Search Results - "Raber, Kerstin"

Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition by Siebzehnrübl, Florian A., Raber, Kerstin A., Urbach, Yvonne K., Schulze-Krebs, Anja, Canneva, Fabio, Moceri, Sandra, Habermeyer, Johanna, Achoui, Dalila, Gupta, Bhavana, Steindler, Dennis A., Stephan, Michael, Nguyen, Huu Phuc, Bonin, Michael, Riess, Olaf, Bauer, Andreas, Aigner, Ludwig, Couillard-Despres, Sebastien, Paucar, Martin Arce, Svenningsson, Per, Osmand, Alexander, Andreew, Alexander, Zabel, Claus, Weiss, Andreas, Kuhn, Rainer, Moussaoui, Saliha, Blockx, Ines, Van der Linden, Annemie, Cheong, Rachel Y., Roybon, Laurent, Petersén, Åsa, von Hörsten, Stephan

“…Huntington disease (HD) is an autosomal dominant neurodegenerative disorder caused by expanded CAG repeats in the huntingtin gene (HTT). Although mutant HTT is…”
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Selective hippocampal neurodegeneration in transgenic mice expressing small amounts of truncated Aβ is induced by pyroglutamate-Aβ formation by Alexandru, Anca, Jagla, Wolfgang, Graubner, Sigrid, Becker, Andreas, Bäuscher, Christoph, Kohlmann, Stephanie, Sedlmeier, Reinhard, Raber, Kerstin A, Cynis, Holger, Rönicke, Raik, Reymann, Klaus G, Petrasch-Parwez, Elisabeth, Hartlage-Rübsamen, Maike, Waniek, Alexander, Rossner, Steffen, Schilling, Stephan, Osmand, Alexander P, Demuth, Hans-Ulrich, von Hörsten, Stephan

“…Posttranslational amyloid-β (Aβ) modification is considered to play an important role in Alzheimer's disease (AD) etiology. An N-terminally modified Aβ…”
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Automated phenotyping and advanced data mining exemplified in rats transgenic for Huntington's disease by Urbach, Yvonne K., Raber, Kerstin A., Canneva, Fabio, Plank, Anne-C., Andreasson, Theresa, Ponten, Henrik, Kullingsjö, Johan, Nguyen, Huu Phuc, Riess, Olaf, von Hörsten, Stephan

“…The need for improving throughput, validity, and reliability in the behavioral characterization of rodents may benefit from integrating automated…”
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Early Alterations in Operant Performance and Prominent Huntingtin Aggregation in a Congenic F344 Rat Line of the Classical CAGn51trunc Model of Huntington Disease by Plank, Anne-Christine, Canneva, Fabio, Raber, Kerstin A., Urbach, Yvonne K., Dobner, Julia, Puchades, Maja, Bjaalie, Jan G., Gillmann, Clarissa, Bäuerle, Tobias, Riess, Olaf, Nguyen, Hoa H. P., von Hörsten, Stephan

“…The transgenic rat model of Huntington disease expressing a fragment of mutant HTT (tgHD rat) has been thoroughly characterized and reproduces hallmark…”
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Sex differences in a transgenic rat model of Huntington's disease: decreased 17β-estradiol levels correlate with reduced numbers of DARPP32+ neurons in males by Bode, Felix J., Stephan, Michael, Suhling, Hendrik, Pabst, Reinhard, Straub, Rainer H., Raber, Kerstin A., Bonin, Michael, Nguyen, Huu Phuc, Riess, Olaf, Bauer, Andreas, Sjoberg, Charlotte, Petersén, Åsa, von Hörsten, Stephan

“…Recent clinical studies have highlighted that female sex hormones represent potential neuroprotective mediators against damage caused by acute and chronic…”
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Stem Cell Quiescence in the Hippocampal Neurogenic Niche Is Associated With Elevated Transforming Growth Factor-β Signaling in an Animal Model of Huntington Disease by Kandasamy, Mahesh, Couillard-Despres, Sebastien, Raber, Kerstin A, Stephan, Michael, Lehner, Bernadette, Winner, Beate, Kohl, Zacharias, Rivera, Francisco J, Nguyen, Huu Phuc, Riess, Olaf, Bogdahn, Ulrich, Winkler, Jürgen, von Hörsten, Stephan, Aigner, Ludwig

