Search Results - "Rademaker, Carin M. A"

Effects of Hypothermia on Pharmacokinetics and Pharmacodynamics: A Systematic Review of Preclinical and Clinical Studies by van den Broek, Marcel P. H., Groenendaal, Floris, Egberts, Antoine C. G., Rademaker, Carin M. A.

“…Examples of clinical applications of therapeutic hypothermia in modern clinical medicine include traumatic cardiac arrest, ischaemic stroke and, more recently,…”
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Neuroprotection by argon ventilation after perinatal asphyxia: a safety study in newborn piglets by Alderliesten, Thomas, Favie, Laurent M A, Neijzen, Robert W, Auwärter, Volker, Nijboer, Cora H A, Marges, Roland E J, Rademaker, Carin M A, Kempf, Jürgen, van Bel, Frank, Groenendaal, Floris

“…Hypothermia is ineffective in 45% of neonates with hypoxic-ischemic encephalopathy. Xenon has additive neuroprotective properties, but is expensive, and its…”
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Oral medicines for children in the European paediatric investigation plans by van Riet-Nales, Diana A, Römkens, Erwin G A W, Saint-Raymond, Agnes, Kozarewicz, Piotr, Schobben, Alfred F A M, Egberts, Toine C G, Rademaker, Carin M A

“…Pharmaceutical industry is no longer allowed to develop new medicines for use in adults only, as the 2007 Paediatric Regulation requires children to be…”
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Pediatric drug formulations: a review of challenges and progress by Ivanovska, Verica, Rademaker, Carin M A, van Dijk, Liset, Mantel-Teeuwisse, Aukje K

“…Children differ from adults in many aspects of pharmacotherapy, including capabilities for drug administration, medicine-related toxicity, and taste…”
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Impact of computerized physician order entry (CPOE) on PICU prescribing errors by Maat, Barbara, Bollen, Casper W., van Vught, Adrianus J., Egberts, Toine C. G., Rademaker, Carin M. A.

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Variation in antibiotic use in neonatal intensive care units in the Netherlands by Liem, T. B. Yves, Krediet, Tannette G., Fleer, André, Egberts, Toine C. G., Rademaker, Carin M. A.

“…Objectives To examine the variation in quantity and classes of antibiotics used in all 10 tertiary care neonatal intensive care units (NICUs) in the…”
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The availability and age‐appropriateness of medicines authorized for children in the Netherlands by van Riet‐Nales, Diana A., de Jager, Karin E., Schobben, Alfred F.A.M., Egberts, Toine C.G., Rademaker, Carin M.A.

“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Children are entitled to safe, efficacious, child and parent friendly (i.e. age‐appropriate) medicines. However,…”
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Correction: Neuroprotection by Argon Ventilation after Perinatal Asphyxia: A Safety Study in Newborn Piglets by Alderliesten, Thomas, Favie, Laurent M A, Neijzen, Robert W, Auwärter, Volker, Nijboer, Cora H A, Marges, Roland E J, Rademaker, Carin M A, Kempf, Jürgen, van Bel, Frank, Groenendaal, Floris

“…[This corrects the article DOI: 10.1371/journal.pone.0113575.]…”
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The Effect of Computerized Physician Order Entry on Medication Prescription Errors and Clinical Outcome in Pediatric and Intensive Care: A Systematic Review by van Rosse, Floor, Maat, Barbara, Rademaker, Carin M. A, van Vught, Adrianus J, Egberts, Antoine C. G, Bollen, Casper W

“…Pediatric and intensive care patients are particularly at risk for medication errors. Computerized physician order entry systems could be effective in reducing…”
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High prevalence of methotrexate intolerance in juvenile idiopathic arthritis: Development and validation of a methotrexate intolerance severity score by Bulatović, Maja, Heijstek, Marloes W., Verkaaik, Marleen, van Dijkhuizen, E. H. Pieter, Armbrust, Wineke, Hoppenreijs, Esther P. A., Kamphuis, Sylvia, Kuis, Wietse, Egberts, Toine C. G., Sinnema, Gerben, Rademaker, Carin M. A., Wulffraat, Nico M.

“…Objective To design and validate a new questionnaire for identifying patients with methotrexate (MTX) intolerance, and to determine the prevalence of MTX…”
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Guidelines on paediatric dosing on the basis of developmental physiology and pharmacokinetic considerations by BARTELINK, Imke H, RADEMAKER, Carin M. A, SCHOBBEN, Alfred F. A. M, VAN DEN ANKER, John N

“…The approach to paediatric drug dosing needs to be based on the physiological characteristics of the child and the pharmacokinetic parameters of the drug. This…”
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Pharmacokinetics and short-term safety of the selective NOS inhibitor 2-iminobiotin in asphyxiated neonates treated with therapeutic hypothermia by Favié, Laurent M. A., Peeters-Scholte, Cacha M. P. C. D., Bakker, Anouk, Tjabbes, Huibert, Egberts, Toine C. G., van Bel, Frank, Rademaker, Carin M. A., Vis, Peter, Groenendaal, Floris

