Search Results - "Rabin, Richard A."

Effects of chronic ethanol administration on brain protein levels: A proteomic investigation using 2-D DIGE system by Damodaran, Senthilkumar, Dlugos, Cynthia A., Wood, Troy D., Rabin, Richard A.

“…The effects of chronic ethanol treatment on the brain proteome were investigated in the long-fin striped strain of zebrafish Danio rerio. Prolonged exposure to…”
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Statins decrease expression of the proinflammatory neuropeptides calcitonin gene-related peptide and substance P in sensory neurons by Bucelli, Robert C, Gonsiorek, Eugene A, Kim, Woo-Yang, Bruun, Donald, Rabin, Richard A, Higgins, Dennis, Lein, Pamela J

“…Clinical and experimental observations suggest that statins may be useful for treating diseases presenting with predominant neurogenic inflammation, but the…”
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Hallucinogen-like actions of 2,5-dimethoxy-4-(n)-propylthiophenethylamine (2C-T-7) in mice and rats by FANTEGROSSI, William E, HARRINGTON, Andrew W, ECKLER, Justin R, ARSHAD, Sadia, RABIN, Richard A, WINTER, Jerrold C, COOP, Andrew, RICE, Kenner C, WOODS, James H

“…Few studies have examined the effects of 2,5-dimethoxy-4-(n)-propylthiophenethylamine (2C-T-7) in vivo. 2C-T-7 was tested in a drug-elicited head twitch assay…”
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Evaluating Peptide Mass Fingerprinting-based Protein Identification by Damodaran, Senthilkumar, Wood, Troy D., Nagarajan, Priyadharsini, Rabin, Richard A.

“…Identification of proteins by mass spectrometry （MS） is an essential step in proteomic studies and is typically accomplished by either peptide mass…”
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A comparison of imputation procedures and statistical tests for the analysis of two-dimensional electrophoresis data by Miecznikowski, Jeffrey C, Damodaran, Senthilkumar, Sellers, Kimberly F, Rabin, Richard A

“…Numerous gel-based softwares exist to detect protein changes potentially associated with disease. The data, however, are abundant with technical and structural…”
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A comparison of imputation procedures and statistical tests for the analysis of two-dimensional electrophoresis data by Miecznikowski, Jeffrey C, Damodaran, Senthilkumar, Sellers, Kimberly F, Coling, Donald E, Salvi, Richard, Rabin, Richard A

“…Author details1-Department of Biostatistics, University at Buffalo, Buffalo NY 14214 USAEMPTY2-Department of Pharmacology and Toxicology, School of Medicine…”
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Structural and Functional Effects of Developmental Exposure to Ethanol on the Zebrafish Heart by Dlugos, Cynthia A., Rabin, Richard A.

“…Background:  Fetal alcohol exposure during development results in a host of cardiac abnormalities including atrial and ventricular septal defects, teratology…”
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Ocular deficits associated with alcohol exposure during zebrafish development by Dlugos, Cynthia A., Rabin, Richard A.

“…Approximately 90% of fetal alcohol syndrome cases are accompanied by ocular abnormalities. The zebrafish (Danio rerio) is a well‐known developmental model that…”
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Ethanol effects on three strains of zebrafish: model system for genetic investigations by Dlugos, Cynthia A, Rabin, Richard A

“…The effects of acute and chronic ethanol administration on the wild-type (WT), long-fin striped (LFS), and blue long-fin (BLF) strains of zebrafish were…”
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Gender differences in ethanol-induced behavioral sensitivity in zebrafish by Dlugos, Cynthia A, Brown, Shereene J, Rabin, Richard A

“…Abstract Gender-related differential sensitivity to ethanol has long been recognized. Our previous studies have demonstrated that the zebrafish, an animal…”
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Mechanism of ethanol enhancement of apoptosis and caspase activation in serum-deprived PC12 cells by Krzyzanski, Wojciech, Oberdoester, Jan, Rabin, Richard A.

“…Neuronal death is one of the most prominent consequences of alcohol exposure during development. Ethanol-induced neuronal death appears to involve apoptosis…”
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Lysergic acid diethylamide and [−]-2,5-dimethoxy-4-methylamphetamine increase extracellular glutamate in rat prefrontal cortex by Muschamp, John W., Regina, Meredith J., Hull, Elaine M., Winter, Jerrold C., Rabin, Richard A.

“…The ability of hallucinogens to increase extracellular glutamate in the prefrontal cortex (PFC) was assessed by in vivo microdialysis. The hallucinogen…”
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Role of serotonergic 5-HT2A receptors in the psychotomimetic actions of phencyclidine by Rabin, Richard A., Doat, Mireille, Winter, Jerrold C.

“…The psychotomimetic phencyclidine (PCP) alters various behavioural responses involving the serotonergic system including potentiating the discriminative…”
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d-LSD-induced c-Fos expression occurs in a population of oligodendrocytes in rat prefrontal cortex by Reissig, Chad J., Rabin, Richard A., Winter, Jerrold C., Dlugos, Cynthia A.

“…Induction of mRNA or protein for immediate–early genes, such as c- fos, is used to identify brain areas, specific cell types, and neuronal circuits that become…”
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Minimizing variability in two-dimensional electrophoresis gel image analysis by Damodaran, Senthilkumar, Rabin, Richard A

“…For reliable protein identification and quantitation, it is important to minimize the variability associated with two-dimensional electrophoresis (2-DE)…”
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5-HT2A receptor-stimulated phosphoinositide hydrolysis in the stimulus effects of hallucinogens by RABIN, Richard A, REGINA, Meredith, DOAT, Mireille, WINTER, J. C

“…The role of 5-HT2A-mediated stimulation of phosphoinositide hydrolysis in the discriminative effects of hallucinogens was investigated in PC12 cells stably…”
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Enhanced caspase activity during ethanol-induced apoptosis in rat cerebellar granule cells by Oberdoerster, Jan, Rabin, Richard A

“…The effects of ethanol on cerebellar granule cell death were examined in cultures maintained for either 5 days in vitro (immature) or 8 and 12 days in vitro…”
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Characterization of a novel effect of serotonin 5-HT1A and 5-HT2A receptors: increasing cGMP levels in rat frontal cortex by REGINA, Meredith J, WINTER, Jerrold C, RABIN, Richard A

“…Elucidating the mechanisms of action of hallucinogens has become an increasingly important area of research as their abuse has grown in recent years. Although…”
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Cellular mechanisms of serotonin 5-HT2A receptor-mediated cGMP formation: the essential role of glutamate by REGINA, Meredith J, BUCELLI, Robert C, WINTER, Jerrold C, RABIN, Richard A

“…The current study explores the mechanisms by which activation of serotonin(2A) (5-HT(2A)) receptors increase production of cyclic guanosine monophosphate…”
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Differential effect of ethanol on PC12 cell death by Oberdoerster, J, Kamer, A R, Rabin, R A

“…Our goal was to examine the effects of ethanol on cell death using rat pheochromocytoma (PC12) cells as a neuronal model. Withdrawal of serum for 24 hr…”
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