Cardiovascular Disease and COVID-19 Vaccines: A Systematic Review and Analysis of Published Cases

As vaccination against COVID-19 became more widespread, side-effects that were not initially detected during clinical trials became more prominent. The aim of this systematic review is to discuss reports of adverse cardiovascular events associated with COVID-19 vaccination. Databases were searched f...

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Bibliographic Details
Published in:	European cardiology Vol. 18; p. e54
Main Authors:	Khaity, Abdulrhman, Rababah, Ala' Abdala Mohamad, Abdelwahab, Omar A, Albakri, Khaled, Diab, Rehab Adel, Al-Dardery, Nada Mostafa, Abbassy, Mahmoud, Al-Hanaqtah, Balqees M, Awad, Ahmed K, Mohamad, Tamam
Format:	Journal Article
Language:	English
Published:	England Radcliffe Cardiology 01-01-2023 Radcliffe Medical Media
Subjects:	Environmental Issues for CV Health COVID-19 Cardiovascular disease vaccine systematic review
Online Access:	Get full text
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Summary:	As vaccination against COVID-19 became more widespread, side-effects that were not initially detected during clinical trials became more prominent. The aim of this systematic review is to discuss reports of adverse cardiovascular events associated with COVID-19 vaccination. Databases were searched from inception up to August 2022 to identify case reports and case series reporting on patients with cardiovascular disease after COVID-19 vaccination. This study assessed 150 published cases. Of these, 109 were case reports and 41 were case series. The majority of patients were male (n=302, 86.6%), with a mean age of 27.6 ± 16.7 years. Of the included patients, 268 (76.6%) had myocarditis, 50 (14.6%) had myopericarditis, 8 (2.3%) had pericarditis, and only 4 (1.1%) had stress-induced cardiomyopathy. Moreover, 30 (8.6%) and 11 (3.1%) were diagnosed with arrhythmia and ischaemic heart disease, respectively. Ultimately, cardiovascular complications after COVID-19 vaccination include myocarditis, myopericarditis, ischaemic heart disease and arrhythmia. The young population, especially young male patients, could be more vulnerable to myocarditis.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 Disclosure: The authors have no conflicts of interest to declare.
ISSN:	1758-3756 1758-3764 1758-3764
DOI:	10.15420/ecr.2023.01