Search Results - "Rabold, Katrin"

Eight-Color Multiplex Immunohistochemistry for Simultaneous Detection of Multiple Immune Checkpoint Molecules within the Tumor Microenvironment by Gorris, Mark A J, Halilovic, Altuna, Rabold, Katrin, van Duffelen, Anne, Wickramasinghe, Iresha N, Verweij, Dagmar, Wortel, Inge M N, Textor, Johannes C, de Vries, I Jolanda M, Figdor, Carl G

“…Therapies targeting immune checkpoint molecules CTLA-4 and PD-1/PD-L1 have advanced the field of cancer immunotherapy. New mAbs targeting different immune…”
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The clinical application of cancer immunotherapy based on naturally circulating dendritic cells by Bol, Kalijn F, Schreibelt, Gerty, Rabold, Katrin, Wculek, Stefanie K, Schwarze, Julia Katharina, Dzionek, Andrzej, Teijeira, Alvaro, Kandalaft, Lana E, Romero, Pedro, Coukos, George, Neyns, Bart, Sancho, David, Melero, Ignacio, de Vries, I Jolanda M

“…Dendritic cells (DCs) can initiate and direct adaptive immune responses. This ability is exploitable in DC vaccination strategies, in which DCs are educated ex…”
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Effect of PTEN inactivating germline mutations on innate immune cell function and thyroid cancer-induced macrophages in patients with PTEN hamartoma tumor syndrome by Sloot, Yvette J. E., Rabold, Katrin, Netea, Mihai G., Smit, Johannes W. A., Hoogerbrugge, Nicoline, Netea-Maier, Romana T.

“…PTEN hamartoma tumor syndrome (PHTS) is caused by inactivating germline PTEN mutations with subsequent activation of Akt-mTOR signaling, leading to an…”
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Enhanced lipid biosynthesis in human tumor-induced macrophages contributes to their protumoral characteristics by Rabold, Katrin, Aschenbrenner, Anna, Thiele, Christoph, Boahen, Collins K, Schiltmans, Alexander, Smit, Johannes W A, Schultze, Joachim L, Netea, Mihai G, Adema, Gosse J, Netea-Maier, Romana T

“…BackgroundTumor-associated macrophages (TAMs) are key components of the tumor microenvironment (TME) in non-medullary thyroid carcinoma (TC) and neuroblastoma…”
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Influence of Lenvatinib on the Functional Reprogramming of Peripheral Myeloid Cells in the Context of Non-Medullary Thyroid Carcinoma by Peng, Chunying, Rabold, Katrin, Netea, Mihai G, Jaeger, Martin, Netea-Maier, Romana T

“…Lenvatinib is a multitarget tyrosine kinase inhibitor (TKI) approved for the treatment of several types of cancers, including metastatic differentiated thyroid…”
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BRAF V600E Inhibitor Radiosensitizes Thyroid Cancer-Letter by Göttgens, Eva-Leonne, Rabold, Katrin, Span, Paul N

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Cellular metabolism of tumor‐associated macrophages – functional impact and consequences by Rabold, Katrin, Netea, Mihai G., Adema, Gosse J., Netea‐Maier, Romana T.

“…Macrophages are innate immune cells that play a role not only in host defense against infections, but also in the pathophysiology of autoimmune and…”
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BRAFV600E Inhibitor Radiosensitizes Thyroid Cancer—Letter by Göttgens, Eva-Leonne, Rabold, Katrin, Span, Paul N.

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Kinase Inhibitors’ Effects on Innate Immunity in Solid Cancers by Peng, Chunying, Rabold, Katrin, Mulder, Willem J. M., Jaeger, Martin, Netea-Maier, Romana T.

“…Innate immune cells constitute a plastic and heterogeneous cell population of the tumor microenvironment. Because of their high tumor infiltration and close…”
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Metabolic programming of tumor associated macrophages in the context of cancer treatment by Crezee, Thomas, Rabold, Katrin, de Jong, Lisanne, Jaeger, Martin, Netea-Maier, Romana T.

“…Tumor associated macrophages (TAMs) are important components of the tumor microenvironment (TME). They are characterized by a remarkable functional plasticity,…”
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RORα negatively regulates BCG-induced trained immunity by Kilic, Gizem, Matzaraki, Vasiliki, Bulut, Ozlem, Baydemir, Ilayda, Ferreira, Anaisa V., Rabold, Katrin, Moorlag, Simone J.C.F.M., Koeken, Valerie A.C.M., de Bree, L. Charlotte J., Mourits, Vera P., Joosten, Leo A.B., Domínguez-Andrés, Jorge, Netea, Mihai G.

