Search Results - "Rabe, Anthony J."

Strategies for Targeting Retroviral Integration for Safer Gene Therapy: Advances and Challenges by Yoder, Kristine E, Rabe, Anthony J, Fishel, Richard, Larue, Ross C

“…Retroviruses are obligate intracellular parasites that must integrate a copy of the viral genome into the host DNA. The integration reaction is performed by…”
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Prototype Foamy Virus Integrase Displays Unique Biochemical Activities among Retroviral Integrases by Rabe, Anthony J, Tan, Yow Yong, Larue, Ross C, Yoder, Kristine E

“…Integrases of different retroviruses assemble as functional complexes with varying multimers of the protein. Retroviral integrases require a divalent metal…”
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Retroviral prototype foamy virus intasome binding to a nucleosome target does not determine integration efficiency by Kotlar, Randi M., Jones, Nathan D., Senavirathne, Gayan, Gardner, Anne M., Messer, Ryan K., Tan, Yow Yong, Rabe, Anthony J., Fishel, Richard, Yoder, Kristine E.

“…Retroviral integrases must navigate host DNA packaged as chromatin during integration of the viral genome. Prototype foamy virus (PFV) integrase (IN) forms a…”
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