Search Results - "Raab, F."

Engaging homeostatic plasticity to treat depression by Workman, E R, Niere, F, Raab-Graham, K F

“…Major depressive disorder (MDD) is a complex and heterogeneous mood disorder, making it difficult to develop a generalized, pharmacological therapy that is…”
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Chemogenetic inhibition of a monosynaptic projection from the basolateral amygdala to the ventral hippocampus selectively reduces appetitive, but not consummatory, alcohol drinking‐related behaviours by Bach, Eva C., Ewin, Sarah E., Heaney, Chelcie F., Carlson, Hannah N., Ortelli, Olivia A., Almonte, Antoine G., Chappell, Ann M., Raab‐Graham, Kimberly F., Weiner, Jeffrey L.

“…Alcohol use disorder (AUD) and anxiety/stressor disorders frequently co‐occur and this dual diagnosis represents a major health and economic problem worldwide…”
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Feasibility of tuberculosis treatment monitoring by video directly observed therapy: a binational pilot study by Garfein, R. S., Collins, K., Muñoz, F., Moser, K., Cerecer-Callu, P., Raab, F., Rios, P., Flick, A., Zúñiga, M. L., Cuevas-Mota, J., Liang, K., Rangel, G., Burgos, J. L., Rodwell, T. C., Patrick, K.

“…BACKGROUND: Although directly observed therapy (DOT) is recommended worldwide for monitoring anti-tuberculosis treatment, transportation and personnel…”
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mTORC1 Is a Local, Postsynaptic Voltage Sensor Regulated by Positive and Negative Feedback Pathways by Niere, Farr, Raab-Graham, Kimberly F

“…The mammalian/mechanistic target of rapamycin complex 1 (mTORC1) serves as a regulator of mRNA translation. Recent studies suggest that mTORC1 may also serve…”
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A paradoxical switch : the implications of excitatory GABAergic signaling in neurological disorders by McArdle, Colin J, Arnone, Alana A, Heaney, Chelcie F, Raab-Graham, Kimberly F

“…Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. In the mature brain, inhibitory GABAergic signaling is…”
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Degradation of high affinity HuD targets releases Kv1.1 mRNA from miR-129 repression by mTORC1 by Sosanya, Natasha M, Huang, Peggy P C, Cacheaux, Luisa P, Chen, Chun Jung, Nguyen, Kathleen, Perrone-Bizzozero, Nora I, Raab-Graham, Kimberly F

“…Little is known about how a neuron undergoes site-specific changes in intrinsic excitability during neuronal activity. We provide evidence for a novel…”
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Potential roles of voltage-gated ion channel disruption in Tuberous Sclerosis Complex by Egido-Betancourt, Hailey X, Strowd Iii, Roy E, Raab-Graham, Kimberly F

“…Tuberous Sclerosis Complex (TSC) is a lynchpin disorder, as it results in overactive mammalian target of rapamycin (mTOR) signaling, which has been implicated…”
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Diurnal rhythms in cholinergic modulation of rapid dopamine signals and associative learning in the striatum by Stowe, Taylor A., Pitts, Elizabeth G., Leach, Amy C., Iacino, Melody C., Niere, Farr, Graul, Benjamin, Raab-Graham, Kimberly F., Yorgason, Jordan T., Ferris, Mark J.

“…Dysregulation of biological rhythms plays a role in a wide range of psychiatric disorders. We report mechanistic insights into the rhythms of rapid dopamine…”
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Rapamycin reveals an mTOR-independent repression of Kv1.1 expression during epileptogenesis by Sosanya, Natasha M, Brager, Darrin H, Wolfe, Sarah, Niere, Farr, Raab-Graham, Kimberly F

“…Abstract Changes in ion channel expression are implicated in the etiology of epilepsy. However, the molecular leading to long-term aberrant expression of ion…”
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Activity- and mTOR-Dependent Suppression of Kv1.1 Channel mRNA Translation in Dendrites by Raab-Graham, Kimberly F, Haddick, Patrick C.G, Jan, Yuh Nung, Jan, Lily Yeh

