Search Results - "Radke, Anna"

Sex Differences in Binge‐Like and Aversion‐Resistant Alcohol Drinking in C57BL/6J Mice by Sneddon, Elizabeth A., White, Robert D., Radke, Anna K.

“…Background Alcohol use disorder is characterized by compulsive alcohol intake, or drinking despite negative consequences. Previous studies have shown that…”
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Increased Responding for Alcohol and Resistance to Aversion in Female Mice by Sneddon, Elizabeth A., Ramsey, Olivia R., Thomas, Annemarie, Radke, Anna K.

“…Background More women are being diagnosed with alcohol use disorder (AUD), are increasing the amount of alcohol they are drinking, and are partaking in risky…”
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Opioid withdrawal: role in addiction and neural mechanisms by Monroe, Sean C., Radke, Anna K.

“…Withdrawal from opioids involves a negative affective state that promotes maintenance of drug-seeking behavior and relapse. As such, understanding the…”
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Aversion-resistant fentanyl self-administration in mice by Monroe, Sean C., Radke, Anna K.

“…Rationale Animal models of compulsive drug use that continues despite negative consequences can be used to investigate the neural mechanisms of addiction…”
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Recent Perspectives on Sex Differences in Compulsion-Like and Binge Alcohol Drinking by Radke, Anna K, Sneddon, Elizabeth A, Frasier, Raizel M, Hopf, Frederic W

“…Alcohol use disorder remains a substantial social, health, and economic problem and problem drinking levels in women have been increasing in recent years…”
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Advances in understanding meso‐cortico‐limbic‐striatal systems mediating risky reward seeking by Piantadosi, Patrick T., Halladay, Lindsay R., Radke, Anna K., Holmes, Andrew

“…The risk of an aversive consequence occurring as the result of a reward‐seeking action can have a profound effect on subsequent behavior. Such aversive events…”
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Removal of the ovaries suppresses ethanol drinking and promotes aversion-resistance in C57BL/6J female mice by Sneddon, Elizabeth A., Masters, Brianna M., Shi, Haifei, Radke, Anna K.

“…Rationale Female rodents consume more ethanol (EtOH) than males and exhibit greater aversion-resistant drinking in some paradigms. Ovarian hormones promote…”
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Cortical GluN2B deletion attenuates punished suppression of food reward-seeking by Radke, Anna K., Nakazawa, Kazu, Holmes, Andrew

“…Rationale Compulsive behavior, which is a hallmark of psychiatric disorders such as addiction and obsessive-compulsive disorder, engages corticostriatal…”
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NMDA receptor deletion on dopamine neurons disrupts visual discrimination and reversal learning by Radke, Anna K., Zweifel, Larry S., Holmes, Andrew

“…[Display omitted] •NMDARs on DAT + neurons were genetically deleted in mice.•Mice were tested in a pairwise discrimination and reversal learning…”
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The contribution of medium spiny neuron subtypes in the nucleus accumbens core to compulsive-like ethanol drinking by Sneddon, Elizabeth A., Schuh, Kristen M., Frankel, John W., Radke, Anna K.

“…Compulsive alcohol use, or drinking that persists despite negative or aversive consequences, is a defining characteristic of alcohol use disorder. Here,…”
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Contributions of nucleus accumbens dopamine to cognitive flexibility by Radke, Anna K., Kocharian, Adrina, Covey, Dan P., Lovinger, David M., Cheer, Joseph F., Mateo, Yolanda, Holmes, Andrew

“…There is a compelling evidence that midbrain dopamine (DA) neurons and their projections to the ventral striatum provide a mechanism for motivating…”
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Increased Dopamine Receptor Activity in the Nucleus Accumbens Shell Ameliorates Anxiety during Drug Withdrawal by RADKE, Anna K, GEWIRTZ, Jonathan C

“…A number of lines of evidence suggest that negative emotional symptoms of withdrawal involve reduced activity in the mesolimbic dopamine system. This study…”
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Additive influences of acute early life stress and sex on vulnerability for aversion‐resistant alcohol drinking by Radke, Anna K., Held, Isabel T., Sneddon, Elizabeth A., Riddle, Collin A., Quinn, Jennifer J.

“…Acute early life stress (ELS) alters stress system functioning in adulthood and increases susceptibility to posttraumatic stress disorder (PTSD) and alcohol…”
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Improved visual discrimination learning in mice with partial 5-HT2B gene deletion by Radke, Anna K., Piantadosi, Patrick T., Uhl, George R., Hall, F. Scott, Holmes, Andrew

“…•5-HT2B receptors are implicated in cognitive function and regulation of serotonin signaling.•Male mice with partial Htr2b deletion were tested for…”
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Greater resistance to footshock punishment in female C57BL/6J mice responding for ethanol by Sneddon, Elizabeth A., Fennell, Kaila A., Bhati, Sachi, Setters, Joshua E., Schuh, Kristen M., DeMedio, Jenelle N., Arnold, Brandon J., Monroe, Sean C., Quinn, Jennifer J., Radke, Anna K.

“…Background One characteristic of alcohol use disorder is compulsive drinking or drinking despite negative consequences. When quinine is used to model such…”
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Cholinergic mu-opioid receptor deletion alters reward preference and aversion-resistance by Beane, Cambria R., Lewis, Delainey G., Bruns VI, Nicolaus, Pikus, Kat L., Durfee, Mary H., Zegarelli, Roman A., Perry, Thomas W., Sandoval, Oscar, Radke, Anna K.

“…The endogenous opioid system has been implicated in alcohol consumption and preference in both humans and animals. The mu opioid receptor (MOR) is expressed on…”
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An analysis of IL-8, IL-6, TNF-α cytokines in breast milk and the relationship between milk nutrients and clinical diagnosis by Gadzała-Kopciuch, Renata, Kuźniewska-Radke, Anna, Railean, Viorica, Pomastowski, Paweł, Bernatowicz-Łojko, Urszula, Sinkiewicz-Darol, Elena, Buszewski, Bogusław

“…The aim of this study was to assess cytokine levels (interleukin - IL-6, interleukin - IL-8, interferon gamma - IFN-γ, tumor necrosis factor - TNF-α) in breast…”
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Sex chromosome and gonadal hormone contributions to binge-like and aversion-resistant ethanol drinking behaviors in Four Core Genotypes mice by Sneddon, Elizabeth A, Masters, Brianna M, Ream, Kiara D, Fennell, Kaila A, DeMedio, Jenelle N, Cash, Miranda M, Hollingsworth, Brynn P, Pandrangi, Sai, Thach, Chloe M, Shi, Haifei, Radke, Anna K

“…While substantial research has focused on the contribution of sex hormones to driving elevated levels of alcohol drinking in female rodents, fewer studies have…”
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Crossed high alcohol preferring mice exhibit aversion-resistant responding for alcohol with quinine but not footshock punishment by Sneddon, Elizabeth A., Schuh, Kristen M., Fennell, Kaila A., Grahame, Nicholas J., Radke, Anna K.

“…A symptom of alcohol use disorder (AUD) is compulsive drinking, or drinking that persists despite negative consequences. In mice, aversion-resistant models are…”
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Studying Sex Differences in Rodent Models of Addictive Behavior by Radke, Anna K, Sneddon, Elizabeth A, Monroe, Sean C

“…Animal models of addictive behaviors are useful for uncovering neural mechanisms involved in the development of dependence and for identifying risk factors for…”
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