Search Results - "Racine, Victor"
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RNAi screening reveals a large signaling network controlling the Golgi apparatus in human cells
Published in Molecular systems biology (2012)“…The Golgi apparatus has many important physiological functions, including sorting of secretory cargo and biosynthesis of complex glycans. These functions…”
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Experimental and theoretical study of mitotic spindle orientation
Published in Nature (24-05-2007)“…The architecture and adhesiveness of a cell microenvironment is a critical factor for the regulation of spindle orientation in vivo. Using a combination of…”
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Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration
Published in BMC biology (11-08-2011)“…Cell migration is essential during development and in human disease progression including cancer. Most cell migration studies concentrate on known or predicted…”
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Anisotropy of cell adhesive microenvironment governs cell internal organization and orientation of polarity
Published in Proceedings of the National Academy of Sciences - PNAS (26-12-2006)“…Control of the establishment of cell polarity is an essential function in tissue morphogenesis and renewal that depends on spatial cues provided by the…”
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Activity-Dependent Tuning of Inhibitory Neurotransmission Based on GABAAR Diffusion Dynamics
Published in Neuron (Cambridge, Mass.) (11-06-2009)“…An activity-dependent change in synaptic efficacy is a central tenet in learning, memory, and pathological states of neuronal excitability. The lateral…”
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Quantitative imaging and semiotic phenotyping of mitochondrial network morphology in live human cells
Published in PloS one (28-03-2024)“…The importance of mitochondria in tissue homeostasis, stress responses and human diseases, combined to their ability to transition between various structural…”
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Organoids: Unveiling Insights with Volume Electron Microscopy
Published in BIO web of conferences (2024)Get full text
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Surface trafficking of neurotransmitter receptor: comparison between single-molecule/quantum dot strategies
Published in The Journal of neuroscience (14-11-2007)“…Toolbox article: no abstract…”
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A cell-based small molecule screening method for identifying inhibitors of epithelial-mesenchymal transition in carcinoma
Published in PloS one (14-03-2012)“…Epithelial Mesenchymal Transition (EMT) is a crucial mechanism for carcinoma progression, as it provides routes for in situ carcinoma cells to dissociate and…”
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Mitochondrial morphology is associated with respiratory chain uncoupling in autism spectrum disorder
Published in Translational psychiatry (13-10-2021)“…Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is associated with unique changes in mitochondrial metabolism, including elevated…”
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Synaptic Control of Secretory Trafficking in Dendrites
Published in Cell reports (Cambridge) (26-06-2014)“…Localized signaling in neuronal dendrites requires tight spatial control of membrane composition. Upon initial synthesis, nascent secretory cargo in dendrites…”
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The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions
Published in The EMBO journal (04-04-2007)“…We previously demonstrated that a fraction of the human Nup107–160 nuclear pore subcomplex is recruited to kinetochores at the onset of mitosis. However, the…”
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Ankyrin G restricts ion channel diffusion at the axonal initial segment before the establishment of the diffusion barrier
Published in The Journal of cell biology (18-10-2010)“…In mammalian neurons, the precise accumulation of sodium channels at the axonal initial segment (AIS) ensures action potential initiation. This accumulation…”
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Drosophila Exocyst Components Sec5, Sec6, and Sec15 Regulate DE-Cadherin Trafficking from Recycling Endosomes to the Plasma Membrane
Published in Developmental cell (01-09-2005)“…The E-Cadherin-catenin complex plays a critical role in epithelial cell-cell adhesion, polarization, and morphogenesis. Here, we have analyzed the mechanism of…”
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Quantitative assessment of mitochondrial morphology relevant for studies on cellular health and environmental toxicity
Published in Computational and structural biotechnology journal (01-01-2023)“…Mitochondria are essential organelles that play crucial roles in cellular energy metabolism, calcium signaling and apoptosis. Their importance in tissue…”
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Automatic deep learning method for third lumbar selection and body composition evaluation on CT scans of cancer patients
Published in Frontiers in nuclear medicine (2023)“…The importance of body composition and sarcopenia is well-recognized in cancer patient outcomes and treatment tolerance, yet routine evaluations are rare due…”
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Visualization and quantification of vesicle trafficking on a three‐dimensional cytoskeleton network in living cells
Published in Journal of microscopy (Oxford) (01-03-2007)“…Summary Recent progress in biology and microscopy has made it possible to acquire multidimensional data on rapid cellular activities. Unfortunately, the data…”
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Ectodermal influx and cell hypertrophy provide early growth for all murine mammary rudiments, and are differentially regulated among them by Gli3
Published in PloS one (27-10-2011)“…Mammary gland development starts in utero with one or several pairs of mammary rudiments (MRs) budding from the surface ectodermal component of the mammalian…”
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Myosin Va Mediates Docking of Secretory Granules at the Plasma Membrane
Published in The Journal of neuroscience (26-09-2007)“…Myosin Va (MyoVa) is a prime candidate for controlling actin-based organelle motion in neurons and neuroendocrine cells. Its function in secretory granule (SG)…”
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