Search Results - "Rachubinski, R A"

Dynamics of peroxisome assembly and function by Titorenko, Vladimir I, Rachubinski, Richard A

“…Recent studies in human cells and in the yeast Yarrowia lipolytica have shown that peroxisomes consist of numerous structurally distinct subcompartments that…”
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Identification of a Peroxisome Proliferator-Responsive Element Upstream of the Gene Encoding Rat Peroxisomal Enoyl-CoA Hydratase/3-Hydroxyacyl-CoA Dehydrogenase by Zhang, Baowei, Marcus, Sandra L., Sajjadi, Fereydoun G., Alvares, Keith, Reddy, Janardan K., Subramani, Suresh, Rachubinski, Richard A., Capone, John P.

“…Ciprofibrate, a hypolipidemic drug that acts as a peroxisome proliferator, induces the transcription of genes encoding peroxisomal β-oxidation enzymes. To…”
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Mutagenesis of the amino targeting signal of Saccharomyces cerevisiae 3-ketoacyl-CoA thiolase reveals conserved amino acids required for import into peroxisomes in vivo by Glover, J.R, Andrews, D.W, Subramani, S, Rachubinski, R.A

“…Saccharomyces cerevisiae peroxisomal 3-ketoacyl-CoA thiolase is a soluble matrix protein that does not end in a consensus peroxisomal targeting signal-1. The…”
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Saccharomyces cerevisiae peroxisomal thiolase is imported as a dimer by Glover, J.R. (McMaster University, Ontario, Canada), Andrews, D.W, Rachubinski, R.A

“…The active conformation of native peroxisomal 3-ketoacyl-CoA thiolases (EC 2.3.1.16) is homodimeric. We have previously shown that a truncated Saccharomyces…”
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The endoplasmic reticulum plays an essential role in peroxisome biogenesis by Titorenko, Vladimir I, Rachubinski, Richard A

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Pex16p homolog SSE1 and storage organelle formation in Arabidopsis seeds by Lin, Y, Nguyen, L.V, Rachubinski, R.A, Goodman, H.M

“…Mature Arabidopsis seeds are enriched in storage proteins and lipids, but lack starch. In the shrunken seed 1 (sse1) mutant, however, starch is favored over…”
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Diverse Peroxisome Proliferator-Activated Receptors Bind to the Peroxisome Proliferator-Responsive Elements of the Rat Hydratase/Dehydrogenase and Fatty Acyl-CoA Oxidase Genes but Differentially Induce Expression by Marcus, Sandra L., Miyata, Kenji S., Zhang, Baowei, Subramani, Suresh, Rachubinski, Richard A., Capone, John P.

“…The ability of peroxisome proliferator-activated receptors (PPARs) to induce expression of a reporter gene linked to a peroxisome proliferator-responsive…”
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Involvement of 70-kD Heat-Shock Proteins in Peroxisomal Import by Walton, Paul A., Wendland, Martin, Subramani, Suresh, Rachubinski, Richard A., Welch, William J.

“…This report describes the involvement of 70-kD heat-shock proteins (hsp70) in the import of proteins into mammalian peroxisomes. Employing a…”
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Four distinct secretory pathways serve protein secretion, cell surface growth, and peroxisome biogenesis in the yeast Yarrowia lipolytica by Titorenko, Vladimir I., Ogrydziak, David M., Rachubinski, Richard A.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Endosomal proteolysis of insulin by an acidic thiol metalloprotease unrelated to insulin degrading enzyme by AUTHIER, F, RACHUBINSKI, R. A, POSNER, B. I, BERGERON, J. J. M

“…Although insulin is degraded as a consequence of receptor-mediated endocytosis, the location and nature of the responsible proteinase(s) remain controversial…”
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Chicken ovalbumin upstream promoter transcription factor (COUP-TF) binds to a peroxisome proliferator-responsive element and antagonizes peroxisome proliferator-mediated signaling by MIYATA, K. S, BAOWEI ZHANG, MARCUS, S. L, CAPONE, J. P, RACHUBINSKI, R. A

“…Peroxisome proliferators form a family of diverse xenobiotic compounds that includes hypolipidemic agents, herbicides, and plasticizers. These compounds…”
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Pay32p of the yeast Yarrowia lipolytica is an intraperoxisomal component of the matrix protein translocation machinery by Szilard, R.K. (University of Alberta, Edmonton, Canada.), Titorenko, V.I, Veenhuis, M, Rachubinski, R.A

“…Pay mutants of the yeast Yarrowia lipolytica fail to assemble functional peroxisomes. One mutant strain, pay32-1, has abnormally small peroxisomes that are…”
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The carboxyl-terminal tripeptide Ala-Lys-Ile is essential for targeting Candida tropicalis trifunctional enzyme to yeast peroxisomes by AITCHISON, J. D, WAYNE MURRAY, W, RACHUBINSKI, R. A

“…The gene encoding Candida tropicalis peroxisomal trifunctional enzyme, hydratase-dehydrogenase-epimerase (HDE), was expressed in both Candida albicans and…”
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Characterization of protein-DNA interactions within the peroxisome proliferator-responsive element of the rat hydratase-dehydrogenase gene by BAOWEI ZHANG, MARCUS, S. L, MIYATA, K. S, SURESH SUBRAMANI, CAPONE, J. P, RACHUBINSKI, R. A

“…A peroxisome proliferator-responsive element is located in the 5'-flanking region of the gene encoding rat hydratase-dehydrogenase, the second enzyme of the…”
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Lack of Peroxisomal Catalase Causes a Progeric Phenotype in Caenorhabditis elegans by Petriv, Oleh I, Rachubinski, Richard A

“…Studies using the nematode Caenorhabditis elegans as a model system to investigate the aging process have implicated the insulin/insulin-like growth factor-I…”
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The life cycle of the peroxisome by Titorenko, Vladimir I, Rachubinski, Richard A

“…Peroxisomes are highly adaptable organelles that carry out oxidative reactions. Distinct cellular machineries act together to coordinate peroxisome formation,…”
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Degradation of the Cleaved Leader Peptide of Thiolase by a Peroxisomal Proteinase by Authier, François, John J. M. Bergeron, Ou, Wei-Jia, Rachubinski, Richard A., Posner, Barry I., Walton, Paul A.

“…A peroxisomal location for insulin-degrading enzyme (IDE) has been defined by confocal immunofluorescence microscopy of stably transfected CHO cells…”
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Synthesis of a Major Integral Membrane Polypeptide of Rat Liver Peroxisomes on Free Polysomes by Fujiki, Yukio, Rachubinski, Richard A., Lazarow, Paul B.

“…The manner of synthesis and assembly of the peroxisomal membrane proteins is unknown. Understanding these processes is essential to an understanding of the…”
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Inp1p is a peroxisomal membrane protein required for peroxisome inheritance in Saccharomyces cerevisiae by Fagarasanu, Monica, Fagarasanu, Andrei, Tam, Yuen Yi C, Aitchison, John D, Rachubinski, Richard A

“…Cells have evolved molecular mechanisms for the efficient transmission of organelles during cell division. Little is known about how peroxisomes are inherited…”
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A new definition for the consensus sequence of the peroxisome targeting signal type 2 by Petriv, Oleh I, Tang, Ling, Titorenko, Vladimir I, Rachubinski, Richard A

“…All organisms except the nematode Caenorhabditis elegans have been shown to possess an import system for peroxisomal proteins containing a peroxisome targeting…”
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