Search Results - "Raben, Daniel M"

Lipid Metabolism Crosstalk in the Brain: Glia and Neurons by Barber, Casey N, Raben, Daniel M

“…Until recently, glial cells have been considered mainly support cells for neurons in the mammalian brain. However, many studies have unveiled a variety of…”
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The role of N-terminal phosphorylation of DGK-θ by Barbernitz, Millie X., Devine, Lauren R., Cole, Robert N., Raben, Daniel M.

“…Diacylglycerol kinases (DGKs) are lipid kinases that mediate the phosphorylation of diacylglycerol (DAG) leading to the production of phosphatidic acid…”
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TRPV2 has a pivotal role in macrophage particle binding and phagocytosis by Link, Tiffany M, Park, Una, Vonakis, Becky M, Raben, Daniel M, Soloski, Mark J, Caterina, Michael J

“…Phagocytosis involves ionic flux, but the identity of the ion channels involved remains ill defined. Caterina and co-workers show that the cation channel TRPV2…”
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Differential expression patterns of phospholipase D isoforms 1 and 2 in the mammalian brain and retina by Barber, Casey N., Goldschmidt, Hana L., Lilley, Brendan, Bygrave, Alexei M., Johnson, Richard C., Huganir, Richard L., Zack, Donald J., Raben, Daniel M.

“…Phosphatidic acid is a key signaling molecule heavily implicated in exocytosis due to its protein-binding partners and propensity to induce negative membrane…”
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sphingosine and diacylglycerol kinase superfamily of signaling kinases: localization as a key to signaling function by Wattenberg, Binks W, Pitson, Stuart M, Raben, Daniel M

“…The sphingosine and diacylglycerol kinases form a superfamily of structurally related lipid signaling kinases. One of the striking features of these kinases is…”
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DGKθ Catalytic Activity Is Required for Efficient Recycling of Presynaptic Vesicles at Excitatory Synapses by Goldschmidt, Hana L., Tu-Sekine, Becky, Volk, Lenora, Anggono, Victor, Huganir, Richard L., Raben, Daniel M.

“…Synaptic transmission relies on coordinated coupling of synaptic vesicle (SV) exocytosis and endocytosis. While much attention has focused on characterizing…”
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Phosphatidic acid-producing enzymes regulating the synaptic vesicle cycle: Role for PLD? by Barber, Casey N., Huganir, Richard L., Raben, Daniel M.

“…In cortical and hippocampal neurons of the mammalian brain, the synaptic vesicle cycle is a series of steps that tightly regulate exo- and endocytosis of…”
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Identification of Synaptic DGKθ Interactors That Stimulate DGKθ Activity by Barber, Casey N, Goldschmidt, Hana L, Ma, Qianqian, Devine, Lauren R, Cole, Robert N, Huganir, Richard L, Raben, Daniel M

“…Lipids and their metabolic enzymes are a critical point of regulation for the membrane curvature required to induce membrane fusion during synaptic vesicle…”
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Bacterial expression strategies for several Sus scrofa diacylglycerol kinase alpha constructs: solubility challenges by Petro, Elizabeth J., Raben, Daniel M.

“…We pursued several strategies for expressing either full-length Sus scrofa diacylglycerol kinase (DGK) alpha or the catalytic domain (alphacat) in Escherichia…”
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Nuclear diacylglycerol kinases: regulation and roles by Raben, Daniel M, Tu-Sekine, Becky

“…The diacylglycerol-kinases are a family of related lipid kinases. There are currently 10 known isoforms of diacylglycerol kinases that are categorized into…”
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A new method for quantifying the enzyme activity of DGKs by Barbernitz, Millie Xin, Raben, Daniel M.

“…Diacylglycerol kinases (DGKs) are a family of enzymes that catalyze the ATP-dependent conversion of diacylglycerol (DAG) to phosphatidic acid (PtdOH). A common…”
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The expression of diacylglycerol kinase theta during the organogenesis of mouse embryos by Ueda, Shuji, Tu-Sekine, Becky, Yamanoue, Minoru, Raben, Daniel M, Shirai, Yasuhito

“…Diacylglycerol kinase (DGK) is a key enzyme that regulates diacylglycerol (DG) turnover and is involved in a variety of physiological functions. The isoform…”
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Phosphorylation of DGK by Barbernitz, Xin, Raben, Daniel M.

“…Diacylglycerol (DAG) and phosphatidic acid (PtdOH) play important roles in a variety of signaling cascades (Carrasco and Merida, 2007; Stace and Ktistakis,…”
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DGK-θ: Structure, Enzymology, and Physiological Roles by Tu-Sekine, Becky, Goldschmidt, Hana L, Raben, Daniel M

“…Diacylglycerol kinases (DGKs) are a family of enzymes that catalyze the ATP-dependent phosphorylation of diacylglycerol (DAG) to phosphatidic acid (PtdOH). The…”
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Signaling at the membrane interface by the DGK/SK enzyme family by Raben, Daniel M., Wattenberg, Binks W.

“…The sphingosine (SK) and diacylglycerol (DGK) kinases have become the subject of considerable focus recently due to their involvement as signaling enzymes in a…”
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Phosphatidic acid and neurotransmission by Raben, Daniel M., Barber, Casey N.

“…Lipids play a vital role in the health and functioning of neurons and interest in the physiological role of neuronal lipids is certainly increasing. One…”
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Elusive structure of mammalian DGKs by Ma, Qianqian, Srinivasan, Lakshmi, Gabelli, Sandra B., Raben, Daniel M.

“…Mammalian diacylglycerol kinases (DGKs) are a group of enzymes that catalyze the ATP-dependent phosphorylation of diacylglycerol (DAG) to produce phosphatidic…”
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Diacylglycerol kinases: Relationship to other lipid kinases by Ma, Qianqian, Gabelli, Sandra B., Raben, Daniel M.

“…Lipid kinases regulate a wide variety of cellular functions and have emerged as one the most promising targets for drug design. Diacylglycerol kinases (DGKs)…”
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In Memoriam: M. Daniel Lane (1930–2014) by Raben, Daniel M.

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Roles of DGKs in neurons: Postsynaptic functions? by Barber, Casey N., Raben, Daniel M.

“…Diacylglycerol kinases (DGKs) contribute to an important part of intracellular signaling because, in addition to reducing diacylglycerol levels, they generate…”
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