Search Results - "Radhakrishnan, Dhwani"

The deubiquitinase OTUD1 regulates immunoglobulin production and proteasome inhibitor sensitivity in multiple myeloma by Vdovin, Alexander, Jelinek, Tomas, Zihala, David, Sevcikova, Tereza, Durech, Michal, Sahinbegovic, Hana, Snaurova, Renata, Radhakrishnan, Dhwani, Turi, Marcello, Chyra, Zuzana, Popkova, Tereza, Venglar, Ondrej, Hrdinka, Matous, Hajek, Roman, Simicek, Michal

“…Serum monoclonal immunoglobulin (Ig) is the main diagnostic factor for patients with multiple myeloma (MM), however its prognostic potential remains unclear…”
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Tuning CARs: recent advances in modulating chimeric antigen receptor (CAR) T cell activity for improved safety, efficacy, and flexibility by Celichowski, Piotr, Turi, Marcello, Charvátová, Sandra, Radhakrishnan, Dhwani, Feizi, Neda, Chyra, Zuzana, Šimíček, Michal, Jelínek, Tomáš, Bago, Juli Rodriguez, Hájek, Roman, Hrdinka, Matouš

“…Cancer immunotherapies utilizing genetically engineered T cells have emerged as powerful personalized therapeutic agents showing dramatic preclinical and…”
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Transcriptome Analysis of Diffuse Large B-Cell Lymphoma Cells Inducibly Expressing MyD88 L265P Mutation Identifies Upregulated CD44, LGALS3, NFKBIZ, and BATF as Downstream Targets of Oncogenic NF-κB Signaling by Turi, Marcello, Anilkumar Sithara, Anjana, Hofmanová, Lucie, Žihala, David, Radhakrishnan, Dhwani, Vdovin, Alexander, Knápková, Sofija, Ševčíková, Tereza, Chyra, Zuzana, Jelínek, Tomáš, Šimíček, Michal, Gullà, Annamaria, Anderson, Kenneth Carl, Hájek, Roman, Hrdinka, Matouš

“…During innate immune responses, myeloid differentiation primary response 88 (MyD88) functions as a critical signaling adaptor protein integrating stimuli from…”
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PB2397: TRANSCRIPTOME ANALYSIS OF DIFFUSE LARGE B‐CELL LYMPHOMA CELLS EXPRESSING MYD88 L265P REVEALS CD44, LGALS3, NFKBIZ AND BATF AS DOWNSTREAM TARGETS OF ONCOGENIC NF‐ΚB SIGNALING by Turi, Marcello, Anilkumar Sithara, Anjana, Hofmanová, Lucie, Žihala, David, Radhakrishnan, Dhwani, Vdovin, Alexander, Knápková, Sofija, Ševčíková, Tereza, Chyra, Zuzana, Jelínek, Tomas, Šimíček, Michal, Gullà, Annamaria, Anderson, Kenneth, Hájek, Roman, Hrdinka, Matous

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Restoration of β-GC trafficking improves the lysosome function in Gaucher disease by Patel, Saloni, Radhakrishnan, Dhwani, Kumari, Darpan, Bhansali, Priyanka, Setty, Subba Rao Gangi

“…Lysosomes function as a primary site for catabolism and cellular signaling. These organelles digest a variety of substrates received through endocytosis,…”
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Deubiquitinase BAP1 is crucial for surface expression of T cell receptor (TCR) complex, T cell-B cell conjugate formation, and T cell activation by Radhakrishnan, Dhwani, Kotulová, Jana, Hofmanová, Lucie, Sithara, Anjana Anilkumar, Turi, Marcello, Žihala, David, Ďurech, Michal, Vrána, Jan, Uleri, Valeria, Niederlova, Veronika, Stepanek, Ondrej, Chyra, Zuzana, Jelínek, Tomáš, Hájek, Roman, Hrdinka, Matous

“…The adaptive immune response critically hinges on the functionality of T cell receptors (TCRs), governed by complex molecular mechanisms, including…”
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