“…Mammalian target of rapamycin (mTOR) is implicated in synaptic plasticity and local translation in dendrites. We found that the mTOR inhibitor, rapamycin,…”
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Evaluation of recorded video-observed therapy for anti-tuberculosis treatment by Garfein, R. S., Liu, L., Cuevas-Mota, J., Collins, K., Catanzaro, D. G., Muñoz, F., Moser, K., Chuck, C., Higashi, J., Bulterys, M. A., Raab, F., Rios, P.

“…BACKGROUND: Asynchronous video directly observed therapy (VDOT) may reduce tuberculosis (TB) program costs and the burden on patients. We compared VDOT…”
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Chronic Ethanol Exposures Leads to a Negative Affective State in Female Rats That Is Accompanied by a Paradoxical Decrease in Ventral Hippocampus Excitability by Bach, Eva C, Morgan, James W, Ewin, Sarah E, Barth, Samuel H, Raab-Graham, Kimberly F, Weiner, Jeffrey L

“…Alcohol use disorder (AUD) differentially impacts men and women and a growing body of evidence points to sex-dependent adaptations in a number of brain…”
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Beating the Spin-Down Limit on Gravitational Wave Emission from the Crab Pulsar by Abbott, R, Arain, M. A, Araya, M, Aston, S, Bantilan, H, Barr, B, Boschi, V, Burmeister, O, Byer, R. L, Cagnoli, G, Camp, J. B, Castaldi, G, Charlton, P, Chatterji, S, Clark, D, Cook, D, Corbitt, T, Cutler, R. M, Díaz, M, Dooley, K. L, Doomes, E. E, Duke, I, Dupuis, R. J, Fricke, T, Giaime, J. A, Goggin, L, Grant, A, Gray, M, Grimaldi, F, Hallam, J. M, Hanna, C, Harms, J, Hayler, T, Hewitson, M, Hild, S, Hosken, D, Ito, M, Johnson, W. W, Kawabe, K, Kawazoe, F, Kells, W, Kopparapu, R. K, Kozak, D, Lam, P. K, Leindecker, N, Lindquist, P, Lubinski, M, Lück, H, MacInnis, M, Mailand, K, Markowitz, J, Martin, I, Matichard, F, Mavalvala, N, McHugh, M, McIntyre, G, McKenzie, K, Mendell, G, Mercer, R. A, Messenger, C. J, Munch, J, Pedraza, M, Plissi, M. V, Postiglione, F, Quetschke, V, Rainer, N, Rakhmanov, M, Ramsunder, M, Rehbein, H, Robertson, N. A, Roddy, S, Romie, J, Ruet, L, Samidi, M, de la Jordana, L. Sancho, Sathyaprakash, B. S, Schofield, R, Sears, B, Siemens, X, Sigg, D, Smith, J. R, Smith, M. R, Smith, N. D, Sorazu, B, Stochino, A, Strom, D. M, Sung, M, Takahashi, H, Thorne, K. A, Thüring, A, Tokmakov, K. V, van der Sluys, M, Wallace, L, Weinert, M, Wen, S, Williams, L, Willke, B, Wilmut, I, Woan, G, Yamamoto, H

“…We present direct upper limits on gravitational wave emission from the Crab pulsar using data from the first 9 months of the fifth science run of the Laser…”
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Chronic Social Isolation Stress during Peri-Adolescence Alters Presynaptic Dopamine Terminal Dynamics via Augmentation in Accumbal Dopamine Availability by Karkhanis, Anushree N, Leach, Amy C, Yorgason, Jordan T, Uneri, Ayse, Barth, Samuel, Niere, Farr, Alexander, Nancy J, Weiner, Jeffrey L, McCool, Brian A, Raab-Graham, Kimberly F, Ferris, Mark J, Jones, Sara R

“…Chronic peri-adolescent stress in humans increases risk to develop a substance use disorder during adulthood. Rats reared in social isolation during…”
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FMRP regulates an ethanol-dependent shift in GABABR function and expression with rapid antidepressant properties by Wolfe, Sarah A., Workman, Emily R., Heaney, Chelcie F., Niere, Farr, Namjoshi, Sanjeev, Cacheaux, Luisa P., Farris, Sean P., Drew, Michael R., Zemelman, Boris V., Harris, R. Adron, Raab-Graham, Kimberly F.