“…Cellular proliferation, differentiation, integration, and survival within the adult neural stem cell niche are altered under pathological conditions, but the…”
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Regulation of Expression and Function of Dipeptidyl Peptidase 4 (DP4), DP8/9, and DP10 in Allergic Responses of the Lung in Rats by Schade, Jutta, Stephan, Michael, Schmiedl, Andreas, Wagner, Leona, Niestroj, Andre J, Demuth, Hans-Ulrich, Frerker, Nadine, Klemann, Christian, Raber, Kerstin A, Pabst, Reinhard, von Horsten, Stephan

“…The expression of dipeptidyl peptidase 4 (DP4, CD26) affects T-cell recruitment to lungs in an experimental rat asthma model. Furthermore, the gene of the…”
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Altered hypothalamic protein expression in a rat model of Huntington's disease by Cong, Wei-na, Cai, Huan, Wang, Rui, Daimon, Caitlin M, Maudsley, Stuart, Raber, Kerstin, Canneva, Fabio, von Hörsten, Stephan, Martin, Bronwen

“…Huntington's disease (HD) is a neurodegenerative disorder, which is characterized by progressive motor impairment and cognitive alterations. Changes in energy…”
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Identification and characterization of Huntington related pathology: An in vivo DKI imaging study by Blockx, Ines, Verhoye, Marleen, Van Audekerke, Johan, Bergwerf, Irene, Kane, Jack X., Delgado y Palacios, Rafael, Veraart, Jelle, Jeurissen, Ben, Raber, Kerstin, von Hörsten, Stephan, Ponsaerts, Peter, Sijbers, Jan, Leergaard, Trygve B., Van der Linden, Annemie

“…An important focus of Huntington Disease (HD) research is the identification of symptom-independent biomarkers of HD neuropathology. There is an urgent need…”
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Effects of dipeptidyl peptidase‐4 inhibition in an animal model of experimental asthma: a matter of dose, route, and time by Stephan, Michael, Suhling, Hendrik, Schade, Jutta, Wittlake, Mareike, Tasic, Tihana, Klemann, Christian, Pabst, Reinhard, Jurawitz, Marie‐Charlot, Raber, Kerstin A., Hoymann, Heinz G., Braun, Armin, Glaab, Thomas, Hoffmann, Torsten, Schmiedl, Andreas, Hörsten, Stephan

“…The CD26‐associated enzymatic activity of dipeptidyl peptidase‐4 (DPP4) as well as the recruitment of CD26+ T cells increase under allergic airway…”
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Selective striatal neuron loss and alterations in behavior correlate with impaired striatal function in Huntington's disease transgenic rats by Kántor, Orsolya, Temel, Yasin, Holzmann, Carsten, Raber, Kerstin, Nguyen, Huu-Phuc, Cao, Chunyan, Türkoglu, Hatice Özen, Rutten, Bart P.F., Visser-Vandewalle, Veerle, Steinbusch, Harry W.M., Blokland, Arjan, Korr, Hubert, Riess, Olaf, von Hörsten, Stephan, Schmitz, Christoph

“…Huntington's disease (HD) is an inherited neurodegenerative disorder characterized by selective striatal neuron loss and motor, cognitive and affective…”
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Dipeptidyl peptidase expression during experimental colitis in mice by Yazbeck, Roger, Sulda, Melanie L., Howarth, Gordon S., Bleich, Andre, Raber, Kerstin, von Hörsten, Stephan, Holst, Jens Juul, Abbott, Catherine A.

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Microstructural changes observed with DKI in a transgenic Huntington rat model: Evidence for abnormal neurodevelopment by Blockx, Ines, De Groof, Geert, Verhoye, Marleen, Van Audekerke, Johan, Raber, Kerstin, Poot, Dirk, Sijbers, Jan, Osmand, Alexander P., Von Hörsten, Stephan, Van der Linden, Annemie

“…Huntington Disease (HD) is a fatal neurodegenerative disorder, caused by a mutation in the Huntington gene. Although HD is most often diagnosed in mid-life,…”
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Dipeptidyl peptidase expression during experimental colitis in mice by Yazbeck, Roger, Sulda, Melanie L., Howarth, Gordon S., Bleich, Andre, Raber, Kerstin, von Hörsten, Stephan, Holst, Jens Juul, Abbott, Catherine A.

