Search Results - "Radhakrishna, M."
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Genomic perspective of triazole resistance in clinical and environmental Aspergillus fumigatus isolates without cyp51A mutations
Published in Fungal genetics and biology (01-11-2019)“…•Widespread increase in azole resistant A. fumigatus is a matter of global concern.•Non-cyp51A mediated mechanism of azole resistance has been gaining…”
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Vaccine efficacy against persistent human papillomavirus (HPV) 16/18 infection at 10 years after one, two, and three doses of quadrivalent HPV vaccine in girls in India: a multicentre, prospective, cohort study
Published in The lancet oncology (01-11-2021)“…A randomised trial designed to compare three and two doses of quadrivalent human papillomavirus (HPV) vaccine in adolescent girls in India was converted to a…”
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Evaluation of immune response to single dose of quadrivalent HPV vaccine at 10-year post-vaccination
Published in Vaccine (04-01-2023)“…The recent World Health Organization recommendation supporting single-dose of HPV vaccine will significantly reduce programmatic cost, mitigate the supply…”
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4
Crustal structure along the Kerala-Konkan Basin, southwest continental margin of India, using multi-channel seismic and gravity modelling: Implications on India-Madagascar rifting and basin evolution
Published in Journal of Asian earth sciences (01-02-2023)“…•Moho map and stretching factors reveal extended continental crust below K-K basin.•The continent-ocean boundary is located to the west of Laccadive Ridge.•TWT…”
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5
Smurf E3 ubiquitin ligases at the cross roads of oncogenesis and tumor suppression
Published in Biochimica et biophysica acta (01-01-2013)“…Smad ubiquitin regulatory factors (Smurfs) belong to the HECT- family of E3 ubiquitin ligases and comprise mainly of two members, Smurf1 and Smurf2. Initially,…”
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meso-Tetrakis(p-sulfonatophenyl)N-Confused Porphyrin Tetrasodium Salt: A Potential Sensitizer for Photodynamic Therapy
Published in Journal of medicinal chemistry (14-06-2012)“…A water-soluble derivative of N-confused porphyrin (NCP) was synthesized, and the photodynamic therapeutic (PDT) application was investigated by photophysical…”
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7
Drug-induced Senescence Generates Chemoresistant Stemlike Cells with Low Reactive Oxygen Species
Published in The Journal of biological chemistry (28-10-2011)“…Tumor recurrence after chemotherapy or radiation remains a major obstacle to successful cancer treatment. A subset of cancer cells, termed cancer stem cells,…”
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8
Evidence for off-ridge thermal interaction along the Carlsberg and Central Indian ridges and its tectonic significance
Published in Marine geophysical researches (01-09-2024)“…Seafloor spreading along the Carlsberg and Central Indian ridges has steered the tectonic evolution of the western Indian Ocean. These spreading ridges display…”
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India‐Elan Bank‐East Antarctica Breakup, Crustal Architecture, and Margin Evolution: Results From Constrained Potential Field and Process‐Oriented Gravity Modeling of Conjugate Margin Segments
Published in Tectonics (Washington, D.C.) (01-02-2021)“…We present here the results of a seismically well‐constrained potential field modeling along with process‐oriented gravity modeling across the Eastern…”
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Coordinated dysregulation of cancer progression by the HER family and p21-activated kinases
Published in Cancer and metastasis reviews (01-09-2020)“…Most epithelial cancer types are polygenic in nature and are driven by coordinated dysregulation of multiple regulatory pathways, genes, and protein…”
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TALEN based HPV-E7 editing triggers necrotic cell death in cervical cancer cells
Published in Scientific reports (14-07-2017)“…Human Papillomavirus E7 and E6 oncoproteins have been considered as suitable candidate anti-viral targets since they cause malignant conversion in cervical…”
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MTA1 Promotes STAT3 Transcription and Pulmonary Metastasis in Breast Cancer
Published in Cancer research (Chicago, Ill.) (15-06-2013)“…Overexpression of the prometastatic chromatin modifier protein metastasis tumor antigen 1 (MTA1) in human cancer contributes to tumor aggressiveness, but the…”
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Thin oceanic crust below Bay of Bengal inferred from 3-D gravity interpretation
Published in Tectonophysics (08-10-2010)“…The Bay of Bengal (BOB) lithosphere evolved due to rifting between India and Antarctica and subsequent seafloor spreading process since the early Cretaceous is…”
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Implications of miR cluster 143/145 as universal anti-oncomiRs and their dysregulation during tumorigenesis
Published in Cancer cell international (29-09-2015)“…Tumorigenesis is a multistep process, de-regulated due to the imbalance of oncogenes as well as anti-oncogenes, resulting in disruption of tissue homeostasis…”
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Transitional dynamics of cancer stem cells in invasion and metastasis
Published in Translational oncology (01-01-2021)“…•The cell-of-origin of early and late disseminating, metastatic clones determines tumor aggressiveness.•Cellular senescence and microenvironmental cues also…”
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A novel mouse model of polytrauma with spinal cord injury–associated heterotopic ossification
Published in European cells & materials (01-01-2024)“…Heterotopic ossification (HO) refers to abnormal bone formation in soft tissues, which is a common complication of traumatic spinal cord injury (SCI). Current…”
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Synthesis and characterization of hydrothermally derived cerium-doped TiO2@MoS2 nanocomposites for waste-water treatment and super capacitor applications
Published in Bulletin of materials science (14-02-2024)“…Present research is giving attention to fabricate heterojunction nanocomposite structures. In this current study, Ce 3+ -doped TiO 2 @MoS 2 nanocomposites were…”
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Impact of HPV vaccination on HPV-related oral infections
Published in Oral oncology (01-01-2023)“…•Lower HPV16/18 prevalence among women recipients of two or three HPV vaccine doses.•One HPV vaccine dose may be less efficient in preventing oral HPV…”
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Antitumor action of curcumin in human papillomavirus associated cells involves downregulation of viral oncogenes, prevention of NFkB and AP-1 translocation, and modulation of apoptosis
Published in Molecular carcinogenesis (01-05-2006)“…Curcumin (diferuloyl methane), the major yellow pigment from the rhizomes of turmeric (Curcuma longa Linn), has anticancer properties. Infection with high‐risk…”
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A Randomized Double-Blind Placebo-Controlled Phase IIB Trial of Curcumin in Oral Leukoplakia
Published in Cancer prevention research (Philadelphia, Pa.) (01-08-2016)“…Oral leukoplakia is a potentially malignant lesion of the oral cavity, for which no effective treatment is available. We investigated the effectiveness of…”
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