Search Results - "Rabelo‐Fernandez, Robert"
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The metabolic baton: conducting the dance of N6-methyladenosine writing and erasing
Published in Current opinion in genetics & development (01-06-2024)“…The modification N6-methyladenosine (m6A) plays an important role in determining the functional output of gene expression programs. Throughout the…”
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Reduced RBPMS Levels Promote Cell Proliferation and Decrease Cisplatin Sensitivity in Ovarian Cancer Cells
Published in International journal of molecular sciences (04-01-2022)“…Worldwide, the number of cancer-related deaths continues to increase due to the ability of cancer cells to become chemotherapy-resistant and metastasize. For…”
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Upregulation of the Long Noncoding RNA CASC10 Promotes Cisplatin Resistance in High-Grade Serous Ovarian Cancer
Published in International journal of molecular sciences (13-07-2022)“…Despite initial responses to first-line treatment with platinum and taxane-based combination chemotherapy, most high-grade serous ovarian carcinoma (HGSOC)…”
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Reduced expression of enolase-1 correlates with high intracellular glucose levels and increased senescence in cisplatin-resistant ovarian cancer cells
Published in American journal of translational research (01-01-2020)“…Despite good responses to first-line treatment with platinum-based combination chemotherapy, most ovarian cancer patients will relapse and eventually develop a…”
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MicroRNA-92b targets tumor suppressor gene FBXW7 in glioblastoma
Published in Frontiers in oncology (11-09-2023)“…Glioblastoma (GBM) is a highly aggressive and lethal primary brain tumor. Despite limited treatment options, the overall survival of GBM patients has shown…”
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Microbial Model Construction Activity for Introducing Students to Microbiome and Metagenomic Fields
Published in Journal of microbiology & biology education (01-09-2021)“…Educational activities in biology teaching focused on model construction allow students to make the invisible evident. The development and integration of these…”
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A Fresh Look at the Potential of Cyclodextrins for Improving the Delivery of siRNA Encapsulated in Liposome Nanocarriers
Published in ACS omega (01-02-2022)“…Liposomes are among the most effective vehicles to deliver siRNAs to cells, both in vitro and in vivo. However, despite numerous efforts to improve the…”
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The metagenome of Caracolus marginella gut microbiome using culture independent approaches and shotgun sequencing
Published in Data in brief (01-02-2018)“…Studies underestimate the microbial diversity and genotypic traits in the snails’ microbiome. Caracolus marginella, a land snail native to Caribbean islands,…”
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Role of RNA Binding Protein with Multiple Splicing (RBPMS) Variants in Cell Proliferation, Invasion and Angiogenesis in Ovarian Cancer
Published in The FASEB journal (01-05-2022)“…Worldwide, the number of cancer‐related deaths continues to increase due to the ability of cancer cells to become chemotherapy‐resistant and metastasize. For…”
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Increased Expression of the RBPMS Splice Variants Inhibits Cell Proliferation in Ovarian Cancer Cells
Published in International journal of molecular sciences (25-11-2022)“…RNA-Binding Protein with Multiple Splicing (RBPMS) is a member of family proteins that bind to nascent RNA transcripts and regulate their splicing,…”
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Decreased RBPMS Levels Promote Cell Proliferation, Invasion, Angiogenesis, in Cisplatin Resistant Ovarian Cancer Cells
Published in The FASEB journal (01-05-2021)“…RBPMS is a RNA binding protein with multiple splicing encoded by the RBPMS gene located in chromosome eight in humans. Three major RBPMS isoforms have been…”
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Abstract A68: Increasing intracellular glucose levels decreased expression of Enolase-I promoting cisplatin resistance in ovarian cancer cells
Published in Clinical cancer research (01-07-2020)“…Abstract Cytoreductive surgery in combination with platinum-based chemotherapy has been used for more than four decades for treat ovarian cancer. Although…”
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Decreased Expression of Enolase‐I Promotes Cisplatin Resistance of Ovarian Cancer Cells
Published in The FASEB journal (01-04-2019)“…Platinum‐containing anticancer drugs has been used for more than four decades has effective treatment for ovarian cancer and many others solid tumors. However,…”
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Abstract 2503: Crispr/cas-9-mediated genome editing reveals that RBPMS acts as a tumor suppressor in ovarian cancer
Published in Cancer research (Chicago, Ill.) (01-07-2021)“…Abstract RNA-Binding Protein with Multiple Splicing (RBPMS) is a member of a family of proteins that bind to the nascent RNA transcripts and regulate their…”
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Unraveling the Role of RNA Binding Protein with Multiple Splicing (RBPMS) in Ovarian Cancer Cells
Published 01-01-2023“…RNA-Binding Protein with Multiple Splicing (RBPMS) is member of a family of proteins that bind to nascent RNA transcripts and regulate their splicing,…”
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Dissertation -
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Erratum: Reduced expression of enolase-1 correlates with high intracellular glucose levels and increased senescence in cisplatin-resistant ovarian cancer cells
Published in American journal of translational research (2021)“…[This corrects the article on p. 1275 in vol. 12, PMID: 32355541.]…”
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