Search Results - "Radinsky, R."

Paclitaxel Enhances the Effects of the Anti-Epidermal Growth Factor Receptor Monoclonal Antibody ImClone C225 in Mice with Metastatic Human Bladder Transitional Cell Carcinoma by INOUE, Keiji, SLATON, Joel W, PERROTTE, Paul, DAVIS, Darren W, BRUNS, Christiane J, HICKLIN, Daniel J, MCCONKEY, David J, SWEENEY, Paul, RADINSKY, Robert, DINNEY, Colin P. N

“…Previously we reported that when cells from the human transitional cell carcinoma cell line 253J B-V growing orthotopically within the bladder of athymic nude…”
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Anti-tumor activity of motesanib in a medullary thyroid cancer model by Coxon, A., Bready, J., Kaufman, S., Estrada, J., Osgood, T., Canon, J., Wang, L., Radinsky, R., Kendall, R., Hughes, P., Polverino, A.

“…Background: Medullary thyroid cancer (MTC) is frequently associated with mutations in the tyrosine kinase Ret and with increased expression of vascular…”
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Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression by Owen-Schaub, L B, Zhang, W, Cusack, J C, Angelo, L S, Santee, S M, Fujiwara, T, Roth, J A, Deisseroth, A B, Zhang, W W, Kruzel, E

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Molecular mechanisms for organ-specific colon carcinoma metastasis by Radinsky, R

“…The mechanistic basis of a metastatic cell's ability to proliferate in the parenchyma of certain organs and develop organ-specific metastases remains largely…”
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Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells by RADINSKY, R, RISIN, S, FAN, D, ZHONGYUN DONG, BIELENBERG, D, BUCANA, C. D, FIDLER, I. J

“…The purpose of this study was to determine whether production of liver metastasis by human colon carcinoma (HCC) cells depends on the response of tumor cells…”
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Cortical NOS inhibition raises the lower limit of cerebral blood flow-arterial pressure autoregulation by Jones, S C, Radinsky, C R, Furlan, A J, Chyatte, D, Perez-Trepichio, A D

“…The maintenance of constant cerebral blood flow (CBF) as arterial blood pressure is reduced, commonly referred to as CBF-pressure autoregulation, is typically…”
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Variability in the magnitude of the cerebral blood flow response and the shape of the cerebral blood flow: Pressure autoregulation curve during hypotension in normal rats by JONES, Stephen C, RADINSKY, Carol R, FURLAN, Anthony J, CHYATTE, Douglas, YINSHENG QU, EASLEY, Kirk A, PEREZ-TREPICHIO, Alejandro D

“…The maintenance of constant cerebral blood flow (CBF) as mean cerebral perfusion pressure (CPP) varies is commonly referred to as CBF-pressure autoregulation…”
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Panitumumab, a Fully Human Anti-EGFR Monoclonal Antibody, Augments Radiation Response in Xenograft Models of Upper Aerodigestive Tract Cancers by Kruser, T.J, Armstrong, E, Huang, S, Radinsky, R, Starnes, C, Freeman, D, Harari, P.M

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Cancer Therapeutics: Understanding the Mechanism of Action by Cattley, Russell C., Radinsky, Bert R.

“…An intended consequence of the significant investment to characterize the mammalian genome, and its alterations in neoplastic diseases, has been the discovery…”
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Genetic control of cancer metastasis by Fidler, I J, Radinsky, R

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Search for Genes That Suppress Cancer Metastasis by Fidler, Isaiah J., Radinsky, Robert

“…An editorial addresses Lee et al's report of the isolation of a novel gene termed KiSS-1 that is involved in controlling the metastatic poetntial of cancer. An…”
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Expression of Epidermal Growth Factor Receptor and Human Papillomavirus E6/E7 Proteins in Cervical Carcinoma Cells by Hu, Guiying, Mendelsohn, John, Andreeff, Michael, Liu, Wenbiao, Radinsky, Robert, Ellis, Lee M., Deisseroth, Albert B.

“…Background: Epidermal growth factor receptor (EGF-R) proteins are highly expressed in many tumors, including those of the cervix. We have observed previously…”
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Growth factors and their receptors in metastasis by Radinsky, R

“…The process of metastasis is not random. Rather, the outcome depends on the interaction of unique metastic cells with different organ microenvironments…”
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Organ-specific modulation of steady-state mdr gene expression and drug resistance in murine colon cancer cells by Dong, Z, Radinsky, R, Fan, D, Tsan, R, Bucana, C D, Wilmanns, C, Fidler, I J

“…The major cause of death from cancer is metastases that are resistant to conventional therapies. The resistance of metastatic tumor cells to chemotherapy can…”
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Nitric Oxide Synthase Inhibition Depresses the Height of the Cerebral Blood Flow-Pressure Autoregulation Curve During Moderate Hypotension by Jones, Stephen C., Easley, Kirk A., Radinsky, Carol R., Chyatte, Douglas, Furlan, Anthony J., Perez-Trepichio, Alejandro D.

“…Variations in the height of the CBF response to hypotension have been described recently in normal animals. The authors evaluated the effects of nitric oxide…”
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309 POSTER Fully human anti-HER3 mAb U3-1287 (AMG 888) demonstrates unique in vitro and in vivo activities versus other HER family inhibitors in NSCLC models by Treder, M, Ogbagabriel, S, Moor, R, Schulze-Horsel, U, Hettmann, T, Rothe, M, Radinsky, R, Freeman, D

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509 POSTER Efficacy of AMG 479, a fully human anti-IGF-1R monoclonal antibody, against xenograft models displaying genetic alterations in Ras/Raf, PI3K/PTEN and p53 pathways by Beltran, P.J, Moody, G, Mitchell, P, Le, Q, Belmontes, B, Cajulis, E, Chung, Y.A, Calzone, F, Radinsky, R

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Molecular determinants in the biology of liver metastasis by Radinsky, R, Ellis, L M

“…A primary goal of cancer research is an increased understanding of the molecular mechanisms mediating the process of cancer metastasis. Analyses of colon…”
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3019 POSTER Association of gene copy number (GCN) of the epidermal growth factor receptor (EGFr) and clinical outcome in patients (pts) with metastatic colorectal cancer (mCRC) treated with panitumumab monotherapy by Berlin, J, Hecht, J.R, Reiner, M, Mullenix, M, Suggs, S, Radinsky, R, Freeman, D, Amado, R.G, Meropol, N.J

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A rapid colorimetric in situ mRNA hybridization technique using hyperbiotinylated oligonucleotide probes for analysis of mdr1 in mouse colon carcinoma cells by Bucana, CD, Radinsky, R, Dong, Z, Sanchez, R, Brigati, DJ, Fidler, IJ

“…We describe the development of a rapid colorimetric in situ hybridization technique utilizing oligonucleotide probes labeled with six biotin molecules at the…”
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