“…Background Neonatal encephalopathy following perinatal asphyxia is a leading cause for neonatal death and disability, despite treatment with therapeutic…”
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Pharmacokinetics of morphine in encephalopathic neonates treated with therapeutic hypothermia by Favié, Laurent M A, Groenendaal, Floris, van den Broek, Marcel P H, Rademaker, Carin M A, de Haan, Timo R, van Straaten, Henrica L M, Dijk, Peter H, van Heijst, Arno, Dudink, Jeroen, Dijkman, Koen P, Rijken, Monique, Zonnenberg, Inge A, Cools, Filip, Zecic, Alexandra, van der Lee, Johanna H, Nuytemans, Debbie H G M, van Bel, Frank, Egberts, Toine C G, Huitema, Alwin D R

“…Morphine is a commonly used drug in encephalopathic neonates treated with therapeutic hypothermia after perinatal asphyxia. Pharmacokinetics and optimal dosing…”
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Pharmacokinetics and pharmacodynamics of medication in asphyxiated newborns during controlled hypothermia. The PharmaCool multicenter study by de Haan, Timo R, Bijleveld, Yuma A, van der Lee, Johanna H, Groenendaal, Floris, van den Broek, Marcel P H, Rademaker, Carin M A, van Straaten, Henrica L M, van Weissenbruch, Mirjam M, Vermeulen, Jeroen R, Dijk, Peter H, Dudink, Jeroen, Rijken, Monique, van Heijst, Arno, Dijkman, Koen P, Gavilanes, Danilo, van Kaam, Anton H, Offringa, Martin, Mathôt, Ron A A

“…In the Netherlands, perinatal asphyxia (severe perinatal oxygen shortage) necessitating newborn resuscitation occurs in at least 200 of the 180-185.000 newly…”
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Translation from animal to clinical studies, choosing the optimal moment by Favié, Laurent M. A., Peeters-Scholte, Cacha M. P. C. D., Bakker, Anouk, Tjabbes, Huibert, Egberts, Toine C. G., van Bel, Frank, Rademaker, Carin M. A., Vis, Peter, Groenendaal, Floris

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Nitric Oxide Synthase Inhibition as a Neuroprotective Strategy Following Hypoxic-Ischemic Encephalopathy: Evidence From Animal Studies by Favié, Laurent M A, Cox, Arlette R, van den Hoogen, Agnes, Nijboer, Cora H A, Peeters-Scholte, Cacha M P C D, van Bel, Frank, Egberts, Toine C G, Rademaker, Carin M A, Groenendaal, Floris

“…Hypoxic-ischemic encephalopathy following perinatal asphyxia is a leading cause of neonatal death and disability worldwide. Treatment with therapeutic…”
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Maternal Allopurinol During Fetal Hypoxia Lowers Cord Blood Levels of the Brain Injury Marker S-100B by Torrance, Helen L, Benders, Manon J, Derks, Jan B, Rademaker, Carin M. A, Bos, Arie F, Van Den Berg, Paul, Longini, Mariangela, Buonocore, Giuseppe, Venegas, MariaElena, Baquero, Hernando, Visser, Gerard H. A, Van Bel, Frank

“…Fetal hypoxia is an important determinant of neonatal encephalopathy caused by birth asphyxia, in which hypoxia-induced free radical formation plays an…”
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Anticonvulsant treatment of asphyxiated newborns under hypothermia with lidocaine: efficacy, safety and dosing by van den Broek, Marcel P H, Rademaker, Carin M A, van Straaten, Henrica L M, Huitema, Alwin D R, Toet, Mona C, de Vries, Linda S, Egberts, Antoine C G, Groenendaal, Floris

“…Lidocaine is an antiarrythmicum used as an anticonvulsant for neonatal seizures, also during therapeutic hypothermia following (perinatal) asphyxia…”
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Clinical pharmacy interventions in paediatric electronic prescriptions by Maat, Barbara, Au, Yuen San, Bollen, Casper W, van Vught, Adrianus J, Egberts, Toine C G, Rademaker, Carin M A

“…Objective To examine the frequency, nature and determinants of clinical pharmacy interventions in paediatric electronic prescriptions. Design Prospective…”
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Long-term neuroprotective effects of allopurinol after moderate perinatal asphyxia: follow-up of two randomised controlled trials by Kaandorp, Joepe J, van Bel, Frank, Veen, Sylvia, Derks, Jan B, Groenendaal, Floris, Rijken, Monique, Roze, Elise, Venema, Monica M A Uniken, Rademaker, Carin M A, Bos, Arend F, Benders, Manon J N L

“…Free-radical-induced reperfusion injury has been recognised as an important cause of brain tissue damage after birth asphyxia. Allopurinol reduces the…”
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