Search Results - "Raby, B."

MUC1 inhibition leads to decrease in PD-L1 levels via upregulation of miRNAs by Pyzer, A R, Stroopinsky, D, Rosenblatt, J, Anastasiadou, E, Rajabi, H, Washington, A, Tagde, A, Chu, J-H, Coll, M, Jiao, A L, Tsai, L T, Tenen, D E, Cole, L, Palmer, K, Ephraim, A, Leaf, R K, Nahas, M, Apel, A, Bar-Natan, M, Jain, S, McMasters, M, Mendez, L, Arnason, J, Raby, B A, Slack, F, Kufe, D, Avigan, D

“…The PD-L1/PD-1 pathway is a critical component of the immunosuppressive tumor microenvironment in acute myeloid leukemia (AML), but little is known about its…”
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Gene-by-environment effect of house dust mite on purinergic receptor P2Y12 (P2RY12) and lung function in children with asthma by Bunyavanich, S., Boyce, J. A., Raby, B. A., Weiss, S. T.

“…Summary Background Distinct receptors likely exist for leukotriene (LT)E4, a potent mediator of airway inflammation. Purinergic receptor P2Y12 is needed for…”
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Transactivation of vimentin by β-catenin in human breast cancer cells by GILLES, Christine, POLETTE, Myriam, MESTDAGT, Mélanie, NAWROCKI-RABY, Béatrice, RUGGERI, Philippe, BIREMBAUT, Philippe, FOIDART, Jean-Michel

“…The cytoplasmic and nuclear redistribution of beta-catenin and the de novo expression of vimentin are frequently involved in the epithelial-to-mesenchymal…”
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HLA-DQ strikes again: Genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults by Lasky-Su, J., Himes, B. E., Raby, B. A., Klanderman, B. J., Sylvia, J. Senter, Lange, C., Melen, E., Martinez, F. D., Israel, E., Gauderman, J., Gilliland, F., Sleiman, P., Hakonarson, H., Celedón, J. C., Soto-Quiros, M., Avila, L., Lima, J. J., Irvin, C. G., Peters, S. P., Boushey, H., Chinchilli, V. M., Mauger, D., Tantisira, K., Weiss, S. T.

“…Summary Background Asthma is a common chronic respiratory disease in children and adults. An important genetic component to asthma susceptibility has long been…”
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The interaction of glutathione S-transferase M1-null variants with tobacco smoke exposure and the development of childhood asthma by Rogers, A. J., Brasch-Andersen, C., Ionita-Laza, I., Murphy, A., Sharma, S., Klanderman, B. J., Raby, B. A.

“…Summary Background The glutathione S‐transferase M1 (GSTM1)‐null variant is a common copy number variant associated with adverse pulmonary outcomes, including…”
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Human airway surface epithelial regeneration is delayed and abnormal in cystic fibrosis by Hajj, R, Lesimple, P, Nawrocki-Raby, B, Birembaut, P, Puchelle, E, Coraux, C

“…Cystic fibrosis (CF) at an advanced stage of the disease is characterized by airway epithelial injury and remodelling. Whether CF remodelling is related to…”
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Phenotypical plasticity and targeted therapies in non-small cell lung carcinomas by Da Silva, J, Dalstein, V, Polette, M, Nawrocki-Raby, B

“…Lung cancer is the most diagnosed and deathly type of cancer worldwide. It has a poor prognosis because of a late diagnosis, high metastatic potential and…”
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Cystic fibrosis mutations for p.F508del compound heterozygotes predict sweat chloride levels and pancreatic sufficiency by Sebro, R, Levy, H, Schneck, K, Dimmock, D, Raby, BA, Cannon, CL, Broeckel, U, Risch, NJ

“…Sebro R, Levy H, Schneck K, Dimmock D, Raby BA, Cannon CL, Broeckel U, Risch NJ. Cystic fibrosis mutations for p.F508del compound heterozygotes predict sweat…”
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Regulation of membrane-type 1 matrix metalloproteinase expression by zonula occludens-2 in human lung cancer cells by Luczka, E., Syne, L., Nawrocki-Raby, B., Kileztky, C., Hunziker, W., Birembaut, P., Gilles, C., Polette, Myriam

“…During tumor invasion, tumor epithelial cells acquire migratory and invasive properties involving important phenotypic alterations. Among these changes, one…”
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Tumour invasion and matrix metalloproteinases by Polette, Myriam, Nawrocki-Raby, Béatrice, Gilles, Christine, Clavel, Christine, Birembaut, Philippe

“…Matrix metalloproteinases (MMPs) are proteolytic enzymes which play a major role in tumour invasion. They are mainly produced by host stromal cells in most…”
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Copy number variation prevalence in known asthma genes and their impact on asthma susceptibility by Rogers, A. J., Chu, J.-H., Darvishi, K., Ionita-Laza, I., Lehmann, H., Mills, R., Lee, C., Raby, B. A.

