have investigated the ability of different cells present in murine tumors to induce apoptosis of activated CD8 super(+) T cells in vitro. Tumor cells do not…”
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CD8 super(+) Tumor-Infiltrating Lymphocytes Are Primed for Fas-Mediated Activation-Induced Cell Death But Are Not Apoptotic In Situ by Radoja, S, Saio, M, Frey, AB

“…Induction of Fas-mediated activation-induced cell death in antitumor T cells has been hypothesized to permit tumor escape from immune destruction. Several…”
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CD8 super(+) Tumor-Infiltrating T Cells Are Deficient in Perforin-Mediated Cytolytic Activity Due to Defective Microtubule-Organizing Center Mobilization and Lytic Granule Exocytosis by Radoja, S, Saio, M, Schaer, D, Koneru, M, Vukmanovic, S, Frey, AB

“…Tumor-infiltrating lymphocytes (TIL) are well known to be functionally impaired typified by the inability to lyse cognate tumor cells in vitro. We have…”
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DNA architecture and transcriptional regulation of the Escherichia coli penicillin amidase ( pac) gene by Stojćević, Nataša, Morić, Ivana, Begović, Jelena, Radoja, Saša, Konstantinović, Miroslav

“…The transcriptional regulation of Escherichia coli ATCC11105 penicillin amidase ( pac) gene was studied by modifying DNA sequences responsible for promoter…”
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DNA region responsible for transcriptional regulation of the Escherichia coli penicillin amidase (pac) gene by CRP and PAA by Radoja, S, Francetić, O, Stojićević, N, Morić, I, Glisin, V, Konstantinović, M

“…Transcriptional regulation of Escherichia coli ATCC11105 penicillin amidase gene (pac) by cAMP receptor protein (CRP) and phenylacetic acid (PAA) was studied…”
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