Search Results - "Rachel Bender Ignacio"

Observational study of effects of HIV acquisition and antiretroviral treatment on biomarkers of systemic immune activation by Kosmider, Ewelina, Wallner, Jackson, Gervassi, Ana, Bender Ignacio, Rachel A, Pinto-Santini, Delia, Gornalusse, German, Pandey, Urvashi, Hladik, Florian, Edlefsen, Paul T, Lama, Javier R, Duerr, Ann C, Frenkel, Lisa M

“…To assess whether biomarkers of systemic inflammation are associated with HIV acquisition or with the timing of ART initiation ("immediate", at diagnosis,…”
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Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses by White, Judith M, Schiffer, Joshua T, Bender Ignacio, Rachel A, Xu, Shuang, Kainov, Denis, Ianevski, Aleksandr, Aittokallio, Tero, Frieman, Matthew, Olinger, Gene G, Polyak, Stephen J

“…The world was unprepared for coronavirus disease 2019 (COVID-19) and remains ill-equipped for future pandemics. While unprecedented strides have been made…”
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Factors Associated With Severity of COVID-19 Disease in a Multicenter Cohort of People With HIV in the United States, March–December 2020 by Shapiro, Adrienne E., Bender Ignacio, Rachel A., Whitney, Bridget M., Delaney, Joseph A., Nance, Robin M., Bamford, Laura, Wooten, Darcy, Keruly, Jeanne C., Burkholder, Greer, Napravnik, Sonia, Mayer, Kenneth H., Webel, Allison R., Kim, H. Nina, Van Rompaey, Stephen E., Christopoulos, Katerina, Jacobson, Jeffrey, Karris, Maile, Smith, Davey, Johnson, Mallory O., Willig, Amanda, Eron, Joseph J., Hunt, Peter, Moore, Richard D., Saag, Michael S., Mathews, W. Christopher, Crane, Heidi M., Cachay, Edward R., Kitahata, Mari M.

“…Understanding the spectrum of COVID-19 in people with HIV (PWH) is critical to provide clinical guidance and risk reduction strategies. Centers for AIDS…”
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New skin lesions in a liver transplant recipient by Blain, Michela, Walter, Kara, Sibulesky, Lena, Bender Ignacio, Rachel

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HIV Disease Dynamics and Markers of Inflammation and CNS Injury During Primary HIV Infection and Their Relationship to Cognitive Performance by Longino, August A., Paul, Robert, Wang, Yixin, Lama, Javier R., Brandes, Peter, Ruiz, Eduardo, Correa, Cecilia, Keating, Sheila, Spudich, Serena S., Pilcher, Christopher, Vecchio, Alyssa, Pasalar, Siavash, Bender Ignacio, Rachel A., Valdez, Rogelio, Dasgupta, Sayan, Robertson, Kevin, Duerr, Ann

“…Early systemic and central nervous system viral replication and inflammation may affect brain integrity in people with HIV, leading to chronic cognitive…”
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Mycobacterium tuberculosis infection, immune activation, and risk of HIV acquisition by Bender Ignacio, Rachel A, Long, Jessica, Saha, Aparajita, Nguyen, Felicia K, Joudeh, Lara, Valinetz, Ethan, Mendelsohn, Simon C, Scriba, Thomas J, Hatherill, Mark, Janes, Holly, Churchyard, Gavin, Buchbinder, Susan, Duerr, Ann, Shah, Javeed A, Hawn, Thomas R

“…Although immune activation is associated with HIV acquisition, the nature of inflammatory profiles that increase HIV risk, which may include responses to M…”
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Initiation of Antiretroviral Therapy during Primary HIV Infection: Effects on the Latent HIV Reservoir, Including on Analytic Treatment Interruptions by Shelton, Eva M, Reeves, Daniel B, Bender Ignacio, Rachel A

“…Antiretroviral therapy (ART) inhibits HIV replication but does not eradicate the latent reservoir. The previous research suggests that earlier ART initiation…”
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Statistical Challenges When Analyzing SARS-CoV-2 RNA Measurements Below the Assay Limit of Quantification in COVID-19 Clinical Trials by Moser, Carlee B, Chew, Kara W, Giganti, Mark J, Li, Jonathan Z, Aga, Evgenia, Ritz, Justin, Greninger, Alexander L, Javan, Arzhang Cyrus, Bender Ignacio, Rachel, Daar, Eric S, Wohl, David A, Currier, Judith S, Eron, Joseph J, Smith, Davey M, Hughes, Michael D

“…Abstract Most clinical trials evaluating coronavirus disease 2019 (COVID-19) therapeutics include assessments of antiviral activity. In recently completed…”
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Comparative Pharmacokinetics of Tixagevimab/Cilgavimab (AZD7442) Administered Intravenously Versus Intramuscularly in Symptomatic SARS‐CoV‐2 Infection by Bender Ignacio, Rachel A., Wohl, David A., Arends, Rosalin, Pilla Reddy, Venkatesh, Mu, Ying, Javan, Arzhang Cyrus, Hughes, Michael D., Eron, Joseph J., Currier, Judith S., Smith, Davey, Chew, Kara W., Gibbs, Michael, Fletcher, Courtney V.