“…Summary Background Genetic studies have identified numerous genes reproducibly associated with asthma, yet these studies have focussed almost entirely on…”
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Genomic screening and replication using the same data set in family-based association testing by Van Steen, Kristel, McQueen, Matthew B, Herbert, Alan, Raby, Benjamin, Lyon, Helen, DeMeo, Dawn L, Murphy, Amy, Su, Jessica, Datta, Soma, Rosenow, Carsten, Christman, Michael, Silverman, Edwin K, Laird, Nan M, Weiss, Scott T, Lange, Christoph

“…The Human Genome Project and its spin-offs are making it increasingly feasible to determine the genetic basis of complex traits using genome-wide association…”
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Beta-catenin and ZO-1: shuttle molecules involved in tumor invasion-associated epithelial-mesenchymal transition processes by Polette, Myriam, Mestdagt, Mélanie, Bindels, Sandrine, Nawrocki-Raby, Béatrice, Hunziker, Walter, Foidart, Jean-Michel, Birembaut, Philippe, Gilles, Christine

“…The cytoplasmic/nuclear relocalization of beta-catenin and ZO-1 from the adherens and tight junctions are common processes of the epithelial-mesenchymal…”
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Association of VEGF polymorphisms with childhood asthma, lung function and airway responsiveness by Sharma, S, Murphy, A. J, Soto-Quiros, M. E, Avila, L, Klanderman, B. J, Sylvia, J. S, Celedon, J. C, Raby, B. A, Weiss, S. T

“…Vascular endothelial growth factor (VEGF) is an angiogenic factor implicated in asthma severity. The objective of the present study was to determine whether…”
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β-2 adrenergic receptor gene methylation is associated with decreased asthma severity in inner-city schoolchildren: asthma and rhinitis by Gaffin, J M, Raby, B A, Petty, C R, Hoffman, E B, Baccarelli, A A, Gold, D R, Phipatanakul, W

“…Genetic variation in the β-2 adrenergic receptor gene (ADRB2) has been implicated in asthma severity and control with conflicting results. Epigenetic variation…”
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Fhit regulates invasion of lung tumor cells by Joannes, A, Bonnomet, A, Bindels, S, Polette, M, Gilles, C, Burlet, H, Cutrona, J, Zahm, J-M, Birembaut, P, Nawrocki-Raby, B

“…In many types of cancers, the fragile histidine triad ( Fhit ) gene is frequently targeted by genomic alterations leading to a decrease or loss of gene and…”
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173: Role of NANOS family members in tumor progression by De Keuckelaere, E, Andries, V, Staes, K, Grelet, S, Nawrocki-Raby, B, Birembaut, P, Van Roy, F

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The E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression by Bonnomet, A, Polette, M, Strumane, K, Gilles, C, Dalstein, V, Kileztky, C, Berx, G, van Roy, F, Birembaut, P, Nawrocki-Raby, B

“…In this study, we examined the role of the E-cadherin-repressed gene human Nanos1 (hNanos1) in tumor invasion process. First, our in vivo study revealed that…”
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Toll-like receptor 6 gene ( ): single-nucleotide polymorphism frequencies and preliminary association with the diagnosis of asthma by Tantisira, K, Klimecki, W T, Lazarus, R, Palmer, L J, Raby, B A, Kwiatkowski, D J, Silverman, E, Vercelli, D, Martinez, F D, Weiss, S T

“…Toll-like receptor 6 (TLR6) is one of a series of highly conserved innate immune receptors. We resequenced TLR6 in DNA samples from 24 African Americans, 23…”
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Membrane-type 1 matrix metalloproteinase expression is regulated by zonula occludens-1 in human breast cancer cells by POLETTE, Myriam, GILLES, Christine, NAWROCKI-RABY, Béatrice, LOHI, Jouko, HUNZIKER, Walter, FOIDART, Jean-Michel, BIREMBAUT, Philippe

“…The acquisition of a migratory/invasive phenotype by tumor cells is characterized by the loss of cell-cell adhesion contacts and the expression of degradative…”
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