Search Results - "Rabb, Hamid"
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Kidney diseases in the time of COVID-19: major challenges to patient care
Published in The Journal of clinical investigation (01-06-2020)“…The late Colombian Nobel Prize-winning author Gabriel Garcia Marquez wrote "Love in the Time of Cholera," a complex depiction of the struggle to love during an…”
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Impact of acute kidney injury on distant organ function: recent findings and potential therapeutic targets
Published in Kidney international (01-03-2016)“…Acute kidney injury (AKI) is a common complication in critically ill patients and subsequently worsens outcomes. Although many drugs to prevent and treat AKI…”
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3
Improving the Supply and Quality of Deceased-Donor Organs for Transplantation
Published in The New England journal of medicine (17-05-2018)“…Solid-organ transplantation is the treatment of choice for many patients with end-stage diseases, but the supply of organs is limited. Recent advances are…”
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Distant Organ Dysfunction in Acute Kidney Injury: A Review
Published in American journal of kidney diseases (01-12-2018)“…Acute kidney injury (AKI) is common in critically ill patients and is associated with increased morbidity and mortality. Dysfunction of other organs is an…”
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The distant organ effects of acute kidney injury
Published in Kidney international (01-05-2012)“…Despite the availability of renal replacement therapy, acute kidney injury (AKI) is associated with high mortality and morbidity. In humans, it is difficult to…”
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Comparison of Life Participation Activities Among Adults Treated by Hemodialysis, Peritoneal Dialysis, and Kidney Transplantation: A Systematic Review
Published in American journal of kidney diseases (01-11-2013)“…Background A comprehensive assessment of the association of patients' renal replacement therapy (RRT) modality with their participation in life activities…”
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7
Beyond kidney dialysis and transplantation: what's on the horizon?
Published in The Journal of clinical investigation (01-04-2022)Get full text
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Role of Immune Cells in Acute Kidney Injury and Repair
Published in Nephron (2015) (01-01-2017)“…Acute kidney injury (AKI) is a significant problem in both native and transplant kidneys. There have been significant advances in understanding the role of…”
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The Local and Systemic Inflammatory Transcriptome after Acute Kidney Injury
Published in Journal of the American Society of Nephrology (01-03-2008)“…Studies in humans and animal models have demonstrated that acute kidney injury (AKI) has a significant effect on the function of extrarenal organs. The…”
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Kidney double positive T cells have distinct characteristics in normal and diseased kidneys
Published in Scientific reports (23-02-2024)“…Multiple types of T cells have been described and assigned pathophysiologic functions in the kidneys. However, the existence and functions of TCR+CD4+CD8+…”
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Transcriptional analysis of kidneys during repair from AKI reveals possible roles for NGAL and KIM-1 as biomarkers of AKI-to-CKD transition
Published in American journal of physiology. Renal physiology (01-06-2010)“…Acute kidney injury (AKI) is being increasingly shown to be a risk factor for chronic kidney disease (CKD), but little is known about the possible mechanistic…”
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The interaction between ischemia–reperfusion and immune responses in the kidney
Published in Journal of molecular medicine (Berlin, Germany) (01-09-2009)“…Kidney ischemia–reperfusion injury (IRI) engages both the innate and adaptive immune responses. Cellular mediators of immunity, such as dendritic cells,…”
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13
A Prospective Controlled Study of Living Kidney Donors: Three-Year Follow-up
Published in American journal of kidney diseases (01-07-2015)“…Background There have been few prospective controlled studies of kidney donors. Understanding the pathophysiologic effects of kidney donation is important for…”
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Possible kidney-lung cross-talk in COVID-19: in silico modeling of SARS-CoV-2 infection
Published in BMC nephrology (05-02-2022)“…Publicly available genomics datasets have grown drastically during the past decades. Although most of these datasets were initially generated to answer a…”
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Lymphocytes and ischemia-reperfusion injury
Published in Transplantation reviews (Philadelphia, Pa.) (2009)“…Abstract Ischemia reperfusion injury (IRI) is a common and important clinical problem in many different organ systems, including kidney, brain, heart, liver,…”
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Acute Kidney Injury Leads to Inflammation and Functional Changes in the Brain
Published in Journal of the American Society of Nephrology (01-07-2008)“…Although neurologic sequelae of acute kidney injury (AKI) are well described, the pathogenesis of acute uremic encephalopathy is poorly understood. This study…”
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Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice
Published in Kidney international (01-08-2009)“…Oxidative stress is involved in acute kidney injury due to ischemia–reperfusion and chemotherapy-induced nephrotoxicity. To investigate their basic mechanisms…”
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KEAP1 Editing Using CRISPR/Cas9 for Therapeutic NRF2 Activation in Primary Human T Lymphocytes
Published in The Journal of immunology (1950) (01-03-2018)“…Oxidant stress modifies T lymphocyte activation and function. Previous work demonstrated that murine T cell-specific kelch like-ECH-associated protein 1 ( )…”
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HuR and other turnover- and translation-regulatory RNA-binding proteins: implications for the kidney
Published in American journal of physiology. Renal physiology (15-03-2014)“…The posttranscriptional regulation of gene expression occurs through cis RNA regulatory elements by the action of trans factors, which are represented by…”
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Single cell and spatial transcriptomics analysis of kidney double negative T lymphocytes in normal and ischemic mouse kidneys
Published in Scientific reports (28-11-2023)“…T cells are important in the pathogenesis of acute kidney injury (AKI), and TCR + CD4 - CD8 - (double negative-DN) are T cells that have regulatory properties…”
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