“…[Display omitted] •Polymorphisms in RORA and BCG-induced trained immunity are strongly associated.•The RORα inverse agonist SR3335 induces trained immunity in…”
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Reprogramming of myeloid cells and their progenitors in patients with non-medullary thyroid carcinoma by Rabold, Katrin, Zoodsma, Martijn, Grondman, Inge, Kuijpers, Yunus, Bremmers, Manita, Jaeger, Martin, Zhang, Bowen, Hobo, Willemijn, Bonenkamp, Han J., de Wilt, Johannes H. W., Janssen, Marcel J. R., Cornelissen, Lenneke A. M., van Engen-van Grunsven, Ilse C. H., Mulder, Willem J. M., Smit, Jan W. A., Adema, Gosse J., Netea, Mihai G., Li, Yang, Xu, Cheng-Jian, Netea-Maier, Romana T.

“…Myeloid cells, crucial players in antitumoral defense, are affected by tumor-derived factors and treatment. The role of myeloid cells and their progenitors…”
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T‐Cell Lymphopenia in Patients with Advanced Thyroid Carcinoma Is Associated with Poor Prognosis by Rabold, Katrin, Gielen, Paul R., Kers‐Rebel, Esther D., Netea, Mihai G., Smit, Jan W.A., Adema, Gosse J., Netea‐Maier, Romana T.

“…Background Aggressive forms of thyroid carcinoma (TC) show an abundant infiltration of immune cells, and this correlates with prognosis. However, little is…”
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In vitro induction of trained immunity in adherent human monocytes by Domínguez-Andrés, Jorge, Arts, Rob J.W., Bekkering, Siroon, Bahrar, Harsh, Blok, Bastiaan A., de Bree, L. Charlotte J., Bruno, Mariolina, Bulut, Özlem, Debisarun, Priya A., Dijkstra, Helga, Cristina dos Santos, Jéssica, Ferreira, Anaísa V., Flores-Gomez, Daniela, Groh, Laszlo A., Grondman, Inge, Helder, Leonie, Jacobs, Cor, Jacobs, Liesbeth, Jansen, Trees, Kilic, Gizem, Klück, Viola, Koeken, Valerie A.C.M., Lemmers, Heidi, Moorlag, Simone J.C.F.M., Mourits, Vera P., van Puffelen, Jelmer H., Rabold, Katrin, Röring, Rutger J., Rosati, Diletta, Tercan, Helin, van Tuijl, Julia, Quintin, Jessica, van Crevel, Reinout, Riksen, Niels P., Joosten, Leo A.B., Netea, Mihai G.

“…A growing number of studies show that innate immune cells can undergo functional reprogramming, facilitating a faster and enhanced response to heterologous…”
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IGF2 is a potential factor in RAI‑refractory differentiated thyroid cancer by Crezee, Thomas, Tesselaar, Marika, Jaeger, Martin, Rabold, Katrin, Corver, Willem, Morreau, Hans, Grunsven, Adriana, Smit, Jan, Netea‑Maier, Romana, Plantinga, Theo

“…Differentiated thyroid cancer (DTC) is the most frequent endocrine tumor with a good prognosis after primary treatment in most cases. By contrast, 30-40% of…”
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Interplay between thyroid cancer cells and macrophages: effects on IL-32 mediated cell death and thyroid cancer cell migration by Sloot, Yvette J. E., Rabold, Katrin, Ulas, Thomas, De Graaf, Dennis M., Heinhuis, Bas, Händler, Kristian, Schultze, Joachim L., Netea, Mihai G., Smit, Johannes W. A., Joosten, Leo A. B., Netea-Maier, Romana T.

“…Purpose Interleukin 32 (IL-32) is a pro-inflammatory cytokine of which different isoforms have been identified. Recently, IL-32 has been shown to act as a…”
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Copy number variations as potential diagnostic and prognostic markers for CNS melanocytic neoplasms in neurocutaneous melanosis by van Engen-van Grunsven, Adriana C. H., Rabold, Katrin, Küsters-Vandevelde, Heidi V. N., Rijntjes, Jos, Djafarihamedani, Melika, Hehir-Kwa, Jayne Y., Küsters, Benno, Willemsen, Michel A. A. P., van der Burgt, Ineke, Wesseling, Pieter, Blokx, Willeke A. M., Groenen, Patricia J. T. A.

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NRAS-mutated melanocytic BAP1-associated intradermal tumor (MBAIT): a case report by Blokx, Willeke A. M., Rabold, Katrin, Bovenschen, H. Jorn, Ligtenberg, Marjolijn J. L., Mensenkamp, Arjen R., van Lijnschoten, Gesina, van Zelst-Stams, Wendy A. G., Groenen, Patricia J. T. A.

“…Melanocytic BAP1-associated intradermal tumors (MBAITs) are epithelioid spitzoid looking, mostly intradermally located melanocytic tumors that often have…”
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