Search Results - "Radhakrishnan, Rajesh Kumar"

1-Alkyl-(N,N-dimethylamino)pyridinium bromides: inhibitory effect on virulence factors of Candida albicans and on the growth of bacterial pathogens by SUNDARARAMAN, Muthuraman, RADHAKRISHNAN RAJESH KUMAR, VENKATESAN, Perumal, ILANGOVAN, Andivelu

“…A homologous series of 1-alkyl-(N,N-dimethylamino)pyridinium bromides, termed compounds 1-11, was synthesized and studied for antibacterial and antifungal…”
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Metabolic changes enhance necroptosis of type 2 diabetes mellitus mice infected with Mycobacterium tuberculosis by Vankayalapati, Abhinav, Durojaye, Olamipejo, Mukherjee, Tanmoy, Paidipally, Padmaja, Owusu-Afriyie, Bismark, Vankayalapati, Ramakrishna, Radhakrishnan, Rajesh Kumar

“…Previously, we found that Mycobacterium tuberculosis (Mtb) infection in type 2 diabetes mellitus (T2DM) mice enhances inflammatory cytokine production which…”
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IL-22 produced by type 3 innate lymphoid cells (ILC3s) reduces the mortality of type 2 diabetes mellitus (T2DM) mice infected with Mycobacterium tuberculosis by Tripathi, Deepak, Radhakrishnan, Rajesh Kumar, Sivangala Thandi, Ramya, Paidipally, Padmaja, Devalraju, Kamakshi Prudhula, Neela, Venkata Sanjeev Kumar, McAllister, Madeline Kay, Samten, Buka, Valluri, Vijaya Lakshmi, Vankayalapati, Ramakrishna

“…Previously, we found that pathological immune responses enhance the mortality rate of Mycobacterium tuberculosis (Mtb)-infected mice with type 2 diabetes…”
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Ornithine-A urea cycle metabolite enhances autophagy and controls Mycobacterium tuberculosis infection by Sivangala Thandi, Ramya, Radhakrishnan, Rajesh Kumar, Tripathi, Deepak, Paidipally, Padmaja, Azad, Abul K, Schlesinger, Larry S, Samten, Buka, Mulik, Sachin, Vankayalapati, Ramakrishna

“…Macrophages are professional phagocytes known to play a vital role in controlling Mycobacterium tuberculosis (Mtb) infection and disease progression. Here we…”
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Retraction Note: Ornithine-A urea cycle metabolite enhances autophagy and controls Mycobacterium tuberculosis infection by Sivangala Thandi, Ramya, Radhakrishnan, Rajesh Kumar, Tripathi, Deepak, Paidipally, Padmaja, Azad, Abul K., Schlesinger, Larry S., Samten, Buka, Mulik, Sachin, Vankayalapati, Ramakrishna

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Correction: IL-22 produced by type 3 innate lymphoid cells (ILC3s) reduces the mortality of type 2 diabetes mellitus (T2DM) mice infected with Mycobacterium tuberculosis by Tripathi, Deepak, Radhakrishnan, Rajesh Kumar, Thandi, Ramya Sivangala, Paidipally, Padmaja, Devalraju, Kamakshi Prudhula, Neela, Venkata Sanjeev Kumar, McAllister, Madeline Kay, Samten, Buka, Valluri, Vijaya Lakshmi, Vankayalapati, Ramakrishna

“…[This corrects the article DOI: 10.1371/journal.ppat.1008140.]…”
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Alcohol enhances type 1 interferon-α production and mortality in young mice infected with Mycobacterium tuberculosis by Tripathi, Deepak, Welch, Elwyn, Cheekatla, Satyanarayana Swamy, Radhakrishnan, Rajesh Kumar, Venkatasubramanian, Sambasivan, Paidipally, Padmaja, Van, Abhinav, Samten, Buka, Devalraju, Kamakshi P, Neela, Venkata Sanjeev Kumar, Valluri, Vijaya Lakshmi, Mason, Carol, Nelson, Steve, Vankayalapati, Ramakrishna

“…In the current study, we used a mouse model and human blood samples to determine the effects of chronic alcohol consumption on immune responses during…”
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Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stress by Kumar, Radhakrishnan Rajesh, Narasimhan, Madhusudhanan, Shanmugam, Gobinath, Hong, Jennifer, Devarajan, Asokan, Palaniappan, Sethu, Zhang, Jianhua, Halade, Ganesh V, Darley-Usmar, Victor M, Hoidal, John R, Rajasekaran, Namakkal S

“…Anomalies in myocardial structure involving myocyte growth, hypertrophy, differentiation, apoptosis, necrosis etc. affects its function and render cardiac…”
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Metabolites enhance innate resistance to human Mycobacterium tuberculosis infection by Tripathi, Deepak, Devalraju, Kamakshi Prudhula, Neela, Venkata Sanjeev Kumar, Mukherjee, Tanmoy, Paidipally, Padmaja, Radhakrishnan, Rajesh Kumar, Dozmorov, Igor, Vankayalapati, Abhinav, Ansari, Mohammad Soheb, Mallidi, Varalakshmi, Bogam, Anvesh Kumar, Singh, Karan P, Samten, Buka, Valluri, Vijaya Lakshmi, Vankayalapati, Ramakrishna

“…To determine the mechanisms that mediate resistance to Mycobacterium tuberculosis (M. tuberculosis) infection in household contacts (HHCs) of patients with…”
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Reduced thyroxine production in young household contacts of tuberculosis patients increases active tuberculosis disease risk by Devalraju, Kamakshi Prudhula, Tripathi, Deepak, Neela, Venkata Sanjeev Kumar, Paidipally, Padmaja, Radhakrishnan, Rajesh Kumar, Singh, Karan P, Ansari, Mohammad Soheb, Jaeger, Martin, Netea-Maier, Romana T, Netea, Mihai G, Park, Sunmi, Cheng, Sheue-Yann, Valluri, Vijaya Lakshmi, Vankayalapati, Ramakrishna

