Search Results - "Rada, Cara C."

Therapeutic blood-brain barrier modulation and stroke treatment by a bioengineered FZD4-selective WNT surrogate in mice by Ding, Jie, Lee, Sung-Jin, Vlahos, Lukas, Yuki, Kanako, Rada, Cara C., van Unen, Vincent, Vuppalapaty, Meghah, Chen, Hui, Sura, Asmiti, McCormick, Aaron K., Tomaske, Madeline, Alwahabi, Samira, Nguyen, Huy, Nowatzke, William, Kim, Lily, Kelly, Lisa, Vollrath, Douglas, Califano, Andrea, Yeh, Wen-Chen, Li, Yang, Kuo, Calvin J.

“…Derangements of the blood-brain barrier (BBB) or blood-retinal barrier (BRB) occur in disorders ranging from stroke, cancer, diabetic retinopathy, and…”
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A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling by Grimsey, Neil J., Narala, Rachan, Rada, Cara C., Mehta, Sohum, Stephens, Bryan S., Kufareva, Irina, Lapek, John, Gonzalez, David J., Handel, Tracy M., Zhang, Jin, Trejo, JoAnn

“…Ubiquitination is essential for protein degradation and signaling and pivotal to many physiological processes. Ubiquitination of a subset of G-protein-coupled…”
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Altered contribution of RhoA/Rho kinase signaling in contractile activity of myometrium in leptin receptor-deficient mice by Harrod, Jeremy S, Rada, Cara C, Pierce, Stephanie L, England, Sarah K, Lamping, Kathryn G

“…In late gestation, enhanced myometrial contractility is mediated in part through increased Rho/Rho kinase. Since leptin, which is elevated in pregnancy and…”
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G protein–coupled receptors activate p38 MAPK via a non-canonical TAB1–TAB2– and TAB1–TAB3–dependent pathway in endothelial cells by Grimsey, Neil J., Lin, Ying, Narala, Rachan, Rada, Cara C., Mejia-Pena, Hilda, Trejo, JoAnn

“…Endothelial dysfunction is induced by inflammatory mediators including multiple G protein–coupled receptor (GPCR) agonists. However, the GPCR signaling…”
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Heat shock protein 27 activity is linked to endothelial barrier recovery after proinflammatory GPCR-induced disruption by Rada, Cara C, Mejia-Pena, Hilda, Grimsey, Neil J, Canto Cordova, Isabel, Olson, Joshua, Wozniak, Jacob M, Gonzalez, David J, Nizet, Victor, Trejo, JoAnn

“…Vascular inflammation causes endothelial barrier disruption and tissue edema. Several inflammatory mediators act through G protein–coupled receptors (GPCRs),…”
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The SK3 channel promotes placental vascularization by enhancing secretion of angiogenic factors by Rada, Cara C, Murray, Grace, England, Sarah K

“…Proper placental perfusion is essential for fetal exchange of oxygen, nutrients, and waste with the maternal circulation. Impairment of uteroplacental vascular…”
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Intrauterine telemetry to measure mouse contractile pressure in vivo by Rada, Cara C, Pierce, Stephanie L, Grotegut, Chad A, England, Sarah K

“…A complex integration of molecular and electrical signals is needed to transform a quiescent uterus into a contractile organ at the end of pregnancy. Despite…”
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Overexpression of the SK3 channel alters vascular remodeling during pregnancy, leading to fetal demise by Rada, Cara C, Pierce, Stephanie L, Nuno, Daniel W, Zimmerman, Kathy, Lamping, Kathryn G, Bowdler, Noelle C, Weiss, Robert M, England, Sarah K

“…The maternal cardiovascular system undergoes hemodynamic changes during pregnancy via angiogenesis and vasodilation to ensure adequate perfusion of the…”
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Endosomal GPCR signaling: Tyrosine Phosphorylation of a Peptide Linker in NEDD4‐2 Increases Ligase Activity to Promote p38 Proinflammatory Signaling by Grimsey, Neil J., Rada, Cara C., Narala, Rachan, Stephens, Bryan S., Mehta, Sohum J., Lapek, John J., Handel, Tracy M., Zhang, Jin J., Gonzalez, David J., Trejo, JoAnn

“…The regulation of G protein‐coupled receptor (GPCR) signaling is essential for vascular homeostasis and inflammatory responses during disease and injury. MAPK…”
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Therapeutic blood-brain barrier modulation and stroke treatment by a bioengineered FZD 4 -selective WNT surrogate in mice by Ding, Jie, Lee, Sung-Jin, Vlahos, Lukas, Yuki, Kanako, Rada, Cara C, van Unen, Vincent, Vuppalapaty, Meghah, Chen, Hui, Sura, Asmiti, McCormick, Aaron K, Tomaske, Madeline, Alwahabi, Samira, Nguyen, Huy, Nowatzke, William, Kim, Lily, Kelly, Lisa, Vollrath, Douglas, Califano, Andrea, Yeh, Wen-Chen, Li, Yang, Kuo, Calvin J

“…Derangements of the blood-brain barrier (BBB) or blood-retinal barrier (BRB) occur in disorders ranging from stroke, cancer, diabetic retinopathy, and…”
Get full text

Intrauterine Telemetry to Measure Mouse Contractile Pressure In Vivo by Rada, Cara C., Pierce, Stephanie L., Grotegut, Chad A., England, Sarah K.

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