Search Results - "Rachid, A"
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Cooperation Between Translating Ribosomes and RNA Polymerase in Transcription Elongation
Published in Science (American Association for the Advancement of Science) (23-04-2010)“…During transcription of protein-coding genes, bacterial RNA polymerase (RNAP) is closely followed by a ribosome that translates the newly synthesized…”
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Yeast RNA exosome activity is necessary for maintaining cell wall stability through proper protein glycosylation
Published in Molecular biology of the cell (01-03-2021)“…Nuclear RNA exosome is the main 3'→5' RNA degradation and processing complex in eukaryotic cells and its dysregulation therefore impacts gene expression and…”
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mRNA with Mammalian Codon Bias Accumulates in Yeast Mutants with Constitutive Stress Granules
Published in International journal of molecular sciences (12-02-2020)“…Stress granules and P bodies are cytoplasmic structures assembled in response to various stress factors and represent sites of temporary storage or decay of…”
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Regulation of the conserved 3′‐5′ exoribonuclease EXOSC10/Rrp6 during cell division, development and cancer
Published in Biological reviews of the Cambridge Philosophical Society (01-08-2021)“…ABSTRACT The conserved 3′‐5′ exoribonuclease EXOSC10/Rrp6 processes and degrades RNA, regulates gene expression and participates in DNA double‐strand break…”
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5
Skin wound healing is accelerated and scarless in the absence of commensal microbiota
Published in The Journal of immunology (1950) (15-11-2014)“…The commensal microbiota has a high impact on health and disease by modulating the development and homeostasis of host immune system. Immune cells are involved…”
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Complement C5 activation during influenza A infection in mice contributes to neutrophil recruitment and lung injury
Published in PloS one (16-05-2013)“…Influenza virus A (IAV) causes annual epidemics and intermittent pandemics that affect millions of people worldwide. Potent inflammatory responses are commonly…”
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Deciphering the Dynamic Landscape of Transcription-Associated mRNP Quality Control Components Over the Whole Yeast Genome
Published in Methods in molecular biology (Clifton, N.J.) (2021)“…In eukaryotic cells, aberrant mRNPs with processing and packaging defects are targeted co-transcriptionally by a surveillance system that triggers their…”
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Tho2 is critical for the recruitment of Rrp6 to chromatin in response to perturbed mRNP biogenesis
Published in RNA (Cambridge) (01-01-2024)“…The eukaryotic THO complex coordinates the assembly of so-called messenger RNA-ribonucleoprotein particles (mRNPs), a process that involves cotranscriptional…”
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Management of fuel cell power and supercapacitor state-of-charge for electric vehicles
Published in Electric power systems research (01-07-2018)“…•The system is modeled and controlled without cancelling nonlinearities.•Load power is well satisfied while respecting fuel cell rated power.•Fuel cell current…”
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In situ footprinting of E. coli transcription elongation complex with chloroacetaldehyde
Published in Methods in molecular biology (Clifton, N.J.) (2015)“…The structure and dynamics of Escherichia coli transcription elongation complex are now well documented. However, most of the studies have been conducted in…”
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Numerical approximation of a generalized time fractional partial integro-differential equation of Volterra type based on a meshless method
Published in Partial differential equations in applied mathematics : a spin-off of Applied Mathematics Letters (01-09-2024)“…The moving least squares (MLS) approximation is used in this study to solve time-fractional partial integro-differential equations (TFPIDE). In our approach,…”
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DIET AND ISCHEMIC BURDEN: A COMPARATIVE ANALYSIS OF A PLANT BASED REGIMEN VERSUS A MEDITERRANEAN REGIMEN IN PATIENTS WITH CORONARY ARTERY DISEASE
Published in Journal of the American College of Cardiology (21-03-2017)“…Background: The cardio protective effects of various diet regimens in primary prevention have been studied and elucidated in registry data and more recently in…”
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Cotranscriptional Recruitment of RNA Exosome Cofactors Rrp47p and Mpp6p and Two Distinct Trf-Air-Mtr4 Polyadenylation (TRAMP) Complexes Assists the Exonuclease Rrp6p in the Targeting and Degradation of an Aberrant Messenger Ribonucleoprotein Particle (mRNP) in Yeast
Published in The Journal of biological chemistry (01-11-2013)“…The cotranscriptional mRNA processing and packaging reactions that lead to the formation of export-competent messenger ribonucleoprotein particles (mRNPs) are…”
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Recombinant yeast and human cells as screening tools to search for antibacterial agents targeting the transcription termination factor Rho
Published in Journal of antibiotics (01-03-2018)“…The alarming issue of antibiotic resistance expansion requires a continuous search for new and efficient antibacterial agents. Here we describe the design of…”
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Perturbation of mRNP biogenesis reveals a dynamic landscape of the Rrp6-dependent surveillance machinery trafficking along the yeast genome
Published in RNA biology (03-07-2019)“…Eukaryotic cells have evolved a nuclear quality control (QC) system to monitor the co-transcriptional mRNA processing and packaging reactions that lead to the…”
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The Aryl Hydrocarbon Receptor Modulates Production of Cytokines and Reactive Oxygen Species and Development of Myocarditis during Trypanosoma cruzi Infection
Published in Infection and immunity (01-10-2016)“…The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor involved in controlling several aspects of immune responses, including the…”
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Nuclear mRNA quality control in yeast is mediated by Nrd1 co-transcriptional recruitment, as revealed by the targeting of Rho-induced aberrant transcripts
Published in Nucleic acids research (01-04-2011)“…The production of mature export-competent transcripts is under the surveillance of quality control steps where aberrant mRNP molecules resulting from…”
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18
A mathematical model for pantograph-catenary interaction
Published in Mathematical and computer modelling of dynamical systems (02-09-2016)“…Modelling the interaction between the pantograph and the catenary is an active field due to the development of high-speed trains. In this article, a 3D…”
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Protocol for efficient fluorescence 3′ end-labeling of native noncoding RNA domains
Published in MethodsX (01-01-2020)“…Noncoding RNAs (ncRNAs) comprise a class of versatile transcripts that are highly involved in the regulation of a wide range of biological processes…”
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Multi-walled carbon nanotubes functionalized with recombinant Dengue virus 3 envelope proteins induce significant and specific immune responses in mice
Published in Journal of nanobiotechnology (04-04-2017)“…Dengue is the most prevalent arthropod-borne viral disease in the world. In this article we present results on the development, characterization and…”
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