Search Results - "Raatgeep, H"

IL-10 signaling prevents gluten-dependent intraepithelial CD4+ cytotoxic T lymphocyte infiltration and epithelial damage in the small intestine by Costes, L. M. M., Lindenbergh-Kortleve, D. J., van Berkel, L. A., Veenbergen, S., Raatgeep, H. (R). C., Simons-Oosterhuis, Y., van Haaften, D. H., Karrich, J. J., Escher, J. C., Groeneweg, M., Clausen, B. E., Cupedo, T., Samsom, J. N.

“…Summary Breach of tolerance to gluten leads to the chronic small intestinal enteropathy celiac disease. A key event in celiac disease development is…”
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Duplication of the IL2RA locus causes excessive IL-2 signaling and may predispose to very early onset colitis by Joosse, Maria E., Charbit-Henrion, Fabienne, Boisgard, Remy, Raatgeep, Rolien (H.) C., Lindenbergh-Kortleve, Dicky J., Costes, Léa M. M., Nugteren, Sandrine, Guegan, Nicolas, Parlato, Marianna, Veenbergen, Sharon, Malan, Valérie, Nowak, Jan K., Hollink, Iris H. I. M., Mearin, M. Luisa, Escher, Johanna C., Cerf-Bensussan, Nadine, Samsom, Janneke N.

“…Single genetic mutations predispose to very early onset inflammatory bowel disease (VEO-IBD). Here, we identify a de novo duplication of the 10p15.1…”
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IL-10 signaling in dendritic cells controls IL-1β-mediated IFNγ secretion by human CD4+ T cells: relevance to inflammatory bowel disease by Veenbergen, S., Li, P., Raatgeep, H. C., Lindenbergh-Kortleve, D. J., Simons-Oosterhuis, Y., Farrel, A., Costes, L. M. M., Joosse, M. E., van Berkel, L. A., de Ruiter, L. F., van Leeuwen, M. A., Winter, D., Holland, S. M., Freeman, A. F., Wakabayashi, Y., Zhu, J., de Ridder, L., Driessen, G. J., Escher, J. C., Leonard, W. J., Samsom, J. N.

“…Uncontrolled interferon γ (IFNγ)-mediated T-cell responses to commensal microbiota are a driver of inflammatory bowel disease (IBD). Interleukin-10 (IL-10) is…”
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Human buccal epithelium acquires microbial hyporesponsiveness at birth, a role for secretory leukocyte protease inhibitor by Menckeberg, Celia L, Hol, Jeroen, Simons-Oosterhuis, Ytje, Raatgeep, H Rolien C, de Ruiter, Lilian F, Lindenbergh-Kortleve, Dicky J, Korteland-van Male, Anita M, El Aidy, Sahar, van Lierop, Pieter P E, Kleerebezem, Michiel, Groeneweg, Michael, Kraal, Georg, Elink-Schuurman, Beatrix E, de Jongste, Johan C, Nieuwenhuis, Edward E S, Samsom, Janneke N

“…Repetitive interaction with microbial stimuli renders epithelial cells (ECs) hyporesponsive to microbial stimulation. Previously, we have reported that buccal…”
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Frequencies of circulating regulatory TIGIT+CD38+ effector T cells correlate with the course of inflammatory bowel disease by Joosse, Maria E., Menckeberg, Celia L., de Ruiter, Lilian F., Raatgeep, H. (Rolien) C., van Berkel, Lisette A., Simons-Oosterhuis, Ytje, Tindemans, Irma, Muskens, A. (Femke) M., Hendriks, Rudi W., Hoogenboezem, Remco M., Cupedo, Tom, de Ridder, Lissy, Escher, Johanna C., Veenbergen, Sharon, Samsom, Janneke N.

“…Disease heterogeneity hampers achieving long-term disease remission in inflammatory bowel disease (IBD). Monitoring ongoing tissue-localized regulatory and…”
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Colonic tolerance develops in the iliac lymph nodes and can be established independent of CD103+ dendritic cells by Veenbergen, S, van Berkel, L A, du Pré, M F, He, J, Karrich, J J, Costes, L M M, Luk, F, Simons-Oosterhuis, Y, Raatgeep, H C, Cerovic, V, Cupedo, T, Mowat, A M, Kelsall, B L, Samsom, J N

“…Tolerance to harmless exogenous antigens is the default immune response in the gastrointestinal tract. Although extensive studies have demonstrated the…”
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Anti‐inflammatory actions of phosphatidylinositol by van Dieren, Jolanda M., Simons‐Oosterhuis, Ytje, Raatgeep, H. C. (Rolien), Lindenbergh‐Kortleve, Dicky J., Lambers, Margaretha E. H., van der Woude, C. Janneke, Kuipers, Ernst J., Snoek, Gerry T., Potman, Ron, Hammad, Hamida, Lambrecht, Bart N., Samsom, Janneke N., Nieuwenhuis, Edward E. S.

“…Chronic inflammatory T‐cell‐mediated diseases such as inflammatory bowel disease (IBD) are often treated with immunosuppressants including corticosteroids. In…”
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Development and Function of Immune Cells in an Adolescent Patient With a Deficiency in the Interleukin‐10 Receptor by Veenbergen, Sharon, Leeuwen, Marieke A., Driessen, Gertjan J., Kersseboom, Rogier, Ruiter, Lilian F., Raatgeep, Rolien (H.)C., Lindenbergh‐Kortleve, Dicky J., Simons‐Oosterhuis, Ytje, Biermann, Katharina, Halley, Dicky J.J., Ridder, Lissy, Escher, Johanna C., Samsom, Janneke N.