“…Alcohol promotes lasting neuroadaptive changes that may provide relief from depressive symptoms, often referred to as the self-medication hypothesis. However,…”
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Implications for the Origin of GRB 070201 from LIGO Observations by Abbott, R, Agresti, J, Araya, M, Ashley, M, Bantilan, H, Barr, B, Blackburn, K, Boschi, V, Bose, S, Brau, J. E, Bunkowski, A, Byer, R. L, Cagnoli, G, Camp, J. B, Cantley, C. A, Castaldi, G, Charlton, P, Chatterji, S, Chiadini, F, Christensen, N, Coldwell, R, Cook, D, Croce, R. P, Cumming, A, Davies, G, Degallaix, J, Demma, T, Desai, S, Dietz, A, Drever, R. W. P, Fazi, D, Franzen, A, Gholami, I, Giampanis, S, Goda, K, Goetz, E, Gras, S, Gray, C, Grosso, R, Hanna, C, Harms, J, Harry, G, Hayler, T, Hewitson, M, Hild, S, Hosken, D, Ito, M, Ivanov, A, Jones, D. I, Kawabe, K, Kells, W, Kissel, J. S, Kokeyama, K, Kopparapu, R. K, Kozak, D, Krishnan, B, Lantz, B, Lazzarini, A, McGuire, S. C, McKenzie, K, Mendell, G, Messenger, C. J, Mitrofanov, V. P, Munch, J, Ottaway, D. J, Pinto, I. M, Rabeling, D, Ribichini, L, Sakata, S, Samidi, M, Saraf, S, Sato, S, Schediwy, S, Sears, B, Shawhan, P, Sigg, D, Somiya, K, Strain, K. A, Summerscales, T. Z, Sun, K.-X, Sutton, P. J, Taylor, R, Thorne, K. S, Vecchio, A, Vorvick, C, Vyachanin, S. P, Waldman, S. J, Wallace, L, Weiss, R, Whelan, J. T, Whiting, B. F, Willems, P. A, Wipf, C. C, Woods, D, Wu, W, Yoshida, S, Zanolin, M, Zhao, C, Zucker, M, Zweizig, J

“…We analyzed the available LIGO data coincident with GRB 070201, a short- duration, hard-spectrum -ray burst (GRB) whose electromagnetically determined sky…”
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Design and implementation of a randomized controlled social and mobile weight loss trial for young adults (project SMART) by Patrick, K, Marshall, S.J, Davila, E.P, Kolodziejczyk, J.K, Fowler, J.H, Calfas, K.J, Huang, J.S, Rock, C.L, Griswold, W.G, Gupta, A, Merchant, G, Norman, G.J, Raab, F, Donohue, M.C, Fogg, B.J, Robinson, T.N