“…AZD7442 (Evusheld) is a combination of two human anti‐severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2) monoclonal antibodies (mAbs), tixagevimab…”
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Impact of Antiretroviral Therapy on Cancer Treatment Outcomes among People Living with HIV in Low- and Middle-Income Countries: a Systematic Review by Montaño, Michalina A, Chagomerana, Maganizo B, Borok, Margaret, Painschab, Matthew, Uldrick, Thomas S, Bender Ignacio, Rachel A

“…Purpose of Review The relationship between antiretroviral therapy (ART) and cancer treatment outcomes among people living with HIV (PLWH) in low- and…”
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Long-term effects of early antiretroviral initiation on HIV reservoir markers: a longitudinal analysis of the MERLIN clinical study by Massanella, Marta, Bender Ignacio, Rachel A, Lama, Javier R, Pagliuzza, Amélie, Dasgupta, Sayan, Alfaro, Ricardo, Rios, Jessica, Ganoza, Carmela, Pinto-Santini, Delia, Gilada, Trupti, Duerr, Ann, Chomont, Nicolas

“…Early antiretroviral therapy (ART) initiation (ie, within 3 months of infection) limits establishment of the HIV reservoir. However, the effect of early ART…”
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Characterizing HIV status documentation among cancer patients at regional cancer centers in Malawi, Zimbabwe, and South Africa by Montaño, Michalina A, Mtisi, Takudzwa, Ndlovu, Ntokozo, Borok, Margaret, Bula, Agatha, Joffe, Maureen, Bender Ignacio, Rachel, Chagomerana, Maganizo B

“…In East and Southern Africa, people with HIV (PWH) experience worse cancer-related outcomes and are at higher risk of developing certain cancers. Siloed care…”
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Oral and Vaginal Tenofovir for Genital Herpes Simplex Virus Type 2 Shedding in Immunocompetent Women: A Double-Blind, Randomized, Cross-over Trial by Ignacio, Rachel A. Bender, Perti, Tara, Magaret, Amalia S., Rajagopal, Sharanya, Stevens, Claire E., Huang, Meei-Li, Selke, Stacy, Johnston, Christine, Marrazzo, Jeanne, Wald, Anna

“…Background. Tenofovir is a potent anti-human immunodeficiency virus (HIV) agent that decreased risk of herpes simplex virus type 2 (HSV-2) acquisition in HIV…”
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Racial and ethnic disparities in coronavirus disease 2019 disease incidence independent of comorbidities, among people with HIV in the United States by Bender Ignacio, Rachel A, Shapiro, Adrienne E, Nance, Robin M, Whitney, Bridget M, Delaney, Joseph A C, Bamford, Laura, Wooten, Darcy, Karris, Maile Y, Mathews, William C, Kim, Hyang Nina, Keruly, Jeanne, Burkholder, Greer, Napravnik, Sonia, Mayer, Kenneth H, Jacobson, Jeffrey, Saag, Michael, Moore, Richard D, Eron, Joseph J, Willig, Amanda L, Christopoulos, Katerina A, Martin, Jeffrey, Hunt, Peter W, Crane, Heidi M, Kitahata, Mari M, Cachay, Edward R

“…To define the incidence of clinically detected coronavirus disease 2019 (COVID-19) in people with HIV (PWH) in the United States and evaluate how racial and…”
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Dynamic immune markers predict HIV acquisition and augment associations with sociobehavioral factors for HIV exposure by Bender Ignacio, Rachel A., Dasgupta, Sayan, Valdez, Rogelio, Pandey, Urvashi, Pasalar, Siavash, Alfaro, Ricardo, Hladik, Florian, Gornalusse, Germán, Lama, Javier R., Duerr, Ann

“…Prior studies attempting to link biomarkers of immune activation with risk of acquiring HIV have relied on cross sectional samples, most without proximity to…”
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Comprehensive viromewide antibody responses by systematic epitope scanning after hematopoietic cell transplantation by Bender Ignacio, Rachel A., Dasgupta, Sayan, Stevens-Ayers, Terry, Kula, Tomasz, Hill, Joshua A., Lee, Stephanie J., Mielcarek, Marco, Duerr, Ann, Elledge, Stephen J., Boeckh, Michael

“…Further insight into humoral viral immunity after hematopoietic cell transplantation (HCT) could have potential impact on donor selection or monitoring of…”
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Protocol for evaluating mechanistic pathways associated with HIV acquisition via nested Least Absolute Shrinkage and Selective Operator analysis by Dasgupta, Sayan, Ulrich, Angela K., Duerr, Ann, Bender Ignacio, Rachel A.

“…Statistical analysis to evaluate mechanistic pathways can be limited by non-causal associations as well as co-linearity of high-dimensional data. Here, we…”
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Strategies for Expediting Clinical Trials in the Next Public Health Emergency by Titanji, Boghuma K., Boulware, David R., Bender Ignacio, Rachel A.

“…This Viewpoint highlights areas for improving implementation of future epidemic clinical trials, focusing on research among nonhospitalized persons…”
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Evolving Paradigms in HIV Malignancies: Review of Ongoing Clinical Trials by Bender Ignacio, Rachel A, Lin, Lilie L, Rajdev, Lakshmi, Chiao, Elizabeth

“…This review highlights current interventional clinical trials for HIV-associated malignancies (HIVAMs), with emphasis on 4 mechanistic areas: immunomodulatory…”
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A Population‐based Study of Perinatal Infection Risk in Women with and without Systemic Lupus Erythematosus and their Infants by Bender Ignacio, Rachel A., Madison, Amy T., Moshiri, Ata, Weiss, Noel S., Mueller, Beth A.

“…Background Increased risk of adverse birth outcomes is well described in women with systemic lupus erythematosus (SLE), but risk of maternal or infant…”
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