“…In the current study, we followed 839 household contacts (HHCs) of tuberculosis (TB) patients for 2 years and identified the factors that enhanced the…”
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Lung-resident CD3-NK1.1+CD69+CD103+ Cells Play an Important Role in Bacillus Calmette-Guérin Vaccine-Induced Protective Immunity against Mycobacterium tuberculosis Infection by Durojaye, Olamipejo, Vankayalapati, Abhinav, Paidipally, Padmaja, Mukherjee, Tanmoy, Vankayalapati, Ramakrishna, Radhakrishnan, Rajesh Kumar

“…Tissue-resident immune cells play important roles in local tissue homeostasis and infection control. There is no information on the functional role of…”
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CD11b+Ly6g+CD69+CD74+ cells produce interferon-α in Mycobacterium tuberculosis infected alcohol diet-fed mice by Mukherjee, Tanmoy, Tripathi, Ashutosh, Radhakrishnan, Rajesh Kumar, Vankayalapati, Abhinav, Vankayalapati, Ramakrishna, Tripathi, Deepak

“…Abstract Chronic alcohol consumption is associated with significant mortality and morbidity in people affected by Mycobacterium tuberculosis (Mtb) infection…”
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Phenotypic and functional characterization of lung resident lymphocytes of BCG vaccinated mice by McAllister, Madeline K, Tripathi, Deepak, Radhakrishnan, Rajesh Kumar, Thandi, Ramya Sivangala, Paidipally, Padmaja, Vankayalapati, Ramakrishna

“…Abstract Mycobacterium tuberculosis (Mtb) remains to be a leading cause of morbidity and mortality, causing an estimated 1.3 million deaths annually. It is…”
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Ornithine-A urea cycle metabolite enhances autophagy and controls Mycobacterium tuberculosis infection by Thandi, Ramya Sivangala, Radhakrishnan, Rajesh kumar, Tripathi, Deepak, Paidipally, Padmaja, Vankayalapati, Ramakrishna

“…Abstract Alveolar macrophages (AMs) are the first cells encountered by TB pathogen and serve as the primary defense against Mycobacterium tuberculosis (Mtb) in…”
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Prior Bacillus Calmette-Guérin (BCG) vaccination ameliorates the pathogenesis of Type 2 diabetes mellitus mice infected with Mycobacterium tuberculosis by Radhakrishnan, Rajesh Kumar, Tripathi, Deepak, Thandi, Ramya Sivangala, Paidipally, Padmaja, Vankayalapati, Ramakrishna

“…Abstract Previously, we found experimentally induced type 2 diabetes mellitus (T2DM) mice are highly susceptible to Mycobacterium tuberculosis (Mtb) infection…”
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Liver macrophages controls Mycobacterium tuberculosis growth by enhancing autophagy by Thandi, Ramya Sivangala, Tripathi, Deepak, Radhakrishnan, Rajesh Kumar, Paidipally, Padmaja, Vankayalapati, Ramakrishna

“…Abstract Alveolar macrophages are the first cells to come in contact with TB pathogen in lung, but unable to eliminate Mycobacterium tuberculosis (M. tb)…”
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BCG vaccination reduces the mortality of Mycobacterium tuberculosis -infected type 2 diabetes mellitus (T2DM) mice through the induction of CXCR3+ T-regulatory cells by Radhakrishnan, Rajesh Kumar, Thandi, Ramya Sivangala, Tripathi, Deepak, Paidipally, Padmaja, McAllister, Madeline, Mulik, Sachin, Samten, Buka, Vankayalapati, Ramakrishna

“…Abstract Diabetes is a significant risk factor for the development of active tuberculosis. In this study, we used mouse model of Streptozotocin/Nicotinamide…”
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A rho GDP dissociation inhibitor produced by a subset of T-regulatory cells enhances mitophagy in Mycobacterium tuberculosis infected human macrophages by Paidipally, Padmaja, Thandi, Ramya Sivangala, Radhakrishnan, Rajesh Kumar, McAllister, Madeline K, Samten, Buka, Vankayalapati, Ramakrishna, Tripathi, Deepak

“…Abstract Previously, we found that a Rho GDP dissociation inhibitor (D4GDI), produced by apoptotic T regulatory cells inhibit Mycobacterium tuberculosis (Mtb)…”
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Reductive Stress Causes Pathological Cardiac Remodeling and Diastolic Dysfunction by Shanmugam, Gobinath, Wang, Ding, Gounder, Sellamuthu S, Fernandes, Jolyn, Litovsky, Silvio H, Whitehead, Kevin, Radhakrishnan, Rajesh Kumar, Franklin, Sarah, Hoidal, John R, Kensler, Thomas W, Dell'Italia, Louis, Darley-Usmar, Victor, Abel, E Dale, Jones, Dean P, Ping, Peipei, Rajasekaran, Namakkal S

“…Redox homeostasis is tightly controlled and regulates key cellular signaling pathways. The cell's antioxidant response provides a natural defense against…”
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Interleukin-21 Regulates Natural Killer Cell Responses During Mycobacterium tuberculosis Infection by Paidipally, Padmaja, Tripathi, Deepak, Van, Abhinav, Radhakrishnan, Rajesh Kumar, Dhiman, Rohan, Venkatasubramanian, Sambasivan, Devalraju, Kamakshi P, Tvinnereim, Amy R, Valluri, Vijaya Lakshmi, Vankayalapati, Ramakrishna

“…Abstract Background In the current study, we determined the effects of interleukin (IL)-21 on human natural killer (NK) cells and monocyte responses during…”
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