“…Background: We have previously demonstrated that inhibition of dipeptidyl peptidase (DP) activity partially attenuates dextran sulfate sodium (DSS) colitis in…”
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Early Alterations in Operant Performance and Prominent Huntingtin Aggregation in a Congenic F344 Rat Line of the Classical CAG n51trunc Model of Huntington Disease by Plank, Anne-Christine, Canneva, Fabio, Raber, Kerstin A, Urbach, Yvonne K, Dobner, Julia, Puchades, Maja, Bjaalie, Jan G, Gillmann, Clarissa, Bäuerle, Tobias, Riess, Olaf, Nguyen, Hoa H P, von Hörsten, Stephan

“…The transgenic rat model of Huntington disease expressing a fragment of mutant HTT (tgHD rat) has been thoroughly characterized and reproduces hallmark…”
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Genotype specific age related changes in a transgenic rat model of Huntington's disease by Blockx, Ines, Van Camp, Nadja, Verhoye, Marleen, Boisgard, Raphael, Dubois, Albertine, Jego, Benoit, Jonckers, Elisabeth, Raber, Kerstin, Siquier, Karine, Kuhnast, Bertrand, Dollé, Frédéric, Nguyen, Huu Phuc, Von Hörsten, Stephan, Tavitian, Bertrand, Van der Linden, Annemie

“…We aimed to characterize the transgenic Huntington rat model with in vivo imaging and identify sensitive and reliable biomarkers associated with early and…”
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Neuropeptide Y receptor-specifically modulates human neutrophil function by Bedoui, Sammy, Kromer, Andreas, Gebhardt, Thomas, Jacobs, Roland, Raber, Kerstin, Dimitrijevic, Mirja, Heine, Jörn, von Hörsten, Stephan

“…Abstract Despite a continuously growing body of evidence highlighting the role of NPY in the immune system, surprisingly little is known about its ability to…”
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Postnatal Life Events Affect the Severity of Asthmatic Airway Inflammation in the Adult Rat by Kruschinski, Carsten, Skripuletz, Thomas, Bedoui, Sammy, Raber, Kerstin, Straub, Rainer H, Hoffmann, Torsten, Grote, Karsten, Jacobs, Roland, Stephan, Michael, Pabst, Reinhard, von Horsten, Stephan

“…Genetic and hygienic factors influence susceptibility to asthma. In autoimmune and inflammatory diseases, additional effects of the psychosocial environment…”
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Correction: Altered Hypothalamic Protein Expression in a Rat Model of Huntington's Disease by Cong, Wei-na, Cai, Huan, Wang, Rui, Daimon, Caitlin M., Maudsley, Stuart, Raber, Kerstin, Canneva, Fabio, von Hörsten, Stephan, Martin, Bronwen

“…There was an error in the Funding statement. (2012) Correction: Altered Hypothalamic Protein Expression in a Rat Model of Huntington's Disease…”
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Phenotyping of congenic dipeptidyl peptidase 4 (DP4) deficient Dark Agouti (DA) rats suggests involvement of DP4 in neuro-, endocrine, and immune functions by Frerker, Nadine, Raber, Kerstin, Bode, Felix, Skripuletz, Thomas, Nave, Heike, Klemann, Christian, Pabst, Reinhard, Stephan, Michael, Schade, Jutta, Brabant, Georg, Wedekind, Dirk, Jacobs, Roland, Jörns, Anne, Forssmann, Ulf, Straub, Rainer H, Johannes, Sigrid, Hoffmann, Torsten, Wagner, Leona, Demuth, Hans-Ulrich, von Hörsten, Stephan

“…Treatment of diabetes type 2 using chronic pharmacological inhibition of dipeptidyl peptidase 4 (DP4) still requires an in-depth analysis of models for chronic…”
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