Search Results - "Rabalski, Adam J"
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Protein Kinase CK2: Intricate Relationships within Regulatory Cellular Networks
Published in Pharmaceuticals (Basel, Switzerland) (05-03-2017)“…Protein kinase CK2 is a small family of protein kinases that has been implicated in an expanding array of biological processes. While it is widely accepted…”
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Molecular Pathways: Emergence of Protein Kinase CK2 (CSNK2) as a Potential Target to Inhibit Survival and DNA Damage Response and Repair Pathways in Cancer Cells
Published in Clinical cancer research (15-06-2016)“…Protein kinase CK2 (designated CSNK2) is a constitutively active protein kinase with a vast repertoire of putative substrates that has been implicated in…”
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Chemical Genetic Validation of CSNK2 Substrates Using an Inhibitor-Resistant Mutant in Combination with Triple SILAC Quantitative Phosphoproteomics
Published in Frontiers in molecular biosciences (09-06-2022)“…Casein Kinase 2 (CSNK2) is an extremely pleiotropic, ubiquitously expressed protein kinase involved in the regulation of numerous key biological processes…”
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Evaluation of Chemically-Cleavable Linkers for Quantitative Mapping of Small Molecule-Cysteinome Reactivity
Published in ACS chemical biology (20-09-2019)“…Numerous reagents have been developed to enable chemical proteomic analysis of small molecule-protein interactomes. However, the performance of these reagents…”
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In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy
Published in Autophagy (01-02-2018)“…In yeast, Tom22, the central component of the TOMM (translocase of outer mitochondrial membrane) receptor complex, is responsible for the recognition and…”
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A Dual‐Purpose Bromocoumarin Tag Enables Deep Profiling of the Cellular Cysteinome
Published in Proteomics (Weinheim) (01-06-2019)“…Chemical proteomics enables comprehensive profiling of small molecules in complex proteomes. A critical component to understand the interactome of a small…”
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Expression patterns of ShcD and Shc family adaptor proteins during mouse embryonic development
Published in Developmental dynamics (01-01-2011)“…The Src homology and collagen (Shc) proteins function as molecular adaptors in signaling pathways mediated by a variety of cell surface receptors. Of the four…”
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Front Cover: A Dual‐Purpose Bromocoumarin Tag Enables Deep Profiling of the Cellular Cysteinome
Published in Proteomics (Weinheim) (01-06-2019)“…DOI: 10.1002/pmic.201800433 Chemical proteomics enables comprehensive profiling of small molecules in complex proteomes. In this study, fluorescence‐triggered…”
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Quantitative Proteomic Characterization of CX-4945, a Clinical Stage Inhibitor of Protein Kinase CK2
Published 01-01-2017“…Protein phosphorylation is controlled by protein kinases, and represents a critical signaling mechanism involved in the regulation of fundamental biological…”
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Dissertation