“…ABSTRACT Objective: Monogenic defects in the interleukin‐10 (IL‐10) pathway are extremely rare and cause infantile‐onset inflammatory bowel disease (IBD)‐like…”
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Increased production of interleukin-21, but not interleukin-17A, in the small intestine characterizes pediatric celiac disease by van Leeuwen, M A, Lindenbergh-Kortleve, D J, Raatgeep, H C, de Ruiter, L F, de Krijger, R R, Groeneweg, M, Escher, J C, Samsom, J N

“…Celiac disease (CD) is caused by inflammatory CD4 + T-cell responses to dietary gluten. It is unclear whether interleukin (IL)-21 and IL-17A contribute to CD…”
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Macrophage-mediated gliadin degradation and concomitant IL-27 production drive IL-10- and IFN-γ-secreting Tr1-like-cell differentiation in a murine model for gluten tolerance by van Leeuwen, M A, Costes, L M M, van Berkel, L A, Simons-Oosterhuis, Y, du Pré, M F, Kozijn, A E, Raatgeep, H C, Lindenbergh-Kortleve, D J, van Rooijen, N, Koning, F, Samsom, J N

“…Celiac disease is caused by inflammatory T-cell responses against the insoluble dietary protein gliadin. We have shown that, in humanized mice, oral tolerance…”
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Changes in natural Foxp3(+)Treg but not mucosally-imprinted CD62L(neg)CD38(+)Foxp3(+)Treg in the circulation of celiac disease patients by van Leeuwen, Marieke A, du Pré, M Fleur, van Wanrooij, Roy L, de Ruiter, Lilian F, Raatgeep, H Rolien C, Lindenbergh-Kortleve, Dicky J, Mulder, Chris J, de Ridder, Lissy, Escher, Johanna C, Samsom, Janneke N

“…Celiac disease (CD) is an intestinal inflammation driven by gluten-reactive CD4(+) T cells. Due to lack of selective markers it has not been determined whether…”
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Inhibition of Cyclooxygenase Activity Reduces Rotavirus Infection at a Postbinding Step by ROSSEN, John W. A, BOUMA, Janneke, RAATGEEP, Rolien H. C, BÜLLER, Hans A, EINERHAND, Alexandra W. C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Hydrogen peroxide and nitric oxide in exhaled air of children with cystic fibrosis during antibiotic treatment by Jobsis, Q, Raatgeep, HC, Schellekens, SL, Kroesbergen, A, Hop, WC, de Jongste, JC

“…Cystic fibrosis (CF) patients characteristically have severe chronic airway inflammation associated with bacterial infection. A noninvasive marker of airway…”
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Hydrogen peroxide in exhaled air is increased in stable asthmatic children by Jobsis, Q, Raatgeep, HC, Hermans, PW, de Jongste, JC

“…Exhaled air condensate provides a noninvasive means of obtaining samples from the lower respiratory tract. Hydrogen peroxide (H2O2) in exhaled air has been…”
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Controlled low flow off line sampling of exhaled nitric oxide in children by Jöbsis, Q, Raatgeep, H C, Hop, W C J, de Jongste, J C

“…BACKGROUND The aim of this study was to validate exhaled nitric oxide (eNO) values obtained with an alternative off line, single breath, low flow balloon…”
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Hydrogen peroxide in exhaled air of healthy children: reference values by Jobsis, Q, Raatgeep, HC, Schellekens, SL, Hop, WC, Hermans, PW, de Jongste, JC

“…An increased content of hydrogen peroxide (H2O2), a marker of inflammation, has been described in the condensate of exhaled air from adults and children with…”
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Does Small Intestinal Atresia Affect Epithelial Protein Expression in Human Newborns? by Schaart, Maaike W, Yamanouchi, Takeshi, Nispen, Danielle JPM, Raatgeep, Rolien HC, Goudoever, Johannes B, Krijger, Ronald R, Tibboel, Dick, Einerhand, Alexandra WC, Renes, Ingrid B

“…ABSTRACT Objectives: Bowel segments distal to a congenital intestinal obstruction have been suggested to be immature. In other words, luminal components such…”
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Cyclooxygenase activity is important for efficient replication of mouse hepatitis virus at an early stage of infection by Raaben, Matthijs, Einerhand, Alexandra W C, Taminiau, Lucas J A, van Houdt, Michel, Bouma, Janneke, Raatgeep, Rolien H, Büller, Hans A, de Haan, Cornelis A M, Rossen, John W A

“…Cyclooxygenases (COXs) play a significant role in many different viral infections with respect to replication and pathogenesis. Here we investigated the role…”
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Development and Function of Immune Cells in an Adolescent Patient With a Deficiency in the Interleukin-10 Receptor by Veenbergen, Sharon, van Leeuwen, Marieke A, Driessen, Gertjan J, Kersseboom, Rogier, de Ruiter, Lilian F, Raatgeep, Rolien H C, Lindenbergh-Kortleve, Dicky J, Simons-Oosterhuis, Ytje, Biermann, Katharina, Halley, Dicky J J, de Ridder, Lissy, Escher, Johanna C, Samsom, Janneke N

“…Monogenic defects in the interleukin-10 (IL-10) pathway are extremely rare and cause infantile-onset inflammatory bowel disease (IBD)-like pathology…”
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Oxidative epithelial damage produces hyperresponsiveness of human peripheral airways by Hulsmann, A R, Raatgeep, H R, den Hollander, J C, Stijnen, T, Saxena, P R, Kerrebijn, K F, de Jongste, J C

“…The epithelium probably modulates airway smooth muscle responsiveness by producing relaxing factors, by inactivating agonists, or by acting as a physical…”
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