“…Abstract Purpose To describe the theoretical rationale, intervention design, and clinical trial of a two-year weight control intervention for young adults…”
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Search for gravitational-wave bursts from soft gamma repeaters by Abbott, B, Abbott, R, Adhikari, R, Ajith, P, Allen, B, Allen, G, Amin, R, Anderson, S B, Anderson, W G, Arain, M A, Araya, M, Armandula, H, Armor, P, Aso, Y, Aston, S, Aufmuth, P, Aulbert, C, Babak, S, Ballmer, S, Bantilan, H, Barish, B C, Barker, C, Barker, D, Barr, B, Barriga, P, Barton, M A, Bartos, I, Bastarrika, M, Bayer, K, Betzwieser, J, Beyersdorf, P T, Bilenko, I A, Billingsley, G, Biswas, R, Black, E, Blackburn, K, Blackburn, L, Blair, D, Bland, B, Bodiya, T P, Bogue, L, Bork, R, Boschi, V, Bose, S, Brady, P R, Braginsky, V B, Brau, J E, Brinkmann, M, Brooks, A, Brown, D A, Brunet, G, Bullington, A, Buonanno, A, Burmeister, O, Byer, R L, Cadonati, L, Cagnoli, G, Camp, J B, Cannizzo, J, Cannon, K, Cao, J, Cardenas, L, Casebolt, T, Castaldi, G, Cepeda, C, Chalkley, E, Charlton, P, Chatterji, S, Chelkowski, S, Chen, Y, Christensen, N, Clark, D, Clark, J, Cokelaer, T, Conte, R, Cook, D, Corbitt, T, Coyne, D, Creighton, J D E, Cumming, A, Cunningham, L, Cutler, R M, Dalrymple, J, Danzmann, K, Davies, G, Debra, D, Degallaix, J, Degree, M, Dergachev, V, Desai, S, Desalvo, R, Dhurandhar, S, Díaz, M, Dickson, J, Dietz, A, Donovan, F, Dooley, K L, Doomes, E E, Drever, R W P, Duke, I

“…We present a LIGO search for short-duration gravitational waves (GWs) associated with soft gamma ray repeater (SGR) bursts. This is the first search sensitive…”
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Limits on gravitational-wave emission from selected pulsars using LIGO data by Abbott, B, Abbott, R, Adhikari, R, Ageev, A, Allen, B, Amin, R, Anderson, S B, Anderson, W G, Araya, M, Armandula, H, Ashley, M, Asiri, F, Aufmuth, P, Aulbert, C, Babak, S, Balasubramanian, R, Ballmer, S, Barish, B C, Barker, C, Barker, D, Barnes, M, Barr, B, Barton, M A, Bayer, K, Beausoleil, R, Belczynski, K, Bennett, R, Berukoff, S J, Betzwieser, J, Bhawal, B, Bilenko, I A, Billingsley, G, Black, E, Blackburn, K, Blackburn, L, Bland, B, Bochner, B, Bogue, L, Bork, R, Bose, S, Brady, P R, Braginsky, V B, Brau, J E, Brown, D A, Bullington, A, Bunkowski, A, Buonanno, A, Burgess, R, Busby, D, Butler, W E, Byer, R L, Cadonati, L, Cagnoli, G, Camp, J B, Cantley, C A, Cardenas, L, Carter, K, Casey, M M, Castiglione, J, Chandler, A, Chapsky, J, Charlton, P, Chatterji, S, Chelkowski, S, Chen, Y, Chickarmane, V, Chin, D, Christensen, N, Churches, D, Cokelaer, T, Colacino, C, Coldwell, R, Coles, M, Cook, D, Corbitt, T, Coyne, D, Creighton, J D E, Creighton, T D, Crooks, D R M, Csatorday, P, Cusack, B J, Cutler, C, D'Ambrosio, E, Danzmann, K, Daw, E, DeBra, D, Delker, T, Dergachev, V, DeSalvo, R, Dhurandhar, S, Di Credico, A, Díaz, M, Ding, H, Drever, R W P, Dupuis, R J, Edlund, J A, Ehrens, P, Elliffe, E J, Etzel, T, Evans, M

“…We place direct upper limits on the amplitude of gravitational waves from 28 isolated radio pulsars by a coherent multidetector analysis of the data collected…”
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mTOR referees memory and disease through mRNA repression and competition by Raab‐Graham, Kimberly F., Niere, Farr

“…Mammalian target of rapamycin (mTOR) activity is required for memory and is dysregulated in disease. Activation of mTOR promotes protein synthesis; however,…”
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